All Infection Prevention & Control articles – Page 4
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NewsResearch team with the latest Nobel Prize laureate reveals regulatory immune cell precursors disrupted in severe COVID-19
A research team joined by Professor Shimon Sakaguchi – the latest Nobel Laureate in Physiology or Medicine – has identified a subset of immune cells called precursor T follicular regulatory cells (preTfr) that play a critical role in preventing autoantibody production.
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NewsResearchers find key to stopping deadly infection
New research has identified a key step that enables rotavirus to infect cells. The researchers found that disabling the process in tissue culture and in mice prevented infection.
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NewsNew vaccine shows promise against typhoid and invasive salmonella in first human trial
Researchers have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella–two major causes of illness and death among children in sub-Saharan Africa.
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NewsProfessor awarded $3.9 million to fight deadly parasites that threaten children and immunocompromised adults
A multi-institutional team will develop effective drugs that are urgently needed to manage cryptosporidiosis in young children, immunocompromised adults and as a countermeasure to epidemic outbreaks.
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NewsDo imported cut flowers spread livestock viruses?
A study investigated whether Culicoides biting midges are being accidentally exported from Africa to Europe in shipments of cut flowers. Although researchers did detect small numbers of these insects near and inside greenhouses on a Kenyan flower farm, they found none in packaging or transport areas.
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NewsNew study reveals where HIV hides in different parts of the body
A new study reveals that HIV cloaks itself in the DNA of infected cells using unique DNA patterns in the brain, blood and parts of the digestive tract. For example, in the brain, the virus avoids genes and hides in less active parts of the DNA.
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NewsAntibody discovered that blocks almost all known HIV variants in neutralization assays
An international research team has discovered an antibody that could advance the fight against HIV. The newly identified antibody 04_A06 proved to be particularly effective in laboratory tests. It was able to neutralize 98.5 percent of more than 300 different HIV strains, making it one of the broadest antibodies against HIV identified.
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NewsResearch reveals fetuses exposed to Zika virus have long-term immune challenges
Researchers discovered that when a pregnant mother is infected with Zika virus, the resulting inflammatory response in the placenta permanently changes how the offspring’s immune system develops - even if the infection is mild or asymptomatic in the mother.
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NewsLong Ebola: Sudan virus can persist in survivors for months, study shows
More than half of survivors of the Sudan Ebola virus still suffer serious health problems two years post-infection and the virus can persist in semen and breast milk for months after recovery, according to the first study examining the virus’s long-term effects.
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NewsScientists explore how viruses replicate and infect
Herpes viruses cultivated using one kind of host cell – known as a producer cell – exhibited differences from the same virus cultivated with a different producer cell.
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NewsResearchers deconstruct chikungunya outbreaks to improve prediction and vaccine development
Researchers analyzed more than 80 outbreaks of chikungunya virus to improve prediction of future outbreaks and inform vaccine trial development.
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NewsThe RESTART trial: a drug to block a toxic HIV molecule
What if the presence of a well-known but misunderstood viral protein explains why some people living with HIV (PLWH) never recover their health, even with antiretroviral treatment? Researchers will explore this in a groundbreaking clinical trial this fall.
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NewsSome human GII.4 norovirus are better than others at infecting cells; researchers have found out why
A study reveals that human GII.4 noroviruses have evolved a uniquely potent entry mechanism with clear strain-specific differences. The findings open new possibilities for identifying the elusive human norovirus receptor as well as developing vaccines and treatments.
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NewsBreakthrough results from elephant herpesvirus trial find vaccine to be safe
The world’s first vaccine trial against elephant endotheliotropic herpesvirus (EEHV) – a leading cause of death in young Asian elephants – is safe and triggers a strong virus-fighting immune response, according to a research team.
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NewsNew antibiotic targets IBD — and AI predicted how it would work before scientists could prove it
The new antibiotic, enterololin, attacks and kills only a specific group of disease-causing bugs, which includes the type of E. coli that drives Crohn’s disease. It is a promising new treatment option for people affected by Crohn’s and other IBD-related conditions.
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NewsGenetic ‘Trojan horse’ selectively kills cancer cells linked to Kaposi’s sarcoma
A highly targeted gene therapy that could revolutionize treatment for cancers linked to a common herpesvirus harnesses an adeno-associated virus (AAV) to deliver a genetic “Trojan horse” into infected cells.
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NewsQdenga vaccine shows effectiveness against dengue under real-world conditions during Brazil’s 2024 outbreak
An international team of researchers has demonstrated that the tetravalent dengue vaccine Qdenga provides significant protection against the disease under real-world conditions, during the large 2024 epidemic in São Paulo, Brazil.
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NewsGene editing, traditional crossbreeding produce disease-resistant cacao plants
Researchers reported that they edited the gene TcNPR3 in cacao plants, ultimately resulting in disease-resistant cacao plants that had 42% smaller disease lesions when infected with phytophthora, compared to non-edited plants.
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NewsNew insights into how pathogens build protein machinery for survival in the gut
New research reveals how pathogenic bacteria construct tiny protein-based compartments, known as Eut microcompartments, which enable them to digest ethanolamine - a nutrient commonly found in the gut.
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NewsScientists uncover molecular mechanisms for bacterial lipid transport
Researchers have successfully applied cryo-electron microscopy (cryo-EM) to unveil the molecular structures of critical protein machines that transport lipids and maintain the outer membrane (OM) barrier of Gram-negative bacteria.