All Medical Microbiology articles – Page 11
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News
Oral probiotic can treat dry eye disease
Researchers have found that oral administration of a commercially available probiotic bacterial strain improved dry eye disease in an animal model.
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Treatment with enzyme inhibitor can help combat antimicrobial resistance
Researchers have shown that intravenous treatment with MK-3402, a metallo-beta-lactamase inhibitor, can be an effective strategy in fighting antimicrobial resistance.
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Mapping evolution of E. coli virulence factor offers refined drug target
Researchers have presented evidence that targeting the K1 capsule can be used as the basis of treatment, paving the way to prevent serious E. coli infections.
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High-throughput method screens protein-secreting microbial strains
A unique method to screen large-scale libraries for industrially useful bacterial strains was recently developed, combining biosensors and microfluidics to quickly identify mutant strains that secrete large amounts of industrially useful proteins.
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Ultrasound helps break bacterial barriers in chronic treatment-resistant wounds
Researchers have developed a new strategy combining palmitoleic acid, gentamicin, and non-invasive ultrasound to improve drug-delivery into chronic wound infections.
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Postal HPV kits boost cervical screening uptake
At-home high-risk human papillomavirus (hrHPV) sampling kits can help increase cervical cancer screening among under-screened women from low-income backgrounds, according to findings from a US-based clinical trial.
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Tobacco plant engineered to act as drug factory
Researchers have engineered a close relative of tobacco, Nicotiana benthamiana, to churn out peptides with antibiotic activity against some of the nastiest pathogens known to medicine.
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Laser breathalyzer sniffs out COVID in real time
Scientists have made an important leap forward in the quest to diagnose disease using exhaled breath, reporting that a new laser-based breathalyzer powered by artificial intelligence (AI) can detect COVID-19 in real-time with excellent accuracy.
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Phage delivers double whammy against biofilms
A novel bacteriophage isolated from sewage water not only kills its target bacteria in the Klebsiella oxytoca complex but was unexpectedly found to be capable of disrupting biofilms produced by these bacteria.
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New biologic effective against major infection in early tests
Researchers have shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus – a bacterial species widely resistant to antibiotics and a major cause of death in hospitalized patients.
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Careers
The paths that made us: Learning to be grateful for the moments that made us who we are
Gloom and dark clouds have veiled the way at times, but I am grateful for where my alternative path has led me - miles from anything I could have pictured, but still a place of joy and love.
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Infectious SARS-CoV-2 isolated from hospital air samples
Scientists have succeeded in isolating infectious particles of the SARS-CoV-2 virus from air samples collected from hospital rooms of COVID-19 patients and kept frozen for more than a year, a new study shows.
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‘Antibiotic culture’ permeates US hospital ICUs, study finds
A new study reveals that there continues to be an ’antibiotic culture’ in US hospitals, meaning that the preference for antibiotics is related to their perceived role as ’magic bullets’.
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Vesicles produced by intestinal bacteria cause a malignant cycle in patients with cirrhosis
Researchers have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as well as reduction of serum albumin level, subsequently leading to oedema and ascites.
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WARNING - GRAPHIC IMAGES: War in Ukraine fuelling rise in injuries infected with multi-drug resistant bacteria
New research being presented at this year’s ECCMID highlights the devastating impact of war injuries with complex bone and soft-tissue multidrug-resistant infections suffered by 13 civilians and one soldier during the war in Ukraine, who were transferred to Germany for specialist treatment.
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Engineered E. coli delivers therapeutic nanobodies to the gut
A genetically modified beneficial strain of bacteria blocks intestinal inflammation in a preclinical model of inflammatory bowel disease and has the potential to treat intestinal-based diseases.
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Researchers ID plant-based compound that inhibits reactivation of the HIV viral reservoir
Researchers have zeroed in on a promising compound that targets HIV reservoirs that persist in people living with HIV despite the presence of anti-HIV therapy.
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Scientists developing drug candidates that could prevent germination of C diff
New research could lead to a drug that susceptible people take before infection starts.
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Novel 2D ultrasound-responsive antibacterial nano-sheets tackle MRSA bone tissue infection
A research team has invented a non-invasive and non-antibiotics technology to effectively reduce methicillin-resistant Staphylococcus aureus (MRSA) infection in bony tissue.
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mNGS outperforms microbiological tests to diagnose bloodstream infections
Next-generation sequencing (mNGS) leverages genetic testing advantage to save more lives and is found to be twice as effective at identifying infection cases.