All Innovation News articles – Page 2
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Microbial load can influence disease associations, new model reveals
Scientists have developed a new machine-learning model to predict microbial load — the density of microbes in our guts — and used it to demonstrate how microbial load plays an important role in disease-microbiome associations.
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Scientists exploit shape change to reveal how immune cells sniff out pathogens
Researchers are using an innovative method to watch immune receptors go about their business, based on the fact that cells tend to change their form when they come into contact with a signal molecule.
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One genomic test can diagnose nearly any infection
A genomic test to rapidly detect almost any kind of pathogen – virus, bacteria, fungus or parasite – has proved successful after a decade of use.
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Innovative culture method aerates microbes in static liquid medium without shaking
Culturing is a basic yet indispensable method in microbiology research. Microorganisms are often cultured in a liquid medium that provides essential nutrients, and this process is both simple and highly effective. Source: Prof. Motomu Akita from Kindai University Kindai university researchers devise a new method of culturing microorganisms ...
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New tool enables a more complete and rapid decoding of the language of algal gene expression
A new method that research teams can use to measure and compare different forms of proteins and protein complexes helped reveal a previously unseen molecular signature of how algal genomes are controlled during the cell cycle.
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Full-bodied cheese flavor–prediction of flavor development soon possible thanks to new method
Peptides formed during cheese ripening are crucial for the full-bodied flavor of aged cheeses, known as kokumi. Researchers have now developed a new method to analyze these flavor-relevant peptides precisely, quickly, and efficiently.
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Chemical trick activates antibiotic directly at the pathogen
Scientists have seen promising results after experimenting with a click-to-release approach that deploys a masked form of colistin to the site of an infection so that it is no longer as damaging to the kidneys while maintaining its high antibiotic efficacy.
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New microfluidic chip method developed for sepsis prognosis and evaluation
Researchers have developed a new prognostic evaluation method for sepsis patients using a microfluidic concentration gradient chip.
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AI decodes microbes’ message in milk safety testing approach
DNA sequencing combined with artificial intelligence could detect anomalies that signal trouble in dairy production, researchers report.
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Life-saving spongelike ‘bandage’ rapidly stops hemorrhaging and mitigates risk of infection
Researchers worked together to create a liquid gel that quickly transforms into a spongelike antimicrobial foam to stymie severe bleeding and ultimately preserve lives.
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mRNA vaccines for disease outbreaks can be synthesized in less time with new technique
Researchers have developed an innovative synthesis technology capable of producing high purity, fully chemically synthesized mRNA, cutting out the slower enzyme reactions, which could lead to mitigation of future infections at a preliminary stage.
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Bacterial vaccine shows promise as cancer immunotherapy
Researchers have engineered bacteria as personalized cancer vaccines that activate the immune system to specifically seek out and destroy cancer cells.
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Hospitals that are understaffed for infection prevention and control have higher rates of infection, study says
Inadequate infection prevention and control staffing levels are associated with higher rates of healthcare-associated infections, according to a new study published today in the American Journal of Infection Control. The study, conducted by the APIC Center for Research, Practice & Innovation, summarizes a pilot project to evaluate ...
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Scientists discover series of SARS-CoV-2 mpro inhibitors for potential COVID-19 treatments
New research has identified a novel series of SARS-CoV-2 Mpro inhibitors that may lead to potential new COVID-19 treatments that, according to preclinical testing, effectively inhibits COVID-19 and synergizes with existing anti-COVID therapies.
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Scientists engineer new enzyme to produce synthetic genetic material
Researchers have engineered an efficient new enzyme that can produce a synthetic genetic material called threose nucleic acid. The ability to synthesize artificial chains of TNA advances the discovery of therapeutic options to treat cancer and other diseases.
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Super-strong bacterial cellulose macrofibers made simple with TAT technique
Researchers have engineered a novel method to create high-performance macrofibers with enhanced mechanical properties and humidity response.
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Single-cell genomics decodes bacteria genomes and uncovers new species
A team of researchers has developed a groundbreaking single-cell genome approach. This approach, which reads information from individual cells, offers a promising alternative to conventional metagenomics.
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Scientists can pinpoint bacterial needle in haystack using fluorescence
Bacterial troublemakers are able to survive antibiotics and are not detected by diagnostic antibiotic resistance testing. A new method has been developed to look at single bacteria and to find the antibacterial resistant ones, or the troublemakers, among them.
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Peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
The synthetic peptide was inspired by ACE2, the protein to which the virus that causes COVID-19 binds to invade human cells. The results point to a route for the development of novel antivirals.
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New mouse models offer valuable window into COVID-19 infection
Scientists have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19 because their cells were engineered to include two important human molecules that are involved in infection of human cells.