All Microbiological Methods articles – Page 5
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Persistent proteins may influence metabolomics results
Scientists have identified more than 1,000 previously undetected proteins in common metabolite samples, which persist despite extraction methods designed to weed them out.
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Researchers develop a way to make lifesaving phages accessible, transportable and much easier to use
Researchers have developed a simple new way to store, identify, and share phages, making them more accessible to patients who need them.
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Scientists pioneer comprehensive derivative synthesis method for developing new antimicrobial drugs
A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant bacteria.
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Synthetic biology reveals the secrets of life without oxygen
Long before photosynthesis brought free oxygen into the world, the earth was already populated by numerous organisms. Oxygen was life-threatening for them and therefore they developed completely different metabolic pathways to those we know from plants, animals and humans. Source: Gulimila Shabuer / Leibniz-HKI and EMZ Jena Scanning ...
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Discharge of untreated hospital effluent is a key driver of multidrug resistance, study finds
A new study has highlighted the discharge of untreated hospital effluent to the environment as a major driver of multidrug resistance among the microbial community.
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Imaging techniques reveal detail of soybean nodule structures for improved nitrogen fixation efficiency
Researchers have used synchrotron-based X-ray microcomputed tomography to non-invasively obtain high-quality 3D images of fresh soybean root nodules, quantifying the volumes of the central infected zone and vascular bundles.
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Experts identify hazards of AI research for engineering biology
Hazards posed by using data-centric methods to engineer biology have been identified by experts with the aim of making future research safer.
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Scientists unveil cholangiocyte organoid system for Cryptosporidium parvum cultivation
Researchers have established a culture system for the cultivation of Cryptosporidium parvum derived from mouse and bovine cholangiocyte organoids (Chol-orgs). Source: EPA/H.D.A. Lindquist Immunofluorescence image of Cryptosporidium parvum oocysts, purified from murine fecal material. The study, published in hLife, is led by Prof. Feng (College of Veterinary ...
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WHO updates laboratory biosecurity guidance
WHO recently issued updated guidance for national authorities and biomedical laboratories to manage biological risks, including strengthening of cybersecurity measures and reducing risks from new technologies.
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New findings may fix the replicability crisis in microbiome research
Scientists report that daily fluctuations in the gut alter the microbiome so significantly that different bugs populate it in the morning and in the evening.
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Novel 3D hydrogel culture to study TB infection and treatment
Researchers have designed a novel 3D hydrogel culture system that mimics the mammalian lung environment, providing a platform to track and study how tuberculosis bacteria infect lung cells and test the efficacy of therapeutics used to treat TB.
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Researchers develop novel AI algorithm for analyzing microfossils
Microfossil analysis allows us to map the subsurface and understand past geological times. In research labs all over the world geologists spend countless hours looking through the microscope identifying and counting microfossils extracted from sedimentary rock below the seabed. Source: ZooFari Photo of an unidentified 10 million year ...
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Breakthrough in nanoscale force measurement opens doors to unprecedented biological insights
Groundbreaking research has revealed a new way to measure incredibly minute forces at the nanoscale in watery solutions, pushing the boundaries of what scientists know about the microscopic world.
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SKAN Research Trust and Quadram Institute Bioscience to develop novel microbial therapies
SKAN Research Trust and Quadram Institute Bioscience will apply the TraDIS-Xpress platform to study the action of traditional medical compounds on bacteria, aiding in the reformulation and development of novel antibacterial regimens.
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Scientists adapt astronomy method to unblur microscopy images
To make adaptive optics more widely available to biologists, researchers have turned their attention to a class of techniques called phase diversity that’s been widely used in astronomy but is new to the life sciences.
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New HIV reporter model: Visualizing HIV viral dynamics in cells with dual fluorescence
Researchers have developed a novel viral reporter system that allows for real-time visualization of HIV dynamics post-viral infection. HIV-Tocky features dual fluorescence to illuminate the process of provirus silencing and reactivation.
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New 3D printed imaging device combines education and microbial research
Researchers have developed a 3D-printed imaging device for schools and research centres to study microbes. It enables schools to observe natural phenomena, while researchers will gain useful knowledge about the light-activated bacteria.
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Careers
Scientists put Mars DNA sampling protocols to the test with help from AMI grant
Thanks to support from Applied MIcrobiology International, scientists testing sampling collection protocols in Mars analogue conditions have shown that non-scientists will be able to replicate the tests as long as they follow the methods.
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Forget the freezer - air-dried soils will still give up their microbial secrets
Scientists have found that soil stored under refrigerated or air-dried conditions can still retain the needed information for understanding microbial community composition and structure for many years.
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Novel diagnostic tech captures disease markers in a snap
Researchers have introduced Flocculation via Orbital Acoustic Trapping (FLOAT), a novel method that markedly enhances the extraction of extracellular vesicles from biological fluids.