All Immunology articles – Page 2
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NewsPrevalence of neutralizing antibodies to AAV2 and AAV9 in individuals with Niemann-Pick disease
A new study shows that more than half of individuals with Niemann-Pick disease, type C1 (NPC1) who were tested lacked neutralizing antibodies against either adeno-associated virus (AAV) 2 or AAV9.
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NewsInhaled COVID vaccine study begins recruitment for phase-2 human trials
Researchers have started a phase-2 clinical trial on a next-generation, inhaled COVID-19 vaccine. Findings from the phase-1 trial indicate that the vaccine is more effective at inducing immune responses than traditional injected vaccines are.
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NewsGenes combined with immune response to Epstein-Barr virus increase MS risk
In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.
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NewsNew study links sleep debt and night shifts to increased infection risk among nurses
A new study examining the effects of sleep patterns and shift work on the immune system has found that sleep debt and night shifts increase the risk of several common infections in nurses.
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NewsTB vaccine candidate provides ‘elite’ protection
A tuberculosis vaccine candidate under development shows complete protection and superior immune response in nonhuman primates compared to the existing BCG vaccine.
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NewsResearch identifies key antibodies for development of broadly protective norovirus vaccine
A new study identifies powerful antibodies capable of neutralizing a wide range of norovirus strains. The finding could lead to the design of broadly effective norovirus vaccine, as well as the development of new therapeutic antibodies.
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NewsBAADesign enables the immune escaped etesevimab fully-armed against SARS-CoV-2 Omicron subvariants
BAADesign offers a powerful tool for reengineering monoclonal antibodies to combat emerging SARS-CoV-2 variants, providing a scalable solution for future pandemic preparedness, according to a new study.
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NewsScientist who deployed glowing stars to detect disease named fellow of the Royal Society of Chemistry
The man who turned the science of glow-in-the-dark stars into ways to detect disease, Professor Richard Willson, has been elected as a fellow of the Royal Society of Chemistry.
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NewsWhite blood cells use brute force to dislodge bacteria
A $2.3 million grant from the National Institutes of Health (NIH).will support research into blood platelets and macrophages; how integrin tension influences cell function; and how this force affects platelet behavior.
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NewsCentauri Therapeutics selects first clinical candidate for immunotherapeutic treatment of Gram-negative bacterial infections
Centauri Therapeutics Limited has announced the selection of its first clinical candidate in the ABX-01 programme. The compound is designed to target serious Gram-negative bacterial infections in the lung.
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NewsScientists track pneumonia-causing bacteria as they infect the blood stream
A new study has shown various dissemination patterns can be adopted by Klebsiella pneumoniae that causes systemic infection, i.e. bacteremia.
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NewsCold sore discovery IDs unknown trigger for those annoying flare-ups
Scientists have a new target to prevent cold sores after researchers discovered an unexpected way that the herpes virus re-activates in the body. The finding could also have important implications for genital herpes caused by the same virus.
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NewsExperts recommend mAb protection against RSV as standard care for all infants
While RSV poses a serious threat to the health of infants and young children, prophylactic mAbs offer safe and effective protection for an entire season, according to international health organizations.
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NewsImmunity against seasonal H1N1 flu reduces bird flu severity in ferrets, study suggests
Pre-existing immunity against seasonal H1N1 flu might help explain why most reported human cases of H5N1 bird flu in the U.S. have not resulted in lethal outcomes, suggests a new study.
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NewsNew insights into how specific gut cells respond to bacterial toxins
Researchers have characterized a specific gut cell type, BEST4/CA7+ cells, with the ability to interact with immune cytokine interferon-γ (IFNγ), and its regulation in cellular electrolyte and water balance, in response to bacterial toxins.
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NewsBacteria consumed by immune cells become part of the cell
Immune cells that eat bacteria in the body don’t stash them in specialized compartments as once thought, but turn them into critical nutrients that build proteins, create energy and keep the cells alive, according to a new study.
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NewsStudy reveals how bacteria in microbiome medicine trigger tumor-killing cells
Microbiotica has presented new data on the mechanism of action of MB097, a clinical-stage drug candidate being developed as a co-therapy in combination with KEYTRUDA® (pembrolizumab) in patients with advanced melanoma.
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NewsNeutrophil-to-lymphocyte ratio and its correlation with tuberculosis infection
A new study reveals a significant negative correlation between neutrophil-to-lymphocyte ratio (NLR) and the risk of tuberculosis infection (TBI), particularly in males and individuals with hypertension.
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NewsHerpesviruses may contribute to Alzheimer’s disease via transposable elements
Researchers have outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer’s disease in aging brains, and also share two FDA-approved, commercially available drugs that reverse this pathway in a laboratory setting.
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NewsAs dengue spreads, researchers discover a clue to fighting the virus
Children who experience multiple cases of dengue virus develop an army of dengue-fighting T cells, according to a new study. Most children who experienced two or more dengue infections showed very minor symptoms—or no symptoms at all—when they caught the virus again.