All Immunology articles – Page 4
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Men infected with high-risk types of HPV could struggle with fertility
Men infected with high-risk HPV genotypes show evidence of sperm death from oxidative stress and an impaired immune response, a new study suggests.
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Next time you beat a virus, thank your microbial ancestors
When you get infected with a virus, some of the first weapons your body deploys to fight it were passed down to us from our microbial ancestors. Two key elements of our innate immune system came from a group of microbes called Asgard archaea.
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Scientists to investigate why men and women are hit by the flu differently
Turns out that there is a biological reason why women and men suffer viral infections like influenza differently – and a team of scientists are extending their research to better understand why and how to design better, possible sex-specific treatments.
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New vaccine against cervical cancer combines prophylactic and therapeutic activity
Scientists at the German Cancer Research Center (DKFZ) have developed a completely new vaccination concept with a new vaccine against cancer-causing human papillomaviruses (HPV).
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New evidence for a connection between antibiotic use and autoimmune diseases
A new connection has been revealed between depletion of gut bacteria caused by antibiotics and development of autoimmune diseases. Clearance of dead cells involves not only local signals from within a tissue but also distant signals from other parts of the body.
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Nanoparticle platform offers step toward more effective Covid and HIV vaccines
Researchers have developed a nanoparticle platform that could make existing vaccines more effective, including those for influenza, COVID-19, and HIV.
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New technique offers insights into the complexities of chronic Hepatitis B infection
A new technique called spatial transcriptomics is used to gain a deeper understanding of the interplay between chronic hepatitis B (CHB) infection and the immune system within the liver, paving the way for developing novel therapeutic strategies.
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Dengue vaccine is effective and safe, reveals first global meta-analysis
The study, conducted by cross-referencing data from 19 scientific studies, involving over 20,000 individuals, shows an efficacy rate of over 50% in reducing disease cases, with lasting effects and a high safety profile.
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New two-step flu vaccine strategy shows promise in pig model
A new, two-step flu vaccination strategy that pairs intramuscular injection of a viral vectored flu vaccine with nasal spray administration of a novel attenuated live flu virus appears to be safe and effective in pigs.
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Do smells prime our gut to fight off infection?
A recent study shows that the nematode C. elegans reacts to the odor of pathogenic bacteria by preparing its intestinal cells to withstand a potential onslaught.
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Scientists get to the bottom of COVID’s worst pediatric complication
Scientists investigating multisystem inflammatory syndrome in children (MIS-C) found their immune systems had latched onto a part of the coronavirus that closely resembles a protein found in their bodies, launching an attack on their own tissues.
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Study explains why virus causing cold sores does not spread to devastating brain infection
Researchers have discovered a previously unknown defence mechanism in the body that is the reason why herpes infection causes a serious and potentially fatal brain inflammation in only one out of 250,000 cases.
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Researchers make breakthrough in bid to develop vaccines and drugs for neglected tropical disease
Scientists have developed a new, safe and effective way to infect volunteers with the parasite that causes leishmaniasis and measure the body’s immune response, bringing a vaccine for the neglected tropical disease a step closer.
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Mouse study reveals how fetal brain impacted when mother fights severe flu
A bad case of the flu during pregnancy can increase the risk for fetal neurodevelopmental disorders such as schizophrenia and autism spectrum disorder. But it’s not the virus itself doing the damage; it’s the mother’s immune response.
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Scientists uncover genes that contribute to severe COVID-19 susceptibility
Researchers confirmed the central and already known role of the TLR7 gene in severe courses of the disease in men, but were also able to find evidence for a contribution of the gene in women.
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Prenatal Zika infection has long-term immune consequences in children, even without microcephaly
New findings challenge the current diagnostic criteria for congenital Zika syndrome, expanding the definition beyond skull or brain abnormalities.
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Study identifies unpredicted immune responses to adenoviral COVID vaccines
Researchers have identified unpredicted T-cell immune responses to the adenoviral (Oxford/AstraZeneca and Janssen) COVID-19 vaccines, but not to the mRNA vaccines.
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Study shows promise for a universal influenza vaccine
New research reveals a promising approach to developing a universal influenza vaccine — a so-called “one and done” vaccine that confers lifetime immunity against an evolving virus.
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Study identifies protein that helps COVID-19 virus evade immune system
Discovery of a new viral evasion mechanism, and of a monoclonal antibody that subverts it, is an advance in immunotherapy that offers the prospect of effective host-directed treatment to combat infections.
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Early life antibiotic increases risk of asthma: providing clues to a potential prevention adult asthma
Early exposure to antibiotics can trigger long term susceptibility to asthma, according to researchers who isolated a molecule produced by gut bacteria that in the future could potentially be trialed as a dietary supplement for children at risk of asthma.