All Immunology articles – Page 5
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Respiratory bacteria ‘turns off’ immune system to survive
Researchers have identified how a common bacterium is able to manipulate the human immune system during respiratory infections and cause persistent illness.
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Hepatitis C leaves ‘scars’ in immune cells even after successful treatment
Researchers have discovered that traces of ‘epigenetic scars’ remain in regulatory T cells and exhibit sustained inflammatory properties long after the Hepatitis C virus is cleared from the body.
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Scientists discover how to improve vaccine responses to potentially deadly bacterium
Researchers have shown in an animal model that targeting a key suppressive immune molecule (IL-10) during the delivery of a vaccine improves the ability of the vaccine to protect against infection.
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Study backs RSV vaccine safety during pregnancy
Vaccinating mothers against respiratory syncytial virus (RSV) during late pregnancy to protect their newborns is not associated with an increased risk of preterm birth or other poor outcomes, according to a new study.
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Uncovering ‘Blockbuster T cells’ in the gut wins major prize
Kazuki Nagashima developed a method with which to zero in on individual gut bacterium’s impacts on T cells. His work showed that – contrary to what has been thought – some T cells in the gut can interact with multiple bacteria.
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Researchers reveals why recombinant BCG induces a stronger and longer-lasting response
Researchers are working on a more potent version of the BCG vaccine that protects against TB. While the conventional immunizer reduced infection by 90% in experiments with mice, the recombinant BCG increased protection rates to 99%.
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From ‘hit to vial’: Discovery and optimization of a promising vaccine adjuvant
Scientists identified a new and promising adjuvant, dubbed PVP-037 - in principle, this compound can be added to any vaccine to enhance its action.
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Cancer drug could be repurposed to fight Covid-19
Twelve years ago, cancer researchers identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue. In new research, they show that the same molecule does the same thing in lung tissue infected with COVID-19.
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Scientists unravel life-saving effect of dexamethasone in COVID-19
Researchers have discovered how the cortisone compound dexamethasone influences the impaired inflammatory response to Covid-19 and which patients benefit from it.
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Revealed: new factor associated with the risk of severe COVID-19 in people with obesity
By analyzing samples from obese non-diabetics, researchers found that high blood levels of saturated fatty acids cause pre-activation of innate immune cells that, when infected with SARS-CoV-2, produce elevated levels of inflammatory molecules.
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Common respiratory infections may have protected children from COVID-19, study suggests
Analyzing nasal swabs taken during the pandemic, researchers suggest that the frequent presence of other viruses and bacteria may have helped to protect children from the worst effects of COVID-19 by boosting their immune systems.
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Researchers harness intratumoral microbiome against colorectal cancer
Scientists have established a microbiota-targeted drug delivery system that exhibits high efficiency in colorectal cancer targeting and colon retention.
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Features
Infection, immunity and the One Health response in Indonesia
Infectious diseases (IDs) are a major health issue in Indonesia, as in many tropical low- and middle-income countries (LMICs), placing a significant economic burden on limited resources. Vaccination may have a critical role to play in the prevention of zoonotic infectious diseases.
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Imaging measles fusion process reveals pathway to powerful weapon
Scientists have harnessed an imaging technique called cryo-electron microscopy to show—in unprecedented detail—how a powerful antibody can neutralize the measles virus before it completes the process of fusing into the host cell membrane.
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Researchers describe a new hybrid antibody that fights streptococcus and Covid-19
Scientists who developed antibodies targeting both SARS-CoV-2 and streptococcal bacteria, from patients infected with these diseases, have described a new hybrid antibody created by combining parts from two IgG subgroups.
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Edited BCG offers potential vaccine to prevent tuberculosis in people of all ages
TB remains the leading cause of death by infectious disease globally, with South Africa having one of the highest incidence rates in the world. Source: Y tambe Apparatus for BCG vaccination - Kuchiki’s needle While the BCG vaccine used to prevent TB is widely available for infants, ...
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Researchers advise strengthening immunity against COVID-19 in people with cancer
Researchers who led a study on the effectiveness of vaccines against COVID-19 among cancer patients in Catalonia, have recommended administering additional doses of the vaccine among this risk population.
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Recombinant protein offers potential as TB booster vaccine
No new vaccine has yet surpassed BCG, which is a highly effective live vaccine and is very effective in preventing tuberculosis in children. Creating a booster vaccine to strengthen immunity in adults is considered a promising and realistic option.
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Sepsis patients could get the right treatment faster, based on their genes
New research uncovers how different people respond to sepsis based on their genetic makeup, which could help identify who would benefit from certain treatments and lead to the development of targeted therapies.
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Uncovering the potential of ‘golden flower’ and its fermentation application in tea
A new review examines the biological characteristics and fermentation applications of Eurotium cristatum, commonly known as the ’golden flower’, a dominant microbial strain in the fermentation process of Fu brick tea.