Latest News in WAAW – Page 3
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Bacterial gut diversity improves the athletic performance of racehorses
The composition of gut bacteria of thoroughbred racehorses at one-month-old can predict their future athletic performance, according to a new study.
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Researchers discover new Candida auris – a possible global public health threat
Researchers have discovered a new clade (or type) of Candida auris, bringing the number of clades known globally to a total of six.
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Researchers discover source of deadly fungal infections in bone marrow transplant patients
Scientists have found that heteroresistance is the reason a small number of transplant patients developed bloodstream infections, despite receiving prophylaxis with the antifungal drug micafungin.
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Scientists solve mystery of bacterial scavenging machinery
Scientists investigated how the oleate shuttle from FakB2 to FakA kinase works in the Fak system, which is exploited by the zoonotic pathogen Streptococcus suis (S. suis) pathogen to scavenge exogenous fatty acid (eFA).
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Coinfecting viruses impede each other’s ability to enter cells
Scientists researching phage infection at the level of a single cell investigated whether the number of infecting phages that bind to the bacterial surface corresponds to the amount of viral genetic material that is injected into the cell.
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Super cally molecules take down tuberculosis
Researchers have identified and synthesised a group of molecules that can act against the cause of tuberculosis in a new way. The callyaerins act against TB by employing a fundamentally different mechanism compared to antibiotic agents used to date.
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New compound found to be effective against flesh-eating bacteria
Researchers have developed a novel compound that effectively clears bacterial infections in mice, including those that can result in rare but potentially fatal ‘flesh-eating’ illnesses, and could be the first of an entirely new class of antibiotics.
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Human clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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Copper oxide nanoparticles to counter pathogens are synthesized from mango
Researchers have synthesized green copper oxide nanoparticles from Mangifera indica leaf extract. They showed potent activity against gram-positive and negative bacteria, as well as fungicidal effects on persimmon fruit pathogens.
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AI opens door to safe, effective new antibiotics to combat resistant bacteria
A large language model—an AI tool like the one that powers ChatGPT—has been used to engineer a version of a bacteria-killing drug that was previously toxic in humans.
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Derivative of the long pepper battles bacterial biofilms
Scientists investigating the long pepper - known in traditional medicine for its treatment of a variety of illnesses - have created a derivative that disrupts bacterial chemical communication.
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Dual action antibiotic could make bacterial resistance nearly impossible
A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to new research
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New agent effective against drug-resistant malaria parasites
Scientists have developed a promising new antimalarial agent, DIF-1(+3), which is a derivative of Dictyostelium differentiation-inducing factor-1 (DIF-1).
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New UK research networks will tackle antimicrobial resistance
Eight new UK networks, combining different research specialisms, will work together to tackle one of humanity’s biggest threats, antimicrobial resistance (AMR).
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AMAST Network launches to battle AMR in the agrifood system
AMAST – the AMR in Agrifood Systems Transdisciplinary Network, has been created to harness perspectives from across agrifood stakeholders and prepare new ways to tackle these challenges.
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Peptide cocktails could be key to fighting antibiotic resistance
A new study highlights the potential of random antimicrobial peptide mixtures to significantly reduce the risk of resistance evolution compared to single peptides, emphasizing the need for innovative solutions to outpace bacterial resistance and safeguard health.
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Scientists identify possible new transmission factor in hospital-acquired Klebsiella infections
The dangerous multidrug resistant (MDR) pathogen, Klebsiella, thrives under nutrient-deprived polymicrobial community conditions found in hospital environments, a new study reveals.
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Surgical Infection Society issues new guidelines on the management of intra-abdominal infection
The Surgical Infection Society (SIS) has presented new evidence-based guidelines for the management of intra-abdominal infection (IAI) in the peer-reviewed journal Surgical Infections. “These guidelines are critical in the ongoing work by the Surgical Infection Society to decrease the number of deaths from the most common ...
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Rising antimicrobial resistance in some Salmonella serovars isolated from retail chicken meat
Salmonella infections are a major public health issue in the United States, causing over 1.3 million illnesses annually. These infections are a leading cause of foodborne illness, often traced back to raw or undercooked poultry meat and eggs. Source: National Institute of Allergy and Infectious Diseases Scanning electron ...
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Researchers unveil secrets behind phages’ flawless timing
New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.