All Innovation News articles – Page 3
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Researchers develop first-of-its-kind RNA tool to advance cancer and infectious disease research and treatment
Scientists have developed a powerful tool capable of scanning thousands of biological samples to detect transfer ribonucleic acid (tRNA) modifications — tiny chemical changes to RNA molecules that help control how cells grow, adapt to stress and respond to diseases such as cancer and antibiotic‑resistant infections.
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Therapeutic vaccination against HPV-related tumors: Nanoparticles make the difference
Researchers have developed a therapeutic vaccination concept that can mobilize the immune system to target cancer cells. Virus peptides coupled to silica nanoparticles can elicit effective T-cell responses against HPV-related tumors. In a mouse model, the nanoparticle-based vaccine was able to partially or completely suppress HPV-related tumors.
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New pimple patches deliver a powerful remedy to unwanted zits
Researchers have designed a two-stage pimple patch set with an array of tiny spikes that grabs onto the pimple and delivers antibacterial or anti-inflammatory compounds. Human clinical trials confirmed that the pimples disappeared after seven days of treatment.
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Chronic wound infection model is much closer to real life - and cuts back on animal testing
Thousands of lab animals are used every year to test wound treatments. But one lab in Wales is pointing the way towards a more humane model of research, with the work it is carrying out on in vitro/animal replacement models.
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Researchers use generative AI to design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).
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‘Controlled evolution’ dramatically boosts pDNA production for biomedical manufacturing
Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. pDNA is an essential – and expensive – ingredient in many gene therapies.
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Portable spectroscopy enables detection of vaginal microbes
Surface-enhanced Raman spectroscopy can rapidly and noninvasively detect specific bacterial species in vaginal fluid, enabling early identification of microbiome imbalances.
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Fast, accurate, low-cost diagnostics - and no lab required
Researchers have developed a breakthrough diagnostic tool that could transform how quickly and reliably we detect illnesses like COVID-19, Ebola, AIDS or Lyme disease. The test uses just a single drop of blood, costs a couple of dollars and delivers results in only 15 minutes.
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New hydrogel-based treatment accelerates infected wound healing and balances skin microbiota
A novel ε-poly-L-lysine-loaded sodium-alginate/gelatin hydrogel (PSG15) has shown exceptional promise in accelerating the healing of infected wounds. The injectable hydrogel delivers antibacterial properties while regulating macrophage polarization and stabilizing the skin microbiota.
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Nanoparticles that self-assemble at room temperature could transform vaccine delivery
Researchers have engineered polymer-based nanoparticles that form with a simple temperature shift—no harsh chemicals, no specialized equipment, and no processing needed. They can self-assemble at room temperature and deliver RNA to living cells.
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Disarming a hidden killer: Predicting – and preventing – C. diff before it strikes
Researchers have developed a powerful, personalized modeling framework to predict whether Clostridioides difficile is likely to colonize an individual’s gut, and to test whether specific probiotic therapies might prevent and/or reverse that colonization.
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Anti-neuroinflammatory natural products from isopod-related fungus now accessible via chemical synthesis
Herpotrichone is valued for its ability to suppress inflammation in the brain and protect nerve cells, but could only be obtained in minute quantities from fungi that are symbiotic with isopods. Researchers have succeeded in chemically synthesizing this rare natural product.
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New imaging approach transforms study of bacterial biofilms
Scientists have reimagined the capabilities of atomic force microscopy, transforming it into a tool that captures large-scale biological architecture. This advance offers an unprecedented view of biofilm organization.
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New drug combo outperforms Tamiflu in fighting flu (and chocolate is the key)
Scientists have unveiled a new drug pairing - including a compound found in chocolate - that outperforms Tamiflu, the most widely used anti-influenza medication, against even the deadliest flu strains, including avian and swine flu.
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AUN bacteria herald an immune-independent breakthrough
A joint research team has developed a groundbreaking immune-independent bacterial cancer therapy using a novel microbial consortium called AUN (阿吽), composed of two naturally occurring bacteria: a tumor-resident microbe and photosynthetic bacterium.
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Smart wound monitor poised to improve chronic infection care
Researchers have developed a wearable wound monitoring device with integrated sensors that could reduce infection risks by minimising the need for frequent physical contact.
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Researchers develop bacterial cellulose-based dressing for advanced burn wound care
Scientists have developed an innovative bacterial cellulose (BC)-based hemostatic dressing that enables rapid and sustained bleeding control.
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Two new solutions for coral protection: a conductive biopaste and a natural healing patch
A research group in Italy has developed two new coral protection technologies for healing and restoring coral reefs: a biopaste and a natural patch, both successfully tested on real corals.
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‘Major leap in bioelectronic sensing’: researchers turn bacteria into tiny pollution detectors
Researchers have engineered E. coli to act as living multiplexed sensors, allowing these genetically modified cells to detect and respond to multiple environmental toxins simultaneously by converting their biological responses into readable electrical signals.
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A non-invasive test enables accurate detection of infant meningitis
A high-resolution ultrasound device has shown great accuracy in detecting suspected meningitis in newborns and infants, potentially offering a non-invasive alternative to lumbar puncture, the traditional diagnostic method.