More News – Page 88
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NewsComplement system response to AAV vector gene therapy
Recent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene transfer – activation of the complement system.
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NewsGut microbes may cause some COVID-19 patients to have higher blood clot risk
A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis – the formation of blood clots – and is accumulated in individuals with COVID-19.
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NewsHigh resolution techniques reveal clues to early microbes in 3.5 billion-year-old biomass
A research team has found new clues about the formation and composition of the 3.5bn year old rocks of Pilbara Craton, which contain traces of the microorganisms that lived at that time.
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NewsStudy examines medical mystery of child hepatitis outbreak
A study into an unexpected wave of severe hepatitis cases in 2022 supports the theory that it was caused by an infection of different viruses at the same time, but also reveals cases were higher and more severe than initially thought.
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NewsNew method detects pathogens faster and more accurately by melting DNA
A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, producing results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
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NewsPhage therapy eradicates pan-resistant priority pathogen in vivo, study shows
A new study describes the use of phage therapy to eradicate multi-drug resistant Pseudomonas aeruginosa infections in a living organism (in vivo) with important new implications to antibiotic resistance.
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NewsStudy of usefulness of lockdowns during epidemics identifies alternate solution
Researchers found that small nonpharmaceutical interventions can tip the optimal response between very different approaches to slowing viral spread and identified an alternate approach that has previously not been recognized as effective.
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NewsResearchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
A new class of antibiotics not only shows promise against a broad array of bacterial infections but can also evade the dreaded resistance that has been rendering our current generation of first-line antibiotics ineffective.
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NewsLong-acting HIV treatment demonstrates efficacy in people with challenges taking daily medicine as prescribed
Long-acting antiretroviral therapy (ART) with cabotegravir and rilpivirine was superior in suppressing HIV replication compared to daily oral ART in people who had been unable to maintain viral suppression through an oral daily regimen, according to interim data from a randomized trial. Source: NIAID Colorized transmission electron micrograph ...
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NewsScientists win $434k grant to induce microbes to desert their protective biofilm
Researchers are pursuing biofilm dispersal agents such as specific enzymes in hopes the enzymes can induce microbes to leave the safety of the protective biofilm and become more susceptible to antibiotics.
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NewsScientists craft enhanced viral structure in VLP vaccines through polymer restructuring
Researchers reported a viromimetic polymer nanoparticle vaccine (VPNVax), crafted by rearranging the RBD proteins of the coronavirus and modifying them onto the surface of pre-assembled polyethylene glycol-polylactic acid polymer nanoparticles.
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NewsUptake of HIV prevention medication doubles with mix of digital health interventions
A combination of interventions of one-on-one telehealth coaching, peer support forums, and automated text messages more than doubled the use of the HIV prevention strategy, called PrEP, among younger, at-risk Americans.
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NewsStudy finds high number of persistent COVID-19 infections in the general population
A new study has found that a high proportion of SARS-CoV-2 infections in the general population lead to persistent infections lasting a month or more, with some of these showing a high number of mutations.
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NewsBat mating swarms may be the key to solving the next pandemic
The evolution of viral tolerance in Myotis bats may help scientists prevent future pandemics, say researchers.
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NewsFatty acid produced by gut bacteria directly influences fat metabolism in animals
Researchers investigating gut bacteria that produce fatty acids with a special chemical structure, known as a cyclopropane ring, showed that these can be converted into signals that turn on fat desaturation in the nematode C. elegans.
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NewsDroughts may trigger HIV transmission increase among women in rural sub-Saharan Africa
Droughts have the potential to increase the spread of HIV for women living in rural parts of Africa, researchers at the University of Bristol have found.
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NewsFungi that live in healthy plants are sensitive to climate change
Findings more than a decade in the making reveal a rich diversity of beneficial fungi living in boreal forest trees, with implications for the health of forests.
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NewsMicrobiome studies explore why more women develop Alzheimer’s disease
Two new studies from the University of Chicago investigate the roles of the gut microbiome and estrogen in the differing rates of Alzheimer’s disease among women and men.
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NewsNanoparticles containing lupeol treat visceral leishmaniasis with scant side effects
In animal tests conducted at São Paulo State University (UNESP), the strategy reduced spleen and liver parasite numbers by 99.9%.
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NewsSurge in gonorrhoea cases in Denmark: up by 46% between 2021 and 2022
An observed rise in gonorrhoea cases particularly affected younger women and men who have sex with women, indicating a potential shift in infection and transmissibility dynamics across the country.
