All Immunology articles – Page 4
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Scientists uncover key clues to how a viral infection can lead to arthritis-like disease
By studying Chikungunya virus, scientists have shed light on how immune responses to viral infections may lead to persistent symptoms of autoimmune disease.
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Survival trick: Pathogen taps iron source in immune cells
The body defends itself against pathogens by depriving them of vital iron. However, researchers have discovered that Salmonella bacteria specifically target iron-rich regions within immune cells to replicate, evading the immune defense.
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Common drugs can help viruses spread
JAK inhibitors are often prescribed for autoimmune diseases and inflammatory conditions such as rheumatoid arthritis, but scientists have found they also weaken the body’s natural defences against viruses.
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How the Epstein-Barr virus promotes its spread within the body
Researchers have discovered that the Epstein-Barr virus (EBV) increases the ability of infected immune cells to migrate. In this way, the pathogen promotes its spread in the body – a discovery that may have therapeutic implications.
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Study probes why patients with mitochondrial disease are more susceptible to infections
A new study shows that damaged mitochondria put the immune system in a constant state of alert, leading to dangerous overreactions when patients with rare mitochondrial diseases encounter bacteria.
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Novel molecular maneuver helps malaria parasite dodge the immune system
Researchers have discovered how a parasite that causes malaria when transmitted through a mosquito bite can hide from the body’s immune system. Plasmodium falciparum can shut down a key set of genes, rendering itself “immunologically invisible.”
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New treatment targets link between viral infection and Alzheimer’s disease
A unique mechanism triggering Alzheimer’s disease draws attention: viral infection—while ALT001 is confirmed to alleviate neuroinflammation and suppress viral replication.
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Particles carrying multiple vaccine doses could reduce the need for follow-up shots
Researchers are working to develop microparticles that can release their payload weeks or months after being injected. This could lead to vaccines that can be given just once, with several doses that would be released at different time points.
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Two HIV vaccine trials show proof of concept for pathway to broadly neutralizing antibodies
A new study combining data from two separate phase 1 clinical trials shows that a targeted vaccine strategy can successfully activate early immune responses relevant to HIV, and, in one trial, further advance them.
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Scientists find two brain biomarkers in long COVID sufferers may be what’s causing brain fog
A new study that compares inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows those with cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.
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Yellow fever vaccination: how strong immune responses are triggered
Researchers have shown how specific immune cells are activated by the vaccine – an important starting point for the development of new vaccines.
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Scientist awarded $500,000 Gruber Genetics Prize for pioneering discoveries in bacterial immune systems
The 2025 Gruber Genetics Prize is being awarded to geneticist and molecular biologist Rotem Sorek, Ph.D., of the Weizmann Institute of Science, for his discoveries in the immune system of bacteria.
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Researchers reveal lipid-based communication between body and gut microbes
A new study shows how a host protein can specifically recognize bacterial lipids, thus triggering beneficial immune responses. It also highlights a new way the body actively shapes the gut microbiome by communicating with microbes to maintain balance.
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‘Loop’hole: HIV-1 hijacks human immune cells using circular RNAs
In a groundbreaking discovery, researchers have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body’s natural defenses and use it to support its survival and replication.
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Scientists reveal key bacterial immune mechanism
Researchers have uncovered a pivotal mechanism by which bacteria defend themselves against viral infection. Cyclic dinucleotides (CDNs), synthesized during activation of the cyclic oligonucleotide-based anti-phage signaling system (CBASS) immune mechanism, trigger the filamentous assembly of phospholipase effectors, which execute the downstream immune response.
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New study offers insights into designing safe, effective nasal vaccines
Researchers found that nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, even without the help of immune-boosting ingredients known as adjuvants. The findings, researchers suggest, may offer critical insights into developing safer, more effective nasal vaccines in the future.
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New discovery explains why men are more affected by severe COVID-19
Researchers have found another piece of the puzzle that explains why there are differences in immune responses in women and men when they get sick with COVID-19. This discovery has implications for treatment strategies for severe COVID-19.
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New vaccine protects against swine, human and bird flu
Annual flu shots could become a thing of the past under a new vaccine strategy. A new study describes a vaccine that protects against H1N1 swine flu and can also protect against influenza in humans and birds.
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COVID-19 caused by the Omicron variant in lung transplant recipients: a single center case series
A new study investigates the risk factors for developing severe disease in lung transplant patients as a result of the Omicron variant of Covid-19.
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Heart rhythm disorder traced to bacterium lurking in our gums
A new study finds that a gum disease bacterium can slip into the bloodstream and infiltrate the heart. There, it drives scar tissue buildup—known as fibrosis—distorting the heart’s architecture, interfering with electrical signals, and raising the risk of atrial fibrillation (AFib).