All Infection Prevention & Control articles – Page 6
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Nirmatrelvir/ritonavir antiviral combination shows potential in reducing COVID-19 hospitalizations
A systematic review aimed to summarize published evidence on the efficacy, effectiveness, and safety of nirmatrelvir/ritonavir for COVID-19. The review also intended to assess the robustness of the evidence from randomized controlled trials.
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New drug target identified for diseases associated with leukemia-causing virus
Researchers have found a new target for treating diseases associated with human T-cell leukemia virus type 1 (HTLV-1). Blocking kinases, which regulate cellular functions, leads to cell death caused by the degradation of the protein Tax.
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Researchers expose the rules behind dengue’s invasion strategies
Scientists uncover fundamental rules for how dengue virus infects its mosquito and human hosts, providing hope for identifying therapeutic approaches.
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Study sheds light on patterns of Leptospirosis infection
Part of a multi-year project, the study seeks to identify demographic, socioeconomic and environmental factors in a high transmission setting in Brazil.
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Scientists uncover the microbial connection between urinary bladder and vagina
A new study highlights the association between urinary and vaginal pathogenic Escherichia coli in recurrent cystitis in postmenopausal women.
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Scientists investigate effectiveness of non-pharmaceutical interventions against pathogens
Scientists have investigated the success of non-pharmaceutical interventions, analysing almost two million SARS-CoV-2 genomes that occurred in the German population during the years of the pandemic.
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Wastewater could yield thousands of novel viruses, study reveals
Deep metagenomic sequencing of wastewater in Berlin over 17 months shows this technique could help forecast disease outbreaks and monitor the spread of human pathogens. It can also reveal thousands of novel viruses, a new study reveals.
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Urgent action needed to combat rising antimalarial resistance in Africa
Urgent action is needed to prevent a surge in malaria-related sickness and death in eastern Africa, scientists say.
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Llama nanobodies deliver breakthrough in building HIV immunity
Scientists have developed a new antibody therapy that can neutralize a wide variety of HIV-1 strains. They found success in an unlikely source — llamas.
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Advanced nanofibrous membranes: tackling diabetic wounds with precision
Researchers have developed a poly (L-lactic acid) (PLLA) nanofibrous membrane enhanced with curcumin and silver nanoparticles (AgNPs), aimed at improving the healing of diabetic wounds.
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‘Treat all’ strategy for patients with chronic hepatitis B virus infection
A new review explores the implications of a ’Treat-all’ strategy for chronic hepatitis B management following the 2022 Chinese guidelines which expanded treatment indications and simplified algorithms to enhance disease management.
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Engineered nanovesicles from activated neutrophils show promise in treating infected wounds
A recent study has developed nanovesicles (NVs) from activated neutrophils, showcasing their ability to perform molecular debridement and accelerate healing in infectious wounds.
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Small animals acquire genes from bacteria that can produce antibiotics
A group of small, freshwater animals protect themselves from infections using antibiotic recipes “stolen” from bacteria, according to new research.
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The geometry of life: Physicists determine what controls biofilm growth
The fitness of a biofilm is largely impacted by the contact angle that the biofilm’s edge makes with the substrate - and this geometry has a bigger influence on fitness than anything else, including the rate at which the cells can reproduce.
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E. coli variant may cause antimicrobial resistance in dogs and humans
Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
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Kenyan crop contamination outbreak inspires grad student to improve rice storage
A new study shows that proper rice storage conditions to reduce aflatoxin risk after harvest include a temperature below 20 degrees Celsius, or 68 degrees Fahrenheit, and relative humidity below 75 per cent.
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Most Salmonella illnesses from chicken caused by few products with high levels of virulent strains
A new study shows that few products with high levels of very virulent Salmonella strains are responsible for most of the illnesses from raw chicken parts, suggesting regulation efforts should focus on detecting and preventing high-risk contamination.
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Advanced imaging reveals how a parasitic ‘kiss’ alters cell metabolism
Researchers have described how Toxoplasma infection changes host cell metabolism over the course of infection using the power of optical metabolic imaging (OMI) for the first time.
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Respiratory bacteria ‘turns off’ immune system to survive
Researchers have identified how a common bacterium is able to manipulate the human immune system during respiratory infections and cause persistent illness.
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NIH funds consortium to accelerate development of new TB treatments
A new consortium has been awarded a five-year, $31 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis.