All Lung Microbiome articles
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NewsA lung pathogen’s dilemma: infect or resist antibiotics?
Research has uncovered how Pseudomonas aeruginosa manages the trade-off between colonizing and surviving during infection by switching between biofilm formation for antibiotic protection and a more mobile, “planktonic” state to spread and access nutrients.
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News$7 Million grant to tackle lung infections through innovative probiotic treatment
The PROTECT project seeks to combat lung infections by assembling a community of beneficial lung microbes that can outcompete harmful pathogens.
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NewsNIH grant establishes UAB’s Global Research Resource for Human Tuberculosis
A $5.8m grant led by Adrie Steyn, Ph.D., of the University of Alabama at Birmingham and the Africa Health Research Institute, or AHRI, in Durban, South Africa, will provide user-requested infected human lung tissue and analytical services to tuberculosis researchers worldwide.
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NewsRecurrent wheezing in children linked to ‘silent’ lung infections
Nearly a quarter of children with recurrent wheezing have “silent” lung infections without symptoms, new research reveals. That finding could have big effects on how the condition is treated.
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NewsCancer drug could be repurposed to fight Covid-19
Twelve years ago, cancer researchers identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue. In new research, they show that the same molecule does the same thing in lung tissue infected with COVID-19.
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NewsTwo types of polymicrobial infections in chronic lung diseases
Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study team led by MedUni Vienna has identified two types of these so-called dysbioses in cystic fibrosis. They display distinct ecology and are also likely to respond differently to treatment. The study was published in the journal ...
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NewsLung organoids unveil secret of how pathogens infect human lung tissue
Using human lung microtissues, researchers have uncovered the strategy used by a dangerous pathogen to invade the lungs. Pseudomonas aeruginosa targets specific lung cells and has developed a sophisticated strategy to break through the lungs’ line of defense.
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NewsLung microbiomes predict mortality in children following bone marrow transplant
Using a method that identifies all potentially pathogenic organisms present in the lungs, scientists have discovered links between certain microbial communities and the relative risk of mortality in children who undergo bone marrow transplants.
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NewsGroundbreaking clinical trial evaluates oncolytic virus for non-small cell lung cancer
Moffitt Cancer Center has launched a pioneering clinical trial for patients with late-stage non-small cell lung cancer, using a novel oncolytic virus, MEM-288, in combination with the immune checkpoint inhibitor nivolumab.
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NewsResearchers uncover new reasons to target neutrophils for tuberculosis therapy
Using cell models of infection, scientists examined the cross-talk between two lung immune cells: the macrophage and the neutrophil.
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NewsAntibiotics aren’t effective for most lower tract respiratory infections
Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment for lower-respiratory tract infections.
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News Tuberculosis can have a lasting impact on the lung health of individuals who have been successfully treated for the disease
New research has found compelling evidence that tuberculosis (TB) can have a lasting impact on the lungs of individuals who have been successfully treated for the disease.
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NewsNewborn piglets serve as a model for studying influenza
A multidisciplinary team of researchers has studied newborn piglets to better understand the progression of influenza infections.
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NewsStudy shows important role gut microbes play in airway health in persons with cystic fibrosis
Findings from a new study conducted by a team of researchers at Dartmouth’s Geisel School of Medicine and published in the journal mBio, reflect the important role that the gut microbiome (communities of bacteria) plays in the airway health of persons with cystic fibrosis. Source: CDC/ Dr. ...
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NewsSevere lung damage caused when flu is followed by infection with measles-like virus
Infection with a measles-like virus causes catastrophic lung failure in ferrets previously infected with influenza virus or respiratory syncytial virus, according to a new study.
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NewsBacteria in the mouth linked to pulmonary fibrosis survival
Bacteria in the mouth may play a role in survival from idiopathic pulmonary fibrosis (IPF), a new study finds.
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NewsStudy uncovers how gum disease aggravates COPD
A new study shows how periodontitis, an oral disease, activates immune cells associated with aggravated progression of COPD.
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NewsOmicron induces cellular senescence in human lung, study finds
Researchers investigating the influence of defined altered spike formations have confirmed that the Omicron variant induces cellular senescence in human lungs of COVID-19 patients.
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NewsStudy reveals how bacteria use snot to swarm and spread infection
New research shows how thicker mucus supercharges bacteria’s ability to self-organize into swarms to spread infection.
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NewsStep forward in understanding how to tackle chronic infections in cystic fibrosis patients
Scientists have engineered a living material resembling human phlegm, which will help them to better understand how a certain kind of infection develops on the lungs of patients with cystic fibrosis.
