All Microbiological Methods articles
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The very first structural images of a tuberculosis-fighting virus
Scientists have used advanced imaging techniques to provide a detailed look at how a tiny virus, known as a phage, invades Mycobacteria. The research could pave the way toward phage-based treatments for antibiotic-resistant mycobacteria.
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Researchers develop UV and machine learning-aided method to detect microbial contamination in cell cultures
This is the first novel technology that utilises machine learning to analyse unique ultraviolet light “fingerprints” on cell cultures to quickly identify the presence of contamination.
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New tool for cutting DNA offers promising prospects for biotechnology
Researchers have developed a new genetic tool based on a family of specific enzymes called Ssn that allows targeted cuts to be induced exclusively in single-stranded DNA. They focused on one of these enzymes in the bacterium Neisseria meningitidis.
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New platform leverages AI and quantum computing to predict salmonella antimicrobial resistance
A recent study presents a novel approach to predict Salmonella antimicrobial resistance, a growing concern for public health. The research combines large language models (LLMs) and quantum computing to develop a predictive platform.
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Scientists develop special agar for isolation of Escherichia albertii and its evaluation with food samples
Scientists have developed a novel E. albertii selective differential medium, XRM-MacConkey medium containing cefixime, tellurite, phosphate, and soy peptone, which differentiates E. albertii (colorless) from E. coli (red) by colony color.
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Microscopy reveals signs of life in earth’s extremes, boosting search for alien life
Researchers used advanced microscopy to detect microbial biosignatures that help to identify the signs of life in extreme environments on Earth, thus also applicable in the search of life in extraterrestial environments.
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Singapore launches national standard to validate antimicrobial disinfectant products
SS 705 provides a first-of-its-kind Singapore-developed assessment to test the effectiveness of antibacterial, antifungal and antiviral potency, as well as durability of surface disinfectants and coatings.
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Hidden signals in water reveal disease early in tomato plants
Researchers have developed an innovative method for the early detection of Fusarium wilt in tomato plants by monitoring subtle changes in the plants’ water use.
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Rice research team creates universal RNA barcoding system for tracking gene transfer in bacteria
An interdisciplinary group of researchers at Rice University has developed an innovative RNA “barcoding” method to track gene transfer in microbial communities, providing new insights into how genes move across species.
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New method uncovers dynamic microbial community in coastal sediments
Scientists utilises single celll genomics and cell staining approaches to investigate the respiratory rates and metabolic activities of the diverse microbial communities in low biomass aqautic environments, such as Maine’s coastal sediments.
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Microbiome: Researchers improve bacterial analysis for clinical applications
Different extraction methods can obtain the DNA of certain bacterial species differently, which can significantly distort the determined microbiome composition. Scientists have developed a computer-based method for correcting extraction bias.
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TB vaccine candidate provides ‘elite’ protection
A tuberculosis vaccine candidate under development shows complete protection and superior immune response in nonhuman primates compared to the existing BCG vaccine.
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Damaged but not defeated: Bacteria use nano-spearguns to retaliate against attacks
Scientists used state-of-the-art microscopy technology to mimic a nano-speargun, the type VII secretion system, used as a bacterial pinpoint counterattack tactic in response to cell envelope damage against rival bacteria.
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Scientists reveal anti-bacterial role of plant metabolite
A study shows that a plant metabolite, erucamide, is able to target and disrupt a protein assembly of Gram-negative bacterial pathogens, thus inhibiting their virulence. Understanding the metabolite’s molecular mechanisms could protect crops from infection.
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Scientists track pneumonia-causing bacteria as they infect the blood stream
A new study has shown various dissemination patterns can be adopted by Klebsiella pneumoniae that causes systemic infection, i.e. bacteremia.
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A rapid and reproducible method for generating germ-free Drosophila melanogaster
Scientists have introduced a refined method for the production of germ-free Drosophila, complemented by a straightforward verification process to ascertain its efficacy.
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Lung abnormalities seen in children and teens with long COVID
An advanced type of MRI uncovers significant lung abnormalities in children and adolescents with long COVID, according to a new study. PREFUL MRI doesn’t require the use of radiation or intravenous contrast agents and can be done while the patient breathes freely.
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Laser-powered device tested on Earth could help us detect microbial fossils on Mars
Scientists hoping to identify fossil evidence of ancient Martian microbial life have now found a way to test their hypothesis, proving they can detect the fossils of microbes in gypsum samples that are a close analogy to sulfate rocks on Mars.
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Nitrogen fixation on marine snow particles is widespread in the world's oceans
Researchers have shown that bacteria attached to marine snow particles can fix N2 over a wide range of temperatures in the global oceans, from the tropics to the poles, and from the surface to the abyss, accounting for about 10% of the overall N2 fixation in oceans.
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Scottish bio-tech company secures £3.4m investment
Scottish biotech engineering company uFraction8 has secured £3.4m in new investment following the completion of a funding round led by Foresight Group.