All Infection Prevention & Control articles
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New study suggests Florida has the potential for local Chagas disease transmission
Researchers in Florida have discovered local kissing bugs are harboring the parasite that can lead to Chagas disease, demonstrating that this rare, chronic disease has a secure foothold in the U.S. and warrants more preventative measures.
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Clinical trials reveal promising alternatives to high-toxicity tuberculosis drug
Research shows two novel antibiotics could spare patients from severe side effects. The drugs sutezolid and delpazolid have demonstrated strong antimicrobial activity and a notably better safety profile compared to linezolid.
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Low dose of hydroxychloroquine is associated with reduced COVID-19 mortality: study
A new study provides observational evidence that low-dose hydroxychloroquine is associated with reduced COVID-19 mortality in hospitalized patients, particularly those with severe illness, when administered within the first week of symptoms.
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Researchers develop AI tool to detect surgical site infections from patient-submitted photos
Researchers have developed an artificial intelligence (AI) system that can detect surgical site infections (SSIs) with high accuracy from patient-submitted postoperative wound photos, potentially transforming how postoperative care is delivered.
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New breakthrough uncovers how to kill ‘zombie’ TB cells resistant to antibiotics
Researchers exposed a library of over 500,000 genetically modified tuberculosis bacteria to two commonly used antibiotics. By analysing the survivors, they pinpointed genes whose disruption significantly reduced the number of surviving persisters.
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Scientists find flawed data in recent study relevant to coronavirus antiviral development
A new study shows why scientists still don’t know how the NiRAN domain works. The findings could have sweeping implications for drug developers already working to design antivirals based on flawed assumptions, and underscore the importance of rigorous validation.
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T cells take aim at Chikungunya virus
A new study offers the first-ever map of which parts of Chikungunya virus trigger the strongest response from the body’s T cells, bringing researchers closer to developing Chikungunya vaccines or therapies that harness T cells to strike specific targets to halt infection.
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World’s first AI system for single-tooth prediction of early childhood caries detection with over 90% accuracy
Scientists have developed the world’s first artificial intelligence (AI) system capable of predicting early childhood caries risk for individual teeth based on microbial characteristics, achieving an accuracy rate of over 90%.
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Study reveals engineered bacterial vesicles to combat antimicrobial resistance
Researchers studying extracellular vesicles (EVs)-membrane-bound nanoparticles released by cells that transport biologically active molecules like proteins or nucleic acids have engineered EVs derived from lactic acid bacteria to carry pathogen-specific endolysins on their surface.
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Vaccination support program reduces pneumonia-related mortality by 25 per cent among the elderly
Findings based on efforts in Sera Town, Japan showed the pneumococcal vaccination support program reversed the previously increasing trend in pneumonia mortality rate in the community.
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The gut’s secret weapon: viruses that heal
A comprehensive new review reveals how gut viruses interact with gut bacteria and host immunity, highlighting their roles in conditions like inflammatory bowel disease, colorectal cancer, and C. difficile infection. The findings offer a compelling case for harnessing the virome in novel therapies to reshape gut ecology and restore health.
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Study yields new insights into infection strategy of Pseudomonas aeruginosa
Scientists have uncovered a previously unknown trick used by Pseudomonas aeruginosa - the bacterium can functionally organize itself in diverse ways within a population of identical clones, as if it were not just one germ, but many at once. A mechanism of epigenetic memory preserves the activity of certain genes across generations.
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Scientists target ‘molecular machine’ in the war against antimicrobial resistance
The ‘molecular machine’ flagellum is essential for bacteria to cause infection, allowing bacteria to ‘swim’ around the bloodstream until finding something to infect. But it could also be a target for antibiotics.
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Novel flu vaccine adjuvant improves protection against influenza viruses, study finds
Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant that enhances the body’s immune response, according to a study.
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Research suppresses coronavirus by targeting Mac1
A new study details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the “macrodomain,” found in all coronaviruses such as SARS-CoV-2 and MERS-CoV.
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New ECDC weekly reports and guidance to tackle mosquito-borne diseases across Europe
As Europe enters this year’s mosquito season, ECDC has launched a new series of weekly epidemiological surveillance updates and public health guidance on mosquito-borne diseases.
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With AI, researchers find increasing immune evasion in H5N1
A new analysis suggests that the H5N1 avian influenza virus is evolving clever strategies. Using artificial intelligence tools, researchers analyzed thousands of viral proteins and found that their bonds to protective antibodies have weakened over time.
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Study links influenza A viral infection to microbiome, brain gene expression changes
Infection with influenza A is found to be associated with disruptions in newborn piglets’ nasal and gut microbiomes and with potentially detrimental changes in gene activity in the hippocampus, a brain structure that plays a central role in learning and memory.
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Herpes virus plays interior designer with human DNA
Researchers have discovered the cold sore virus reshapes the human genome’s architecture, rearranging its shape in three-dimensional space so that HSV-1 can access host genes most useful for its ability to reproduce.
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New vaccine works against multiple fungal infections
A vaccine developed by University of Georgia researchers successfully protects against and treats vaginal yeast infections in mice, according to a study.