All Infectious Disease articles – Page 13
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Significant decline of neutralising antibodies to monkeypox virus during the first month after vaccination
New research shows that even in men who receive two doses of mpox vaccine intradermally, their level of antibodies to the virus falls to low or zero within the first few months if they have not received a previous smallpox vaccine.
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TB vaccine may enable elimination of the disease in cattle by reducing its spread
Vaccination not only reduces the severity of TB in infected cattle, but reduces its spread in dairy herds by 89%, research finds.
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More older adults being diagnosed with STIs such as gonorrhoea and syphilis
STIs in Americans aged 55 to 64 years have more than doubled over the past decade; in England the number of over 45s diagnosed with gonorrhoea and syphilis doubled between 2015 and 2019.
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New enzymatic cocktail can kill tuberculosis-causing mycobacteria
A new study shows that an enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.
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Researchers a step closer to a cure for HIV
A new study demonstrates that a patented therapeutic candidate, an HIV-virus-like-particle (HLP), is 100 times more effective than other candidate HIV cure therapeutics for people living with chronic HIV on combined antiretroviral therapy (cART).
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New tech for tracking livestock disease threats
A cutting-edge computer tool that enables the mapping and tracking of the avian influenza virus across time and space will allow decision-makers to better understand infectious disease threats associated with global food systems.
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Online dashboard to help fight to save children from deadly diarrheal diseases
Researchers are developing a flexible online tool for navigating information used in the fight to save children from deadly diarrheal diseases by identifying transmission hotspots and accelerating the deployment of treatments and new vaccines.
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Insights from patient who cleared hepatitis C could lead to vaccine
By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.
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Breakthrough antibiotic shows promise against obstinate mycobacterial infections
Researchers assemble a new antibiotic candidate, COE-PNH2, offering a more effective therapeutic option against hard-to-treat mycobacterial lung diseases.
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Researchers uncover key biomolecule involved in whooping cough infection
Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough.
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Cancer therapies show promise in combating tuberculosis
A study has identified a combination of medications that may improve blood flow within granulomas, tight clusters of white blood cells formed by the body’s immune system in response to tuberculosis infection, benefiting drug delivery.
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Candida albicans toxin plays a special role in the colonization of the digestive tract
Comparative studies on mice with a complete microbiome and a microbiome reduced by antibiotics now show that the previous assumption that the yeast form of Candida albicans is better suited for colonization needs to be revised.
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New vaccine against a highly fatal tropical disease – and potential bioterror weapon – demonstrates efficacy in animal studies
In a mouse study, researchers tested a vaccine against the bacterium that causes melioidosis and found it was highly protective against the disease, which is endemic in many tropical areas.
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Scientists close in on TB blood test which could detect millions of silent spreaders
Scientists have taken a major step towards developing a blood test that could identify millions of people who spread tuberculosis unknowingly.
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New classification of tuberculosis supports efforts to eliminate the disease
A new way to classify tuberculosis (TB) that aims to improve focus on the early stages of the disease has been presented by an international team.
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Researchers ask if active screening for tuberculosis among vulnerable populations is cost-effective
Scientists present the findings of their systematic review on active pulmonary TB screening programmes run between 2008 and 2023 in so-called high-risk groups living in low TB incidence countries.
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For each 10% increase of certain bacteria type in the gut microbiome, the risk of hospitalisation for infections falls by up to a quarter
A study of two large European patient cohorts has found that for every 10% increase in butyrate-producing bacteria in a patient’s gut, the risk of hospitalisation for any infection falls by between 14 and 25% across two large national cohorts. The
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Researchers invent artificial intelligence model to design new superbug-fighting antibiotics
Researchers have invented a new generative artificial intelligence model which can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory.
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New blood test cuts infection diagnosis time from months to hours
Researchers have designed a platform to perform blood-based diagnoses of nontuberculosis mycobacteria, simplifying and shortening a long-complicated procedure from 6 months to 2 hours.
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Study maps main genes involved in immune response to infection by dengue virus
Researchers compared data for the immune response induced by natural infection and vaccines. They identified the key factors in the development of long-lasting immunity.