All Infectious Disease articles
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Papers outline 4 advances for inactivating infectious viruses and bacteria
Four papers provide insights into novel antiviral compounds and methods to inactivate infectious viral particles and bacteria.
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Study finds three new safe, effective ways to treat drug-resistant tuberculosis
An international clinical trial has found three new safe and effective drug regimens for tuberculosis that is resistant to rifampin, the most effective of the first-line antibiotics used to treat TB.
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Most Americans favor school vaccination requirements, but support is rising for opt-out options
A new survey finds that nearly three-quarters of U.S. adults support requiring that children be vaccinated against preventable diseases such as measles, mumps, and rubella.
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CARB-X funds Rhode Island Hospital to assess feasibility of direct from blood detection of bacterial pneumonia
Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award Rhode Island Hospital at Brown University Health US$1M to demonstrate proof-of-concept of a polymerase chain reaction (PCR) approach informed by RNA sequencing to detect bacterial pneumonia directly from whole blood.
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International disease classification codes ambiguities create challenges in comparing respiratory infection diagnose
The International Classification of Diseases (ICD) system standardizes diagnostic codes globally, enabling accurate comparisons of health data. This study investigated regional differences in respiratory infection diagnoses to identify potential ambiguities in ICD coding and their implications for data comparability.
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Tailored guidelines and reduced stigma needed to tackle leprosy, Irish case study reveals
A case report on an adult with an imported case of leprosy in Ireland shows that there are notable challenges in tackling the disease in settings where it is rare. The affected individual was one of five individuals with leprosy reported in Ireland in the past decade.
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V-161: A breakthrough in the fight against antibiotic-resistant VRE infections
Researchers from Japan have identified V-161, a compound that inhibits Enterococcus hirae V-ATPase activity, disrupting Na+ transport and effectively inhibiting VRE growth.
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New study finds social programs could reduce the spread of HIV by 29%
Researchers have found that addressing barriers to HIV care from depression, homelessness, individual and neighborhood poverty, education disparities, lack of insurance and unemployment could reduce the national HIV incidence by 29% over 10 years.
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Scientists culture previously uncultivable human rhinovirus C with innovative respiratory organoids
Scientists have successfully utilised human respiratory organoids (mini-organs) established by their team to propagate human rhinovirus C (HRV-C), which had previously been refractory to conventional virus cultivation.
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Towards improved pandemic preparedness: Launch of new EU project COMBINE
A project for the targeted development of antiviral therapies for newly emerging viruses, COMBINE focuses on the critical virus-cell binding step, aiming to identify key factors and potential therapeutic targets involved early in viral infections.
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Dihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
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Human papillomavirus infection kinetics revealed in new longitudinal study
Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a new study.
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WHO calls on Trump to reconsider order that USA will withdraw from the Organization
The World Health Organization has said it regrets President Donald Trump’s announcement that the United States of America intends to withdraw from the Organization.
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Extreme rain heightens E. coli risks for communities of color in Texas
New research shows that communities of color in Texas face pronounced risks of E. coli exposure in nearby waters following storms that dump abnormally high amounts of rain.
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Rotavirus protein NSP4 manipulates gastrointestinal disease severity
This study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells.
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Effectiveness and safety of tenofovir amibufenamide in the treatment of chronic hepatitis B: A real-world, multicenter study
A new study aimed to evaluate the real-world effectiveness and safety of tenofovir amibufenamide (TMF) in a cohort of patients with chronic hepatitis B (CHB).
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In the US Northeast, 50% of adult ticks carry Lyme disease carrying bacteria
A new study finds that 50% of adult blacklegged ticks in the US Northeast carry the bacteria that causes Lyme disease while 20% to 25% of the younger (nymph) blacklegged ticks carry the bacteria.
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Child undernutrition may be contributing to global measles outbreaks
A study of fully vaccinated children finds a link between stunted growth and weakened immunity, suggesting combatting child hunger could help prevent the disease’s spread.
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Review offers guidance to clinicians on animal-borne infections in the Canadian Arctic
A new review on zoonotic infections in the Canadian Arctic provides timely guidance to clinicians as the region experiences heightened global interest as well as climate change, which threatens the region and increases risk of disease transmission.
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Chain reaction: HIV vaccines can lead to antibodies against antibodies
Scientists have discovered that repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus—knowledge that could lead to better vaccines.