All Microbial Genomics articles – Page 4
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NewsAspergillus fumigatus adapts to life in humans - and shapes their lung microbiome
Aspergillus fumigatus strains that infect humans have a significantly altered metabolism compared to other strains in the environment. At the same time, infection with the fungus leads to an apparent change in the human lung microbiome. Source: CDC Photomicrograph revealing ultrastructural morphology exhibited by the fungal organism Aspergillus ...
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CareersUncovering the secrets of the mummy
To his great surprise, microbiologist Frank Maixner found himself turning his scientific skills to mummy research. He reveals what the latest techniques are revealing about ancient humans, the history of malaria and the Medici family.
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NewsFly toolkit created for investigating COVID-19 infection mechanisms
A new ‘fly-to-bedside’ resource offers a shortcut for developing drug therapies needed for long COVID and future coronavirus outbreaks.
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NewsDiscovery of new gene unveils sex determination in green algae
Scientists determine how female and male reproductive cells develop in volvocine algae.
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NewsNew CRISPR gene editing approach opens up more of the genome
Scietnists have come up with a new way to identify diverse CRISPR RNA variants that can specifically home in on challenging areas of DNA to target for editing. The new approach opens up more of the genome for editing, enabling the repair of mutations associated with more diseases.
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NewsCRISPR-like system in eukaryotes can edit the human genome
The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.
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NewsMapping evolution of E. coli virulence factor offers refined drug target
Researchers have presented evidence that targeting the K1 capsule can be used as the basis of treatment, paving the way to prevent serious E. coli infections.
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NewsSecond gene implicated in malaria chloroquine resistance evolution
How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, scientists have shown a second key gene is also involved in malaria’s resistance to the drug chloroquine.
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NewsFitness landscape explains Covid variant origins
Researchers have uncovered the mechanisms behind the emergence of new and dangerous coronavirus variants, such as Alpha, Delta, Omicron, and others.
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NewsHIV targeted with novel dual gene-editing approach
Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection, new research shows.
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NewsCRISPR pioneers invent cutting-edge genome edit tool
The team that first discovered the CRISPR loci has now developed a new genome engineering tool that tackles some of the limitations of the most popular CRISPR-based tools.
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NewsMachine learning helps to ID microbe preferences
Researchers have figured out a way to predict bacteria’s environmental pH preferences from a quick look at their genomes, using machine learning.
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NewsNew method may harness radiation-resistant bacterium
Researchers find a novel way to expand applications of the hardy bacterium Deinococcus radiodurans, using gene deletion techniques.
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NewsGenomic surveillance may track evolution of emerging wheat disease fungus
Genomic surveillance may be an effective disease management tool against the wheat blast pandemic, with the ability to trace lineages of emerging crop diseases, and to identify genetic traits for breeding disease-resistant lines, a study suggests.
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NewsMicrobes that “eat together” may benefit from a shared immunological memory
A new study examines viruses that infect microbes in the deep sea and finds evidence that viruses interact with a far more diverse set of hosts than was previously thought.
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NewsScientists reveal how getting physical can tackle a key hurdle in synthetic biology
A team of scientists may have solved one of the biggest hurdles standing in the way of synthetic biology - the difficulty of transferring the resulting large DNA molecules into bacterial host cells.
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NewsMethanogen genomes reveal how life thrives in extreme conditions
A comparison of the genomes of methane-producing microorganisms reveals that temperature adaptation might not be genomically encoded, but rather enforced through protein regulation and finer scale adaptations in amino acids.
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NewsmNGS outperforms microbiological tests to diagnose bloodstream infections
Next-generation sequencing (mNGS) leverages genetic testing advantage to save more lives and is found to be twice as effective at identifying infection cases.
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Long ReadsA relationship with benefits: microfungi’s important role in plant health
Explore the work being done at Royal Botanic Gardens, Kew on the fungi associated with soil, seeds and plants and the future of fungal research.
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NewsUbiquitin protein may be Achilles heel of the flu virus
Researchers have found a trove of potential active ingredients that could help to provide treatment for the influenza virus in the future.