All Immunology articles – Page 2
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Key influenza-severity risk factor found hiding in plain sight on our antibodies
Viruses are the fastest-evolving biological entity on earth. This fact explains why we need flu shots every year: Seasonal influenza perennially outwits the immunity we’ve acquired from previous vaccinations or infections. Source: Yuki999 H1N1 virus Some new strains are rougher than others. The 1918 flu pandemic killed ...
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Scientists exploit shape change to reveal how immune cells sniff out pathogens
Researchers are using an innovative method to watch immune receptors go about their business, based on the fact that cells tend to change their form when they come into contact with a signal molecule.
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SARS-CoV-2 ‘steals’ our proteins to protect itself from the immune system
Researchers at the Medical University of Vienna and the Medical University of Innsbruck discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity. This significantly impairs viral clearance which may affect the course of ...
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Faster measurement of response to antibiotic treatment in sepsis patients using Dimeric HNL
The biomarker human neutrophil lipocalin HNL, which was previously shown to be a useful indicator of bacterial infections, may also in the form of Dimeric HNL be used to effectively monitor the success of antibiotic treatment in sepsis.
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Gut microbiome changes linked to onset of clinically evident rheumatoid arthritis
Changes in the make-up of the gut microbiome are linked to the onset of clinically evident rheumatoid arthritis in those at risk of the disease because of genetic, environmental, or immunological factors, suggests a new study.
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Repeated COVID vaccines enhance mucosal immunity against the virus
New work has found that repeated Covid-19 vaccinations lead to the presence of mucosal antibodies, for example, inside the nose.
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Novel antibody platform tackles viral mutations
Scientists have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.
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Study uncovers how Covid-19 is so good at defeating the innate immune response
The novel coronavirus SARS-CoV-2 has an enzyme that can counteract a cell’s innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses.
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New international research alliance to tackle Mpox epidemic in Africa
MpoxVax AFRIVAC is a new €1.3 million international consortium that aims to rapidly deploy technology and develop new knowledge to end the current Mpox outbreak in the Democratic Republic of Congo (DRC) and surrounding countries.
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Scientists discover new process to drive anti-viral immunity
Scientists have discovered a new process in our immune systems that leads to the production of an important family of anti-viral proteins called interferons.
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Scientists discover how innate immunity envelops bacteria
The human protein GBP1 fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now. Researchers have unravelled how this protein operates.
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Researchers identify signs tied to more severe cases of RSV
In a new study, researchers found an increase in NK cells in the airways of children with severe RSV as well as other alterations that suggest these cells may be contributing to disease severity.
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Scientists discover viral trapdoor blocking HIV and herpes
A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them ...
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Rates of a tick-borne parasitic disease are on the rise
Cases of babesiosis increased 9% per year, on average, between 2015 and 2022 and nearly half were co-infected with another tick-borne illness such as Lyme disease, according to a new study.
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Antibodies in breast milk provide protection against common GI virus
A study has found that breast milk provides protection against rotavirus, a common gastrointestinal disease that causes diarrhea, vomiting and fever in infants.
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Could a bout of COVID protect you from a severe case of flu?
More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime. Does an encounter with one virus influence how your immune system responds to a different one?
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Researchers discover mechanism driving immune perturbations after severe TB infections
Rsearchers have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated.
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Getting the flu and then your shot may benefit immunity
In a new study, researchers have found that natural immunity from previous flu infections has a significant impact on how well future influenza vaccinations work.
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Immunotherapy for gum disease? Study in mice shows promise
Delivering microparticles containing the immune-modulating compound CCL2 directly to the gums inhibited bone loss and sped up bone repair in a mouse model of periodontal disease, new research has found.
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MMR vaccine still best protection against measles - modelling study suggests level of protection decreases slightly over time
A new study shows the MMR vaccine remains the best protection against measles. The modelling study in England suggests level of protection decreases slightly over time.