All Innovation News articles – Page 2
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Researchers develop enhanced method for wastewater surveillance of antibiotic resistance
To better monitor the emergence and spread of antibiotic resistance, researchers have developed a CRISPR-enriched metagenomics method for the enhanced surveillance of antibiotic resistance genes, ARGs, in wastewater.
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Synthetic microbiome therapy suppresses bacterial infection without antibiotics
A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans. Clostridioides difficile is a bacterium that can cause severe diarrhea, abdominal pain and colon inflammation.
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World first clinical trial will study specialized ‘poop pills’ to improve treatment of advanced pancreatic cancer
A world-pioneering fecal microbiota transplantation pill will undergo a clinical trial, aiming to improve immune responses by remodifying the gut microbiome in patients with advance pancreatic cancer.
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New method developed to dramatically enhance bioelectronic sensors
In a breakthrough that could transform bioelectronic sensing, researchers have developed a new method to dramatically enhance the sensitivity of enzymatic and microbial fuel cells using organic electrochemical transistors (OECTs).
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A rapid and reproducible method for generating germ-free Drosophila melanogaster
Scientists have introduced a refined method for the production of germ-free Drosophila, complemented by a straightforward verification process to ascertain its efficacy.
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A*STAR spin-off NalaGenetics implements nationwide drug reaction screening for leprosy patients in Indonesia
NalaGenetics, a spin-off from A*STAR Genome Institute of Singapore (A*STAR GIS), will be transforming leprosy treatments in Indonesia with a nationwide genetic screening programme with their PGx1301 diagnostic kit.
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New paper-based device boosts HIV test accuracy from dried blood samples
Scientists have trialled a more precise medical device to measure HIV viral loads by engineering a paper device with wax-printed patterns that create precise channels and collection spots, ensuring it consistently collects the same volume of blood.
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Laser-powered device tested on Earth could help us detect microbial fossils on Mars
Scientists hoping to identify fossil evidence of ancient Martian microbial life have now found a way to test their hypothesis, proving they can detect the fossils of microbes in gypsum samples that are a close analogy to sulfate rocks on Mars.
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Scientists invent new drug candidates to treat antibiotic-resistant bacteria
Researchers designed a new family of antibiotics that’s a variation of an existing drug called vancomycin, which is used as a last resort for extremely ill patients. The new version of vancomycin targets, bonds to and renders inactive two different parts of a molecule on the surfaces of pathogenic bacteria.
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Machine learning framework can decipher immune system’s record of past infections
A novel machine learning framework can decipher an individual’s immune system’s record of past infections and diseases, providing a powerful tool with the potential for diagnosing autoimmune disorders, viral infections, and vaccine responses with precision.
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Coffee grounds and Reishi mushroom spores can be 3D printed into a compostable alternative to plastics
Researchers have developed a new system for turning coffee grounds into a paste, which is inoculated with Reishi mushroom spores to form a mycelial skin. The skin turns the coffee grounds into a resilient, fully compostable 3D printable alternative to plastics.
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Transforming HIV diagnosis: a low-cost, point-of-care detection solution
A team of researchers has developed an innovative handheld device for human immunodeficiency virus (HIV) detection that combines paper-based sample preparation with real-time isothermal amplification.
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Ground-breaking technique deploys bacterium to deliver drugs directly to the brain
A landmark study using the nasal bacteria technique promises new treatments for neurological disorders by bypassing the blood-brain barrier.
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No more antibiotics? Scientists pioneer a safer way to protect cultured meat
A new study explores the use of Random Antimicrobial Peptide Mixtures (RPMs) as a safe and effective alternative to antibiotics in cultured meat production. These synthetic peptide cocktails eliminate bacterial contamination without harming stem cell viability or contributing to antibiotic resistance.
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Scientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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Monitoring approach could help snuff out Legionella outbreaks
Routine, relatively low-cost monitoring of several factors influencing water safety could ward off Legionnaires’ disease outbreaks in hospitals, nursing homes and other health care settings, a new study suggests.
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Researchers create world’s largest digital microbe collection to transform health research
Researchers have created the world’s largest collection of digital microbes - nearly a quarter of a million computer models - to help revolutionise our understanding of the human microbiome and its impact on health.
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A new system to study phytoplankton: Crucial species for planet Earth
Researchers have come up with a new way to study phytoplankton. They’ve built a system that can measure the light given off by individual phytoplankton cells, which tells them how efficiently each individual is using light.
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Researchers engineer biological reaction crucibles to rapidly produce proteins
Biomedical engineers have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.
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Scientists recode the genome for programmable synthetic proteins
Synthetic biologists were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform that they developed enabling the production of new classes of synthetic proteins.