All Immunology articles – Page 4
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NewsSingle-cell insights reveal how HPV status reshapes penile tumor immunity
A study found that HPV-positive tumors in penile squamous cell carcinoma cases contained fewer proliferative macrophages and less exhausted CD8+ T cells, along with stronger chemokine signaling, revealing distinct immune remodeling associated with HPV infection.
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NewsNo-needle test can tell if flu/COVID vaccines are effective
A team of researchers has developed a skin patch that can detect antibodies associated with COVID and flu infections. It’s orders of magnitude more sensitive than existing tests, uses just a half volt of electricity, and can return results in 10 minutes.
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NewsGut microbiota: implications in pathogenesis and potential therapeutic target in primary biliary cholangitis
A new review synthesizes current evidence on gut microbiota dysbiosis in PBC, elucidates its pathogenic mechanisms, and explores its potential as both a diagnostic biomarker and a novel therapeutic target.
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NewsHidden HPV-linked cell type may drive early cervical cancer, scientists report
A new study identifies tumor-promoting keratinocytes linked to HPV infection and poor prognosis. Scientists employed single-cell RNA sequencing (scRNA-seq) and multiplex immunohistochemistry (mIHC) to delineate the molecular landscape of early-stage CESC.
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NewsCOVID-19 vaccination lowers long COVID risk in adolescents
Adolescents who were vaccinated against COVID-19 were less likely to develop long COVID after their first SARS-CoV-2 infection than unvaccinated peers, finds a new study.
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NewsNew nasal vaccine has potential to transform respiratory disease prevention
Researchers have demonstrated that their nasally-delivered, antibiotic-inactivated Bordetella pertussis (AIBP) vaccine not only prevents severe disease but also curbs bacterial transmission — an achievement long sought by vaccine developers worldwide.
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NewsERC Synergy Grant awarded to physicist Michael Lässig and virologist Florian Klein
Researchers have been awarded a Synergy Grant by the European Research Council (ERC) for the project CoEvolve, which investigates the co-evolution of viruses and the immune system.
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NewsTemporary benefit for immune system in early HIV treatment, but dysregulation returns
A study investigated whether immune dysregulation can be prevented by starting HIV medication immediately after infection. Six months after this early treatment, the immune system did indeed work as in people without HIV, but in the longer term, the immune system was disrupted again.
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NewsNew study links gut microbes to common heart disease - suggesting ‘Jekyll and Hyde’ action
Researchers studying gut microbes recently identified 15 bacterial species associated with coronary artery disease. The analysis reveals multiple pathways linked to disease severity, including increased inflammation and metabolic imbalance.
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NewsCOVID-19 vaccination linked to reduced infections in children with eczema
Children with atopic dermatitis (AD), commonly known as eczema, may experience fewer infections and allergic complications if they receive the COVID-19 vaccine, according to new research.
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NewsEarly-stage clinical trial demonstrates promise of intranasal influenza vaccine in generating broad immunity
Researchers report encouraging results from an early phase clinical trial that found an experimental intranasal vaccine triggered a broad immune response against multiple strains of H5N1 ’bird flu’, highlighting the potential of mucosal immunization strategies.
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NewsAI can speed antibody design to thwart novel viruses: study
Artificial intelligence (AI) and “protein language” models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study
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NewsNew study finds targets for a new tuberculosis vaccine
A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world’s deadliest infectious disease.
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NewsResearchers capture first high-res images of deadly yellow fever virus
Researchers have captured the first high-resolution images of the yellow fever virus (YFV), a potentially deadly viral disease transmitted by mosquitoes that affects the liver.
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NewsNew insights on gut microbes that prevent formation of cancer-causing compounds
Gut microbes metabolize dietary nitrates and nitrites and prevent the formation of cancer-causing compounds called nitrosamines. New research sheds light on these processes and pinpoints which types of bacteria are most important.
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NewsResearch finds higher rare risk of heart complications in children after COVID-19 infection than after vaccination
A whole-population study showed that although these conditions were rare, children and young people were more likely to experience heart, vascular or inflammatory problems after a COVID-19 infection than after having the vaccine — and the risks after infection lasted much longer.
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NewsNew study reveals not all bats carry equal viral risk
A groundbreaking study sheds new light on the relationship between bats and dangerous viruses, showing that contrary to widespread assumptions, not all bats carry viruses with high epidemic potential, only specific groups of species.
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NewsResearchers pinpoint target for treating virus that causes the stomach bug
Human astroviruses are a leading viral cause of the stomach bug, often leading to vicious cycles of sickness and malnutrition. New research reveals the strategy that the human astrovirus uses to enter the body.
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NewsUnderweight and unbalanced: Gut microbial diversity in underweight Japanese women
A study of underweight Japanese women reveals they showed reduced gut microbiota diversity and enrichment of taxa associated with inflammatory tendencies. The findings suggest that gut health is as important as caloric intake when it comes to addressing low body weight.
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NewsResearch spotlight: Mapping how gut neurons respond to bacteria, parasites and food allergy
A new study adds to accumulating evidence showing that the enteric nervous system works closely with the immune system to help the body respond to bacteria, parasites and allergens. The ENS also plays a key role in how the body maintains balance and protects itself from harm.