All articles by Linda Stewart – Page 24
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New research reveals how location influences how our immune system fights disease
Researchers have revealed how cells known as tissue-resident memory CD8 T cells play unique and specialized roles based on where they are located within the small intestine, providing a local first line of defense against re-infection.
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Scientists discover how the gut modulates the development of inflammatory conditions
Scientists have discovered how gut bacteria that cross a weakened intestinal barrier induce changes in bone marrow that strengthen the immune response.
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What microbes tell us about Nonalcoholic Fatty Liver Disease
Using medical data from more than 1,200 people, specific microbiome signatures have been identified that allow precise prediction of Nonalcoholic Fatty Liver Disease (NAFLD).
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Scientists culture previously uncultivable human rhinovirus C with innovative respiratory organoids
Scientists have successfully utilised human respiratory organoids (mini-organs) established by their team to propagate human rhinovirus C (HRV-C), which had previously been refractory to conventional virus cultivation.
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New paper creates roadmap for the next generation of bioelectronic medicine
A new paper offers a roadmap to the future of bioelectronic medicine — which makes use of electrical signals instead of drugs to diagnose and treat disease.
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Towards improved pandemic preparedness: Launch of new EU project COMBINE
A project for the targeted development of antiviral therapies for newly emerging viruses, COMBINE focuses on the critical virus-cell binding step, aiming to identify key factors and potential therapeutic targets involved early in viral infections.
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Scientists synthesize a promising mushroom-derived compound
Researchers have successfully developed the first method to synthesize inaoside A, a compound derived from the edible mushroom Laetiporus cremeiporus.
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Dihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
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Human papillomavirus infection kinetics revealed in new longitudinal study
Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a new study.
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Biotin may shield brain from manganese-induced damage, study finds
New research showing the mechanisms by which manganese inflicts damage to the central nervous system suggests that the vitamin biotin - synthesized by gut bacteria - may have a protective effect, potentially mitigating manganese-induced damage.
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WHO calls on Trump to reconsider order that USA will withdraw from the Organization
The World Health Organization has said it regrets President Donald Trump’s announcement that the United States of America intends to withdraw from the Organization.
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Cycle of coral bleaching on the Great Barrier Reef now at ‘catastrophic’ levels
Marine scientists have published the first peer-reviewed study documenting the devastating coral bleaching events that occurred on the southern Great Barrier Reef in early 2024. 66 per cent of the colonies were bleached by February 2024 and 80 per cent by April.
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Ancient viral DNA shapes early embryo development
Over half of our genomes consists of remnants of ancient viral DNA which are widespread across the tree of life. Once dismissed as the ’dark side’ of the genome, researchers have now revealed the role of transposable elements in early embryo development.
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Valneva reports high sustained immune response in adolescents one year after Chikungunya Vaccine
Valneva SE, a specialty vaccine company, has reported further positive Phase 3 data in adolescents for its single-shot chikungunya virus (CHIKV) vaccine, IXCHIQ®, which showed a sustained 98.3% sero-response rate one-year after single vaccination.
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Tiny vortices help detect dangerous viruses
Due to the specific wavelengths of vibrations used to create these tiny whirlpools, they efficiently trap cells, bacteria and other larger bioparticles found in saliva while leaving antibodies and viruses free to flow forward through multiple biosensing chambers.
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Bacteria in polymers form cables that grow into living gels
Scientists have discovered that bacterial cells growing in a solution of polymers, such as mucus, form long cables that buckle and twist on each other, building a kind of “living Jell-O.”
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Extreme rain heightens E. coli risks for communities of color in Texas
New research shows that communities of color in Texas face pronounced risks of E. coli exposure in nearby waters following storms that dump abnormally high amounts of rain.
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Machinery behind bacterial nanowires discovered
Almost all living things breathe oxygen to eliminate the excess electrons produced when nutrients are converted into energy. However, most microbes that mitigate pollution and climate change don’t have access to oxygen. Instead, these bacteria—buried underground or living deep under oceans—have developed a way to eliminate electrons by “breathing minerals” ...
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Rotavirus protein NSP4 manipulates gastrointestinal disease severity
This study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells.
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Bioactive compounds with possible industrial applications are identified in extremophilic bacteria from the Andes
Researchers isolated a strain of Pseudomonas alcaligenes that can withstand temperatures as high as 44 °C from a hot spring in Chile, and characterized the substances produced by the bacterium that help it survive extreme conditions.