All Microbiological Methods articles
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mRNA vaccines for disease outbreaks can be synthesized in less time with new technique
Researchers have developed an innovative synthesis technology capable of producing high purity, fully chemically synthesized mRNA, cutting out the slower enzyme reactions, which could lead to mitigation of future infections at a preliminary stage.
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Super-strong bacterial cellulose macrofibers made simple with TAT technique
Researchers have engineered a novel method to create high-performance macrofibers with enhanced mechanical properties and humidity response.
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Mouse model clarifies link between prostate cancer and gut bacteria
Researchers have investigated whether a mouse model of the disease can be used to explore the underlying mechanisms behind the relationship of changes in the composition of gut bacteria and the risk and progression of prostate cancer.
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Single-cell genomics decodes bacteria genomes and uncovers new species
A team of researchers has developed a groundbreaking single-cell genome approach. This approach, which reads information from individual cells, offers a promising alternative to conventional metagenomics.
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Scientists can pinpoint bacterial needle in haystack using fluorescence
Bacterial troublemakers are able to survive antibiotics and are not detected by diagnostic antibiotic resistance testing. A new method has been developed to look at single bacteria and to find the antibacterial resistant ones, or the troublemakers, among them.
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New mouse models offer valuable window into COVID-19 infection
Scientists have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19 because their cells were engineered to include two important human molecules that are involved in infection of human cells.
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Researchers to develop a new method for preserving microbial samples
The project aims to develop a new method for preserving microbial samples without refrigeration/cooling requirements through integrating innovations in microfluidics, biomaterials, protein engineering, and synthetic biology.
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New method sheds light on early cellular and metabolic evolution
Researchers have developed a pioneering method of analysis to investigate microfossils, by fixing them onto a specially coated glass slide (ITO-glass), allowing for integrated observations using both optical and electron microscopy.
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Low-power laser can selectively detect coronavirus spike proteins in just five minutes
Researchers have demonstrated a method to detect the presence of viruses quickly, using only a small sample. The light-induced immunoassay coated with novel coronavirus spike proteins was highly sensitive even with weak light like a laser pointer.
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Discovery paves the way for antivirals against Ebola virus and its deadly relatives
The first detailed, complete images of the Ebola virus nucleocapsid may accelerate the development of antivirals to combat several filoviruses at once.
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Researchers take power and efficiency of biological sensing to record level
Scientists have developed a new biological sensing method that can detect substances at the zeptomolar level – an astonishingly miniscule amount.
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Careers
Caleb investigates the potential for wastewater surveillance of yellow fever virus in his Summer Placement
Second year medical student Caleb Morin reveals what happened during his Applied Microbiology International-sponsored Summer Placement at the University of Galway investigating wastewater surveillance for monitoring yellow fever virus.
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Tiny heroes and innovative technology can fight back against antibiotic-resistant biofilms
Researchers show that antibiotic-infused silver nanoparticles can effectively break down biofilms and also unveil a new sensing method to assess antimicrobial activity.
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Infrared light can pick out biomolecules in living cells
To accelerate biotechnology innovations, such as the development of lifesaving drug therapies, scientists strive to develop faster, more quantitative and more widely available ways to observe biomolecules in living cells. Source: Y. Lee/NIST An image of biomolecules, such as nucleic acids, lipids and proteins, in live cells ...
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Scientists deploy sound waves as acoustic tweezers to separate viruses from saliva
Researchers have described a platform that uses sound waves as acoustic tweezers to sort viruses from other compounds in a liquid. In demonstrations, the method quickly and accurately separates viruses from large and small particles in human saliva samples.
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AI spots cancer and viral infections at nanoscale precision
Scientists have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.
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New high-throughput method reveals the mysteries within microbial genomes
A new technique developed at Lawrence Berkeley National Laboratory (Berkeley Lab) will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species. Source: CDC/ Dr. V. ...
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New genetic editing technique could modify wild populations with less risk
A new technique developed by researchers from Macquarie University and the California Institute of Technology described in Nature Communications on 13 August could allow scientists to more simply and controllably alter the genetic makeup of wild populations than with the use of gene-drives. Coral in Nagoya Aquarium Japan. ...
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Breakthrough in nanotechnology: Viewing the invisible with advanced microscopy
Scientists have developed a novel microscopy method that allows for the unprecedented visualization of nanostructures and their optical properties.
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New technique offers insights into the complexities of chronic Hepatitis B infection
A new technique called spatial transcriptomics is used to gain a deeper understanding of the interplay between chronic hepatitis B (CHB) infection and the immune system within the liver, paving the way for developing novel therapeutic strategies.