All Infectious Disease articles – Page 26
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Mutating hepatitis viruses make drug treatment more difficult
Sofosbuvir and Ribavirin combination therapy efficiently decreased viral RNA in blood and stool in patients with chronic HEV infection, but variants that are associated with antiviral resistance emerged during treatment.
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Phages help to identify people at risk of developing TB
A novel approach to studying the progression of tuberculosis (TB) from infection to disease has identified and treated people at increased risk of developing the disease that current methods of testing would not.
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Molecular switch plays central role in bacterial dysentery
The regulation of virulence genes in Shigella bacteria is mediated by a CTP-dependent transcription factor.
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Spread of diarrheal illness linked to climate change
Temperature, day length and humidity have been found to be linked to the increased spread of a diarrhoeal illness a new study reveals.
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NYC virus database may advance research into factors contributing to respiratory illness severity
A study reveals how longitudinal cohort data was used to create an interactive, publicly-available website, The Virome of Manhattan Project: Virome Data Explorer to visualize cohort characteristics, infection events, and illness severity factors.
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MIddle East foot-and-mouth disease patterns underline need for unified strategies
A comprehensive study highlights repeated incursions of foot-and-mouth virus in Israel and neighbouring areas, suggesting a pattern of transmission.
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People in prison are at very high risk of tuberculosis, even years after release
A study in Paraguay evaluates tuberculosis incidence during and after incarceration in a cohort of nearly 3,000 people.
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Research reveals why staph vaccine candidates keep failing - and how to fix the problem
Research from UC San Diego explains the clinical failure of dozens of candidate vaccines for one of the most common human infections; it also suggests a way to fix the problem.
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Study opens lid on how Candida evolves and adapts to humans
Scientists have identified hundreds of genes subject to recent, clinically-relevant selection in six species of the fungal pathogen Candida.
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Scientists deliver new insights into what helps Salmonella cause infections
Researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.
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New estimate doubles likely deaths from fungal disease globally
The annual total of deaths from fungal disease worldwide has risen to 3.75 million, double the previous estimate, according to a new study.
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Nutritional acquired immunodeficiency (N-AIDS) is the leading driver of the TB pandemic
Acknowledging N-AIDS as a key determinant and comorbidity of TB can enhance the ability to detect, prevent and eliminate TB, a new review suggests.
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Experiments in infant mice suggest new way to prevent spread of flu in people
A new study in infant mice shows that keeping virus particles from attaching to sialic acids limits more than just the entry of influenza A viral infections, but also hinders their exit (shedding) and transmission from mouse to mouse.
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Glow sticks deployed to ID emerging biothreats
Glow sticks are being used by a University of Houston researcher to identify emerging biothreats for the United States Navy.
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Pirola variant of Covid rediscovers entry pathway into lung cells
Researchers have discovered that the Pirola variant enters lung cells with high efficiency and uses the cellular enzyme TMPRSS2 for entry, thereby exhibiting parallels to variants Alpha, Beta, Gamma and Delta.
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WHO prequalifies a second malaria vaccine
WHO has added the R21/Matrix-M malaria vaccine to its list of prequalified vaccines.
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Researchers unmask an old foe’s tricks to thwart new diseases
Researchers are studying Yersinia pestis, the bacterium that causes bubonic and pneumonic plague, to better understand its ability to evade the immune system and apply that understanding to control other pathogens.
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Single-point testing could miss cases of asymptomatic malaria
Dynamic, fluctuating levels of this parasite in people without symptoms argues against single-point testing to diagnose infections, a new study suggests.
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New antibiotics make TB bacterium less pathogenic for humans
Researchers have identified new, antibiotic molecules that target Mycobacterium tuberculosis and make it less pathogenic for humans.