All Infection Prevention & Control articles
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Ultrasensitive test detects, serially monitors intact virus levels in patients with COVID-19
A highly sensitive approach, adapted from cancer vesicles detection, was discovered to be able to detect SARS-CoV-2 viral particles in fluid samples of patients with acute COVID-19 infections.
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Antiviral protein causes genetic changes implicated in Huntington’s disease progression
A new study shows APOBEC enzymes, which normally help fight viral infections by mutating viral DNA, are unusually active in the brains of Huntington’s patients.
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Underestimated risk: Germs in the kitchen
In the most recent BfR consumer monitor, only 17 per cent of respondents said they were concerned about kitchen hygiene. The level of concern about microplastics (68 per cent) and residues of plant protection products in food (52 per cent) is significantly higher.
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New paper creates roadmap for the next generation of bioelectronic medicine
A new paper offers a roadmap to the future of bioelectronic medicine — which makes use of electrical signals instead of drugs to diagnose and treat disease.
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Towards improved pandemic preparedness: Launch of new EU project COMBINE
A project for the targeted development of antiviral therapies for newly emerging viruses, COMBINE focuses on the critical virus-cell binding step, aiming to identify key factors and potential therapeutic targets involved early in viral infections.
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Dihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
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A Marburg virus outbreak was confirmed in Tanzania
WHO has announced that an outbreak of Marburg virus disease in Tanzania has been confirmed, with 25 suspected cases. Outbreak control measures have been established since the announcement.
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Sophisticated early warning system: How bacteria respond to threats
Recent research has found that exogenous petidoglycan fragments of Vibrio cholerae and other multidrug-resistant pathogens are able to trigger 3D biofilm formation as an universial danger response.
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Bacteria in polymers form cables that grow into living gels
Scientists have discovered that bacterial cells growing in a solution of polymers, such as mucus, form long cables that buckle and twist on each other, building a kind of “living Jell-O.”
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Extreme rain heightens E. coli risks for communities of color in Texas
New research shows that communities of color in Texas face pronounced risks of E. coli exposure in nearby waters following storms that dump abnormally high amounts of rain.
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Rotavirus protein NSP4 manipulates gastrointestinal disease severity
This study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells.
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Effectiveness and safety of tenofovir amibufenamide in the treatment of chronic hepatitis B: A real-world, multicenter study
A new study aimed to evaluate the real-world effectiveness and safety of tenofovir amibufenamide (TMF) in a cohort of patients with chronic hepatitis B (CHB).
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In the US Northeast, 50% of adult ticks carry Lyme disease carrying bacteria
A new study finds that 50% of adult blacklegged ticks in the US Northeast carry the bacteria that causes Lyme disease while 20% to 25% of the younger (nymph) blacklegged ticks carry the bacteria.
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The hunt narrows for Ebola virus hosts
A cholesterol-trafficking receptor, Niemann-Pick C1 (NPC1), was identified for more efficient surveillance of host reservoirs of filoviruses, including Ebolaviruses. It narrows down the host species of the virus and links to the geographic information of pathogen emergence.
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Changes in microbiome predict risk for sexually transmitted disease
Researchers have found that bacterial vaginosis consists of two subtypes—one of which significantly increases the risk of developing chlamydia infections.
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Study identifies ventilation strategies to prevent super-spreader events aboard cruise ships
New research emphasises the importance of targeted ventilation strategies to reduce disease transmission risk on cruise ships, with crowded dining spaces identified as priority areas for improved air circulation.
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Bird flu is mutating - but antivirals still work
Researchers have identified nine mutations in a bird flu strain from a person in Texas. The bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective.
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CARB-X funds Melio to develop rapid diagnostic to detect neonatal sepsis
CARB-X will award biotechnology company Melio US$3.5M to develop and execute a technical feasibility workplan for its culture-free platform designed to identify blood stream infections including neonatal sepsis.
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Promising COVID-19 vaccine development in animal trials
Researchers developed a COVID-19 vaccine that deploys virus-like particles (VLPs) for immunity stimulation in mice.
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Pet dogs often overlooked as spreader of antimicrobial-resistant Salmonella
Household dogs are an overlooked transmission point for zoonotic pathogens such as nontyphoidal Salmonella, which can cause diarrhea, fever and abdominal cramps, with some infections potentially having life-threatening complications.