All Microbiological Methods articles
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Rice research team creates universal RNA barcoding system for tracking gene transfer in bacteria
An interdisciplinary group of researchers at Rice University has developed an innovative RNA “barcoding” method to track gene transfer in microbial communities, providing new insights into how genes move across species.
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New method uncovers dynamic microbial community in coastal sediments
Scientists utilises single celll genomics and cell staining approaches to investigate the respiratory rates and metabolic activities of the diverse microbial communities in low biomass aqautic environments, such as Maine’s coastal sediments.
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Microbiome: Researchers improve bacterial analysis for clinical applications
Different extraction methods can obtain the DNA of certain bacterial species differently, which can significantly distort the determined microbiome composition. Scientists have developed a computer-based method for correcting extraction bias.
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TB vaccine candidate provides ‘elite’ protection
A tuberculosis vaccine candidate under development shows complete protection and superior immune response in nonhuman primates compared to the existing BCG vaccine.
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Damaged but not defeated: Bacteria use nano-spearguns to retaliate against attacks
Scientists used state-of-the-art microscopy technology to mimic a nano-speargun, the type VII secretion system, used as a bacterial pinpoint counterattack tactic in response to cell envelope damage against rival bacteria.
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Scientists reveal anti-bacterial role of plant metabolite
A study shows that a plant metabolite, erucamide, is able to target and disrupt a protein assembly of Gram-negative bacterial pathogens, thus inhibiting their virulence. Understanding the metabolite’s molecular mechanisms could protect crops from infection.
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Scientists track pneumonia-causing bacteria as they infect the blood stream
A new study has shown various dissemination patterns can be adopted by Klebsiella pneumoniae that causes systemic infection, i.e. bacteremia.
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A rapid and reproducible method for generating germ-free Drosophila melanogaster
Scientists have introduced a refined method for the production of germ-free Drosophila, complemented by a straightforward verification process to ascertain its efficacy.
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Lung abnormalities seen in children and teens with long COVID
An advanced type of MRI uncovers significant lung abnormalities in children and adolescents with long COVID, according to a new study. PREFUL MRI doesn’t require the use of radiation or intravenous contrast agents and can be done while the patient breathes freely.
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Laser-powered device tested on Earth could help us detect microbial fossils on Mars
Scientists hoping to identify fossil evidence of ancient Martian microbial life have now found a way to test their hypothesis, proving they can detect the fossils of microbes in gypsum samples that are a close analogy to sulfate rocks on Mars.
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Nitrogen fixation on marine snow particles is widespread in the world's oceans
Researchers have shown that bacteria attached to marine snow particles can fix N2 over a wide range of temperatures in the global oceans, from the tropics to the poles, and from the surface to the abyss, accounting for about 10% of the overall N2 fixation in oceans.
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Scottish bio-tech company secures £3.4m investment
Scottish biotech engineering company uFraction8 has secured £3.4m in new investment following the completion of a funding round led by Foresight Group.
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Use of AI-driven science could yield unexpected consequences for the healthcare sector, paper warns
Unexpected consequences may arise if scientific conclusions formed using AI-driven data are applied to the healthcare sectors, a new opinion piece warns.
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Researchers create world’s largest digital microbe collection to transform health research
Researchers have created the world’s largest collection of digital microbes - nearly a quarter of a million computer models - to help revolutionise our understanding of the human microbiome and its impact on health.
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A new system to study phytoplankton: Crucial species for planet Earth
Researchers have come up with a new way to study phytoplankton. They’ve built a system that can measure the light given off by individual phytoplankton cells, which tells them how efficiently each individual is using light.
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New method ‘fishes’ for bacterial STI DNA, revealing how Chlamydia spreads and adapts
Scientists have developed a cutting-edge “target enrichment” technology for bacterial STIs. Using specially designed molecular probes, they “fished” for bacterial STI DNA from clinical samples, enabling high-resolution genome analysis.
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New modeling approach could help design antivirals for shape-shifting viruses
New research utilizes an innovative computational modeling approach to capture the complex and diverse shapes that viral proteins can adopt.
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A realistic ‘micro-gut’ model reflects the relationship between gut microbes and human diseases
An innovative and more physiologically relevant 3D micro-gut model, known as Gut-Microbiome on a chip (GMoC), provides an in-depth understanding of the complex interactions between the microbial community within the gut microbiome and their impacts on human gut health.
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Bacteria, brains, and sugar: scientists uncover new connections
Using a new method to study how carbohydrates modify proteins, scientists have discovered that gut bacteria can alter molecular signatures in the brain.
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Students tackle drug resistance by teaching machine learning
Researchers using machine learning to predict drug resistance in patients have published a step-by-step machine learning tutorial for beginners.