All National Institute of Allergy and Infectious Diseases articles
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NewsScientists find weak points on Epstein-Barr virus
Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines.
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NewsSwitching to vegan or ketogenic diet rapidly impacts immune system - and gut microbiome
A study found that switching to a vegan diet prompted responses linked to innate immunity, while the keto diet elicited responses associated with adaptive immunity, along with metabolic changes and shifts in the gut microbiomes.
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NewsResearchers create safer form of Coxiella burnetii for scientific use
Scientists have unexpectedly discovered that the weakened form of the bacteria Coxiella burnetii (C. burnetii) not typically known to cause disease, has naturally acquired an ability to do so.
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NewsHIV antibodies protect animals in proof-of-concept study
Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people.
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NewsResearchers ID opportunities to improve future HIV vaccine candidates
An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study.
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NewsResearchers receive $423,500 for study to improve outcomes from fungal infections
Researchers have received a $423,500 for research aimed at reducing disease and mortality rates associated with Aspergillus infections by focusing on the molecular pathways in the fungus that mediate inflammatory host responses.
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NewsStudy reveals how young children’s immune systems tame SARS-CoV-2
A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.
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NewsHypervirulent bacteria emerging in healthy people
New ’hypervirulent’ strains of the bacterium Klebsiella pneumoniae have emerged in healthy people in community settings, prompting researchers to investigate how the human immune system defends against infection.
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NewsDrinking water quality linked to lung infections in people with cystic fibrosis
High levels of some minerals and metals in environmental water supplies may increase the risk of nontuberculous mycobacteria (NTM) pulmonary infections in people with cystic fibrosis, according to a new study.
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NewsInvestigational three-month TB regimen is safe but ineffective
The first clinical trial of a three-month tuberculosis (TB) treatment regimen is closing enrollment because of a high rate of unfavorable outcomes with the investigational course of treatment.
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NewsStudy reveals how drug resistant bacteria secrete toxins
Research suggests that reducing virulence in drug resistant infections rather than trying to kill bacteria outright may offer an answer to antimicrobial resistance.
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NewsNew inoculation based on Ebola VSV vaccine concept protects macaques
Researchers have successfully developed a vaccine against Sudan virus (SUDV) based on the licensed Ebola virus (EBOV) vaccine.
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NewsMarburg vaccine shows promising results in first-in-human study
An experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial, according to a new paper.
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NewsProbiotic markedly reduces staph colonisation in phase 2 trial
A approach to control Staphylococcus aureus bacterial colonization in people—using a probiotic instead of antibiotics—was found to be safe and highly effective in a Phase 2 clinical trial.
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NewsExperimental monoclonal antibodies take the fight to Epstein-Barr virus
Researchers have discovered a panel of investigational monoclonal antibodies (mAbs) targeting different sites of the Epstein-Barr virus (EBV) blocked infection when tested in human cells in a laboratory setting.
