All Immunology articles – Page 3
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NewsEpigenetic rewiring fuels potato susceptibility to late blight
Scientists performed whole-genome bisulfite sequencing and RNA sequencing on the widely cultivated potato cultivar Qingshu No.9 following Phytophthora infestans infection, uncovering dynamic DNA methylation shifts that correlate with large-scale transcriptional reprogramming and immune suppression.
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NewsStudy reveals immune blueprint for next-generation malaria vaccine
New research has uncovered how the human immune system fights Plasmodium vivax, paving the way for the first effective vaccine against the most widespread form of malaria. It provides critical evidence of how protective immunity to P. vivax works, identifying specific targets on the parasite.
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NewsProtein interplay offers insights into how the immune system recognizes viral RNA
A new study reveals how two proteins cooperate in a key early step of antiviral detection. Using cryo-electron microscopy and high-speed atomic force microscopy, researchers found that LGP2 binds to viral RNA and recruits MDA5 molecules, as if threading beads on a string.
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NewsPeople’s gut bacteria worse in areas with higher social deprivation
Living in a poorer neighbourhood in the UK could impact the make-up of your gut microbiome, potentially leading to worse health. New research found that people living in areas of higher social deprivation have a less diverse range of bacteria in their gut.
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NewsDiffering immune responses in infants may explain increased severity of RSV over SARS-CoV-2
Reseachers report that the two respiratory viruses trigger different immune responses. Those differences might explain why these two diseases have different clinical outcomes and require different treatment strategies.
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NewsMeningococcal B vaccination does not reduce gonorrhoea, trial results show
Contrary to existing evidence from observational studies, the meningococcal B vaccine (4CMenB) has no effect on preventing the acquisition of gonorrhoea, according to the results of the world’s largest randomised control trial (RCT) into possible efficacy.
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NewsHow citrus rewires its vascular system to fight Huanglongbing
By profiling thousands of individual cells, researchers mapped how different vascular cell types in citrus roots respond during early stages of infection with Candidatus Liberibacter asiaticus, revealing profound changes in cell fate, gene expression, and tissue differentiation.
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NewsStudy reveals key differences in long-term brain effects of COVID-19 and flu
While both Covid and flu can leave lasting lung damage, only SARS-CoV-2 infection caused persistent brain inflammation and small blood vessel injury, even after the virus was no longer detectable, a new study has found.
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NewsNew strategies aim at HIV’s last strongholds
A new study has overcome a long-standing challenge—how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease difficult to cure.
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News Huayunuo approval positions China at forefront of viral hepatitis innovation, says GlobalData
Huahui Health has recently secured conditional approval from China for Huayunuo (Libevitug Injection), marking it as the first domestically developed monoclonal antibody (mAb) drug for chronic hepatitis D virus (HDV) infection in adults with or without compensated cirrhosis.
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NewsNovel camel antimicrobial peptides show promise against drug-resistant bacteria
Researchers have identified three novel antimicrobial peptides (AMPs) from dromedary camels that effectively target multidrug-resistant bacteria, offering potential alternatives to conventional drugs.
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NewsNew single-cell transcriptomic clock reveals intrinsic and systemic T cell aging in COVID-19 and HIV
Scientists developed a new single-cell transcriptomic clock called T immune cell transcriptomic clock (Tictock) to measure aging in specific immune cells. They found that in patients with acute Covid-19, the infection increased the biological age of naïve CD8 T cells.
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NewsHoly Grail: One vaccine may provide broad protection against many respiratory infections and allergens
In a new study in mice, researchers have developed a universal vaccine formula that protects against a wide range of respiratory viruses, bacteria and even allergens.
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NewsNew findings on infection with the Epstein-Barr virus
Researchers have identified genetic and non-genetic factors that help the body fight the Epstein-Barr virus. Using a new technique, they were able to estimate the amount of EBV in the blood and find correlations in large health data sets – for example, an increased viral load in people with HIV infections, but also in smokers.
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NewsMissed opportunity: Study shows low vaccination rates among expectant mothers in Norway against COVID-19 and influenza
A study of over 50,000 pregnant women in Norway during the 2023/24 influenza season found that only 29.9% were vaccinated against influenza and 12.1% against COVID-19 during pregnancy, remaining far below recommended targets.
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NewsResearchers discover how tuberculosis bacteria use a “stealth” mechanism to evade the immune system
New research reveals that mycobacteria release tiny packages called extracellular vesicles that fuse with the membranes of immune cells. These vesicles contain specialized lipids—fatty molecules—that make the cell membrane more rigid.
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NewsPrenatal infection increases risk of heavy drinking later in life
Exposure to infection and other immune stress in the womb increases the likelihood of alcohol misuse in adulthood, a risk that may be reduced through prenatal antioxidant treatment, a new study shows.
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NewsNovel vaccine protects against C. diff disease and recurrence
A novel vaccination approach cleared the harmful gut bacterium Clostridioides difficile in an animal model of infection. An experimental vaccine administered to the mucosal lining of the colon protected against illness, death, tissue damage and infection recurrence.
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NewsGlobal scientific paper establishes first consensus definition of gut health
A global group of 13 scientists and clinicians is helping establish clarity by publishing a consensus definition of gut health. They define gut health as “a state of normal gastrointestinal function without active gastrointestinal disease and gut-related symptoms that affect quality of life.”
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NewsMacrophage immune cells need constant reminders to retain memories of prior infections
Researchers have discovered that immune cells known as macrophages remain poised to fight repeat infections due to the persistent presence of signaling molecules left behind during previous infections.