All articles by Linda Stewart – Page 147
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COVID-19 infection alters gene transcription of olfactory mucosal cells in Alzheimer’s disease
A new study identifies alterations in the transcriptomic signatures in human olfactory mucosal cells of individuals with Alzheimer’s disease following SARS-CoV-2 infection, potentially contributing to exacerbated COVID-19 outcomes.
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EMA gives positive opinion to first oral treatment of acute form of sleeping sickness
The EMA Committee for Medicinal Products for Human Use (CHMP) has adopted a positive scientific opinion of Fexinidazole Winthrop as first oral treatment of acute form of sleeping sickness (rhodesiense).
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Omicron induces cellular senescence in human lung, study finds
Researchers investigating the influence of defined altered spike formations have confirmed that the Omicron variant induces cellular senescence in human lungs of COVID-19 patients.
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Microbiome insights found in faeces help predict infections in liver transplant patients
In a new study, researchers at the University of Chicago were able to predict postoperative infections in liver transplant patients by analyzing molecules in their poop. Their analysis represents a key leap forward in exploring the connection between the gut microbiome — the bacteria that inhabit the human body — ...
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Researchers pave way for next generation COVID-19 immunization strategies
A vaccine booster delivered directly to mucosal site of infection enhances protection against COVID-19 infection in non-human primates, a new study reveals.
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New pasteurization method wipes out pathogens on buckwheat sprouting seeds, study shows
A new pasteurization technique uses plasma, vacuum packaging and hot water to inactivate food pathogens on buckwheat seeds, cutting the risk of food poisoning outbreaks without preventing the seeds from sprouting. The technique, which reduces the total time for seed pasteurization,was developed by scientists at Kyonggi University ...
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Risk of death reduces after COVID-19 vaccine but protection wanes after six months
The risk of death from COVID-19 decreases significantly after vaccination but this protection diminishes after six months, providing evidence for continued booster doses, a new study has found.
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Ancient DNA reveals how a chicken virus evolved to become more deadly
Scientists have used ancient DNA to trace the evolution of Marek’s Disease Virus (MDV), showing how viruses evolve to become more virulent and could lead to the development of better ways to treat viral infections.
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Diverse gut bacteria communities protect against harmful pathogens by nutrient blocking
A new study demonstrates that diverse communities of resident bacteria can protect the human gut from disease-causing microorganisms. However, this protective effect is lost when only single species of gut bacteria are present.
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New understanding of ancient genetic parasite may spur medical breakthroughs
Scientists have published the first high-resolution images and structural details of a virus-like element known as LINE-1, describing it as “an ancient genetic parasite” that is one of the most common parts of human DNA.
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Cockroaches can transmit antimicrobial resistance genes between groups
A new paper describes a study of antimicrobial resistance (AMR) transmission among cockroaches, with implications for AMR transmission in humans.
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Breastfeeding alters infant gut in ways that boost brain development, may improve test scores
A study of the infant ‘fecal metabolome’ suggests that nursing, including part-time while supplementing with formula, yields significant brain-health benefits.
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Gut bacteria of malnourished children benefit from key elements in therapeutic food
Researchers investigating a new therapeutic food aimed at repairing malnourished children’s underdeveloped gut microbiomes has identified key, naturally occurring biochemical components and the important bacterial strains that process these components.
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3G microbial cell factories: achieving sustainable goals with engineered microorganisms
Scientists review the progress made in the development of artificial biological systems for 3G refineries over the last decade.
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Scientists reveal rare enzyme role change with bacterial defense system assembly
A never-before-seen phenomenon in a protein: alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
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Making probiotics more widely applicable through ‘CRISPR’ engineering
Scientists review the recent progress and challenges in the production and use of genetically modified probiotics.
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Infection with stomach bacteria may increase risk of Alzheimer’s disease
Infection with the stomach bacterium Helicobacter pylori could increase the risk of developing Alzheimer’s disease. In people over the age of 50, the risk following a symptomatic infection can be an average of 11 per cent higher.
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Dr Thomas Thompson named as winner of inaugural John Snow Prize
Dr Thomas Thompson of Queen’s University Belfast in Northern Ireland has been named as this year’s winner of the inaugural John Snow Prize for microbiology. The prize is part of the Applied Microbiology International Horizon Awards, which celebrate the brightest minds in the field and promote the ...
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€20 million EIB venture debt financing to support microbiome research and development
The EIB has signed €20 million in venture debt financing with Belgian microbiome health company The Akkermansia Company to accelerate the R&D and commercial activities around the Akkermansia muciniphila bacterium.
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Mpox vaccine triggers equally strong immune response in smaller doses
Delivering the two-dose mpox vaccine in smaller than the usual FDA-approved doses produced a detectable immune response. This also occurred regardless of whether people were living with or without HIV.