All Mpro articles
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News
Scientists assess efficacy of clinical drugs targeting SARS-CoV-2 main protease
A critical player in the virus’s life cycle is the main protease (Mpro), also known as NSP5 or 3CL protease, which plays a crucial role in the cleavage and maturation of SARS-CoV-2 proteins within the host cells.
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News
Crowd-sourced potent SARS-CoV-2 antiviral lead compound announced by COVID Moonshot Consortium
More than 200 scientists and students, triggered by a Twitter appeal, have identified and developed novel compounds with excellent antiviral activity against a key enzyme of the SARS-COV-2 virus, the main protease (Mpro).