Latest News in WAAW – Page 10
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Study finds artificial intelligence can develop treatments to prevent superbugs
Researchers developed an AI model that can determine the best combination and timeline to use when prescribing drugs to treat a bacterial infection, based solely on how quickly the bacteria grow given certain perturbations.
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Major genetic meta-analysis reveals how antibiotic resistance in babies varies according to mode of birth, prematurity, and where they live
Meta-analysis of genetic studies from 10 countries finds infants born by C-section have more antibiotic resistance genes; antibiotic use and prematurity also fuel resistance.
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Climate change is multiplying the threat caused by antimicrobial resistance
Climate change is multiplying the threat caused by antimicrobial resistance (AMR), amplifying its growing risk through increasing global temperatures, greenhouse gas emissions and rising sea levels, experts have warned.
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Vaccine candidate could fight antibiotic resistance
Scientists have announced several discoveries that will help the development of a carbohydrate-based vaccine for infections caused by Staphylococcus aureus and its “superbug” relative methicillin-resistant Staphylococcus aureus, or MRSA.
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Salmonella rates more prevalent in commercial poultry farm samples vs backyard farms
In a comparison of differently sized poultry farms, researchers at North Carolina State University found that rates of Salmonella in fecal and environmental samples were more prevalent on larger commercial farms than on smaller backyard farms.
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Optimal timing maximises Paxlovid benefits for treating COVID-19
Study suggests using the anti-COVID-19 treatment Paxlovid three to five days after symptoms emerge in patients and expanding global access to the drug may help reduce the severity and transmission of the SARS-CoV-2 virus.
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Odor-causing bacteria in armpits targeted using bacteriophage-derived lysin
Researchers analyzed bacterial metabolism and the DNA of skin microflora in armpit fluid samples and found odor-causing precursors along with a proliferation of Staphylococcus hominis bacteria.
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Gut bacteria can change their ‘software’ in reaction to inflammation
New research reveals an ingenious adaptation strategy used by gut microbes, allowing them to dynamically reprogram gene expression based on local conditions like inflammation or viral attacks.
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Rise seen in use of antibiotics for conditions they can’t treat – including COVID-19
A five-year trend study shows a rebound in inappropriate use after an early-pandemic dip, and a need to tackle overuse in all patients during viral illness outbreaks.
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Black women hospitalised in USA with blood infection resistant to last-resort antibiotic at increased risk of death
New research finds that the odds of death in black women with a bloodstream infection (BSI) caused by carbapenem-resistant enterobacterales (CRE) was twice that of black men or white women.
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Longest known SARS-CoV-2 infection of 613 days led to unique highly mutated variant
New research to be presented at next week’s ESCMID Global Congress highlights the risk of new immune-evasive SARS-CoV-2 variants emerging in immunocompromised patients.
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New class of antimicrobials discovered in soil bacteria
Scientists have mined Streptomyces for antibiotics for nearly a century, but the newly identified umbrella toxin escaped notice.
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Probiotic feed additive boosts growth and health in poultry in place of antibiotics
Researchers found that supplementing the diet of young chicks with a probiotic over 21 days significantly boosted the abundance of beneficial intestinal microorganisms.
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Copper beads in pig feed reshape swine gut microbiome
New findings show copper beads influence the microbial makeup in a pig’s gut, but more work is needed to optimize the benefits.
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Nanoparticle enhances antibacterial sonodynamic therapy for eradication of Pseudomonas aeruginosa biofilm
A novel ultrasound-launched targeted nanoparticle was developed to universally destroy biofilm, target bacteria, deliver antibiotics, and efficiently kill bacteria via ultrasonic cavitation and antibacterial sonodynamic therapy.
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Researchers resolve old mystery of how phages disarm pathogenic bacteria
Scientists observed how a phage called PP7 infects Pseudomonas aeruginosa by attaching to the pilus, which then retracts and pulls the phage to the cell surface.
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Antibiotics aren’t effective for most lower tract respiratory infections
Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment for lower-respiratory tract infections.
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Study confirms how RNA chemical modifications benefit HIV-1
A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus’s ability to survive and thrive after infecting host cells, a new study has found.
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Innovative antiviral defense with new CRISPR tool
Scientists outline how they have overcome a significant obstacle that has hampered the effectiveness of Cas13d: its restriction to the nucleus of mammalian cells.
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Biofilms play key role in reducing sensitivity to ionic silver in wound pathogens.
Bacterial pathogens in wounds that have been treated with ionic silver can adapt and become less sensitive - thanks to biofilm formation.