All itraconazole articles
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NewsAgricultural azoles drive clinical azole resistance in Candida tropicalis via inducing aneuploidy
To define the causal role of agricultural azole fungicides in driving clinical azole resistance in the major human opportunistic fungal pathogen Candida tropicalis, researchers conducted a systematic study integrating experimental evolution, genomic characterization, and transcriptomic profiling.
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NewsUncovering the shield: gene duplication behind antifungal resistance in Madurella fahalii
Researchers used advanced genetic and biomolecular chemistry tools to uncover why itraconazole treatment fails against Madurella fahalii but not other Madurella species.
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NewsBone loss drugs can help azoles fight fungal infections
A new study suggests that adding common bone loss drugs to azoles can improve efficacy. In lab tests, combinations of these drugs worked against dermatophyte species and prevented resistance.
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NewsStatins team up with azoles to battle fungal infections
Researchers evaluated the antifungal efficacy of the pitavastatin-azole combination in silkworm models, suggesting its potential as an effective clinical treatment.