More News – Page 63
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Astragalus polysaccharide enhances voriconazole metabolism under inflammatory conditions through the gut microbiota
Astragalus polysaccharide alleviates the reduction of VRC metabolism induced by LPS by inhibiting lipid accumulation and inflammatory cytokine levels in the serum and liver and improving the metabolic function of the liver, a new study shows.
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Decoding the complex genetic network of antimicrobial resistance in Campylobacter jejuni
A study focused on tetracycline resistance genes tetO and tetM - using phylogenetic tree analysis, it provided valuable insights into the genetic landscape and variants associated with C. jejuni.
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Marine bacteria team up to produce a vital vitamin
Researchers have conducted various experiments to analyse the interaction between two species of marine bacteria from the North Sea in the synthesis of vitamin B12.
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An adjuvant made in yeast could lower vaccine cost and boost availability
Scientists have wielded the power of synthetic biology to produce the active ingredient of soap bark, a molecule called QS-21, in yeast - a more environmentally friendly way to produce a key ingredient of vaccines.
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Swarms of miniature robots clean up microplastics and microbes simultaneously
A study describes swarms of microscale robots (microrobots) that captured bits of plastic and bacteria from water. Afterward, the bots were decontaminated and reused.
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AMI welcomes new 5-year UK plan to combat antimicrobial resistance
Applied Microbiology International has welcomed the UK government’s new national action plan on antimicrobial resistance to protect people and animals from the risk of drug-resistant infections.
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Loss of large herbivores affects interactions between plants and their natural enemies, study shows
Researchers in Brazil compared leaf damage caused by insects and pathogens in areas with and without the presence of mammals such as tapirs, deer and peccaries.
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Mobile teams bring COVID-19 vaccines to rural villages in Sierra Leone
A new international research project showed that intervention with mobile vaccination teams in Sierra Leone is an effective way of reaching rural populations to increase vaccination uptake.
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US geographic region results in vastly different anal cancer risk for people with HIV
A new study that followed a cohort of more than 110,000 people establishes significant disparities in the risk of anal cancer for people with HIV, depending on the region of the country they live in.
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Scientists warn of overuse of antibiotics in newborns with suspected sepsis
Newborns in Sweden are given antibiotics for suspected sepsis to an unjustified extent, reveals a study of more than one million newborns. Despite a significant reduction in sepsis rate in the group, the use of antibiotics has not decreased.
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From treatment to tap: discovering the secrets of pathogen survival in drinking water systems
Scientists at the University of Pittsburgh are investigating how some DWPIs can survive drinking water treatment processes and determine better treatment processes to stop them from entering the human body.
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Gut bacteria metabolite shows promise for fighting inflammatory bowel disease
A new study highlights the molecular mechanisms underlying the anti-inflammatory effects of KetoC, a gut bacteria-generated linoleic acid metabolite, using mouse models.
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Tenofovir alafenamide treatment achieves positive results in Chinese chronic hepatitis B patients
A five-year treatment regime with tenofovir alafenamide achieves high rates of viral suppression, alanine aminotransferase normalization, and favorable bone and renal safety in Chinese chronic hepatitis B patients.
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Key role found for gut epithelial cells in the defense against deadly diarrheal infections
A newly identified subset of intestinal epithelial cells act as both the major target and a key responder in a mouse model of gut infection by the bacteria Citrobacter rodentium.
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Science academies discuss global health approaches for future pandemics
Experts will discuss questions concerning global healthcare policy and pandemic prevention at the Leopoldina International Virtual Panel on Tuesday 14 May.
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Engineers develop innovative microbiome analysis software tools
Since the first microbial genome was sequenced in 1995, scientists have reconstructed the genomic makeup of hundreds of thousands of microorganisms and have even devised methods to take a census of bacterial communities on the skin, in the gut, or in soil, water and elsewhere based on bulk samples, leading ...
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Transfected SARS-CoV-2 spike DNA suppresses cancer cell response to chemotherapy
Researchers have examined the interaction between SARS-CoV-2 spike, p53 and MDM2 (E3 ligase, which mediates p53 degradation) in cancer cells using an immunoprecipitation assay.
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Progression of herpesvirus infection remodels mitochondrial organization and metabolism
Researchers have found that herpesvirus infection modifies the structure and normal function of the mitochondria in the host cell. The new information will help to understand the interaction between herpesvirus and host cells.
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Researchers discover link between breast changes and UTIs
Scientists have found that UTIs in mice can provoke a bodily response that results in structural changes in breast tissue. Remarkably, these changes are reversible once the infections are resolved.
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Genomes of ‘star algae’ shed light on origin of land plants
An international group of researchers has generated the first genome data of on four filamentous ‘star algae’ of the genus Zygnema - among the most closely related to land plants.