More News – Page 68
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Treatment for deadly superbug C. diff may be weakening
The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research.
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Scientists deploy synthetic amyloids to figure out ways of targeting biofilms
New research being presented at the Letters in Applied Microbiology ECS Research Symposium this May will reveal how scientists are investigating how macrophages can be used to break down amyloid plaques in biofilms.
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Cocktails of antibiotics, probiotics and prebiotics hold promise in treating a common form of irritable bowel syndrome
Personalised “cocktails” of antibiotics, probiotics and prebiotics hold great promise in the treatment of a common form of irritable bowel syndrome (IBS), a new study suggests.
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Experts developing way to harness Nobel Prize winning CRISPR technology to deal with antimicrobial resistance (AMR)
Scientists show how the latest CRISPR-Cas gene editing technology can be used to help modify and attack AMR bacteria.
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Making transfusion-transmitted malaria in Europe a thing of the past
The current strategy used in Europe to mitigate malaria transfusion risk is efficient with just 10 reported cases over the past 20 years, but current serological tests used to identify “at risk” donors are not sensitive enough to completely eliminate the risk.
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CRISPR is promising to tackle antimicrobial resistance - but remember bacteria can fight back
Experts are looking to use the Nobel winning technology to target resistance genes and make bacteria sensitive to first line antibiotics again; but the bacteria have ways to fight back.
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Experimental NIH malaria monoclonal antibody protective in Malian children
One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country’s six-month malaria season, according to the results of a mid-stage clinical trial.
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Antimicrobial-resistant hospital infections remain at least 12% above pre-pandemic levels, major US study finds
Despite progress in combating antimicrobial resistance (AMR) in the USA since its peak during the COVID-19 pandemic, hospital-acquired AMR infections remain well above pre-pandemic levels, according to a major new study examining AMR before, during, and after the COVID-19 pandemic in 120 US hospitals. Source: NIAID Colorized scanning ...
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Antibiotic use in patients hospitalised with COVID-19 appears to have no beneficial effect on clinical outcomes
An analysis of more than 1,300 German adults hospitalised with moderate COVID-19 finds treatment with antibiotics was associated with five times greater likelihood of COVID-19 deterioration compared to patients not given antibiotics.
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Effective health comms needed to save lives during epidemics
An African infectious disease expert discusses how effective public health communication is critical for fighting epidemics and saving lives across the African continent.
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Barley plants fine-tune their root microbial communities through sugary secretions
Different types of barley recruit distinct communities of soil microbes to grow around their roots by releasing a custom mix of sugars and other compounds, according to a new study.
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Vitamin D availability enhances antitumor microbes in mice
Dietary vitamin D modulates the gut microbiome to enhance the response to cancer immunotherapies, according to a new study in mice.
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Wastewater plant yields giant viruses that infect deadly parasite
Researchers have discovered giant viruses that infect the single-celled organism Naegleria fowleri which ranks among the deadliest human parasites.
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Climate change linked surge in malaria transmission could be less than feared
Despite concerns about the potential impact of climate change on increasing malaria risk, there is still limited understanding of how temperature affects malaria transmission – until now.
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Microbiota enterotoxigenic Bacteroides fragilis-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance
A new study highlights the importance of considering the microbiome as a factor in cancer treatment and offers a promising avenue for developing novel therapeutic strategies aimed at enhancing efficacy of breast cancer treatments.
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Experts call for global genetic warning system to combat the next pandemic and antimicrobial resistance
Clinical and public health microbiologists have called for investment in technology, capacity, expertise, and collaboration to put genomic surveillance of pathogens at the forefront of future pandemic preparedness.
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Synthetic droplets cause a stir in the primordial soup
A synthetic droplet may give researchers clues on how the simplest forms of life on the planet could navigate their surroundings.
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Paclitaxel-induced immune dysfunction and activation of transcription factor AP-1 facilitate Hepatitis B virus replication
A study finds that Paclitaxel treatment directly promotes HBV replication and transcription, leading to HBV reactivation in HBV stable expression cell models, HBV natural infection cell models, and HBV transgenic mouse models.
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Study finds artificial intelligence can develop treatments to prevent superbugs
Researchers developed an AI model that can determine the best combination and timeline to use when prescribing drugs to treat a bacterial infection, based solely on how quickly the bacteria grow given certain perturbations.
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To mask or not to mask? Understanding public health behaviors during COVID-19
Researchers from Osaka University find that mask-wearing behavior depends on complex relationships between context and social norms.