All Medical Microbiology articles
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NewsSome gut bacteria could make certain drugs less effective
Researchers discovered that gut bacteria can metabolize oral administered drugs that target G protein-coupled receptor (GPCR) and potentially other chemicals and food compounds, leading to impacts on the effectiveness of medication to patients.
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NewsSurgical fixation for infected sites in pyogenic spondylodiscitis inhibits bone destruction and promotes healing
Pyogenic spondylodiscitis is caused by bacterial infections of the spine and intervertebral discs. Researchers investigated how osterior fixation, in which the normal spine is fixed with pedicle screws and rods to stabilize the infected site, suppresses infection.
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NewsThe gut microbiota-metabolites-brain axis mediates social behavior dysfunction following anaesthesia
New research shows that the anaesthetic Sevoflurane (Sev) influences social functioning via the gut-brain axis, with microbiota-derived bile acids serving as critical mediators in this pathway.
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NewsEvaluating DNA impurities in recombinant adeno-associated virus
A new study indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as single-stranded DNA.
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NewsAntibody-based therapy is several steps closer to treat lethal mucormycosis
A new paper discusses the use of monoclonal antibodies to target a key fungal cell surface protein, CotH, which enables the Mucorales fungus to invade human cells and cause mucormycosis, which has high mortality rates in people with weakened immune systems.
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NewsSelective G6PDH inactivation for Helicobacter pylori eradication with transformed polysulfide
A new study highlights a novel mechanism of action driven by polysulfides, presenting a promising alternative strategy for combating H. pylori infections.
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NewsMcMaster leads Canada’s first-ever guidelines for Post COVID-19 Condition
A team of experts from McMaster University has led the creation of Canada’s first-ever comprehensive guidelines for diagnosing, managing, preventing, and treating post COVID-19 condition (PCC), more commonly known as long COVID.
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NewsFour advances that could change tuberculosis treatment
World Tuberculosis Day commemorates Robert Koch’s discovery of the source bacterium Mycobacterium tuberculosis. Scientists are still refining TB diagnosis methods and treatment strategies - some of the latest innovations are revealed here.
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NewsBacteria invade brain after implanting medical devices
Researchers have discovered that bacteria can invade the brain after a medical device is implanted, contributing to inflammation and reducing the device’s long-term effectiveness.
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NewsImmature platelet fraction offers clinical predictor for enhanced platelet recovery in patients with dengue fever
Immature platelet fraction (IPF) is recognized as a marker for thrombopoiesis, but a new study indicates that IPF% can be utilized as a predictor of platelet increase in patients with dengue infection.
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NewsMagnetic microalgae on a mission to become robots
A team of researchers has developed a green algae-based biohybrid micro swimmer covered with magnetic material, whose swimming ability is largely unaffected by the coating.
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NewsHelicobacter pylori treatment practices in the Asia-Pacific region
Researchers conducted an online survey of clinicians in the Asia-Pacific region to investigate treatment policies for H. pylori and confirmed that there is a growing consensus of the importance of primary and secondary prevention against H. pylori.
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NewsEpstein-Barr virus worsens ulcerative colitis by triggering macrophage pyroptosis through glycolysis
The study shows that EBV infection activates pyroptosis in intestinal macrophages by upregulating glycolysis. This process leads to the release of pro-inflammatory cytokines, which further damage the intestinal barrier and worsen colitis symptoms.
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NewsCOVID-19 pandemic worsened mother and infant birth outcomes
Mothers who became pregnant after the start of the pandemic, those who experienced moderate-to-severe infections during pregnancy, and those who had infections during the third trimester were more likely to have adverse outcomes.
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NewsSymptoms of long-COVID can last up to two years after infection with COVID-19
According to a study of the COVICAT cohort, almost one in four people infected with SARS-CoV-2 suffered from long-COVID. In more than half of them the symptoms persisted for two years.
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NewsA*STAR spin-off NalaGenetics implements nationwide drug reaction screening for leprosy patients in Indonesia
NalaGenetics, a spin-off from A*STAR Genome Institute of Singapore (A*STAR GIS), will be transforming leprosy treatments in Indonesia with a nationwide genetic screening programme with their PGx1301 diagnostic kit.
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NewsLung abnormalities seen in children and teens with long COVID
An advanced type of MRI uncovers significant lung abnormalities in children and adolescents with long COVID, according to a new study. PREFUL MRI doesn’t require the use of radiation or intravenous contrast agents and can be done while the patient breathes freely.
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NewsNew paper-based device boosts HIV test accuracy from dried blood samples
Scientists have trialled a more precise medical device to measure HIV viral loads by engineering a paper device with wax-printed patterns that create precise channels and collection spots, ensuring it consistently collects the same volume of blood.
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NewsPaxlovid’s impact on hospitalization and death in COVID-vaccinated older adults far weaker than previously thought
A new study overturns the assumption that Paxlovid’s effectiveness in reducing COVID-19 hospitalizations and deaths in unvaccinated adults also applies to vaccinated adults.
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NewsNovel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.