All Immunology articles – Page 16
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New research points out ways to improve tuberculosis vaccines
A new study unveils a previously unappreciated role for a class of immune cells in the early stages of tuberculosis (TB) infection.
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Coronavirus vaccination reveals that body builds immune memory in organs
A study of the mRNA coronavirus vaccines reveals that the human body builds local immune memory in various organs. The immune memory cells are more numerous in the organs than in the blood and have enhanced antiviral defense functions.
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Microbiome molecule may hamper immune cells’ cancer-fighting abilities
An important group of immune cells in the large bowel - gamma delta T cells - are crucial to preventing bowel cancer, but a molecule linked to gut microbiome diversity may suppress their immune response.
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Fungal toxin triggers NET traps formed by white blood cells
A new study sheds light on how neutrophils respond to C. albicans hyphae, which release a peptide toxin called candidalysin, exclusively secreted when C. albicans grows as hyphae and hence during invasive growth.
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Prior exposure to common virus shields against birth defects and miscarriage
A new study uncovers how pre-existing immunity to Cytomegalovirus (CMV) may significantly reduce the risk of birth defects and miscarriage during pregnancy, offering hope for a future vaccine.
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Vulnerability to different COVID-19 mutations depends on previous infections and vaccination
A person’s immune response to variants of SARS-CoV-2 depends on their previous exposure – and differences in the focus of immune responses will help scientists understand how to optimise vaccines in the future to provide broad protection.
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Versatile vaccine candidate fights measles, mumps and Covid
Altered measles and mumps viruses could be used as a platform to create a trivalent COVID-19 vaccine that triggers immunity to multiple variant strains of the SARS-CoV-2 virus, new research in animals suggests. The study builds upon previous studies that involved inserting a highly stable segment of ...
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Leishmania’s secret weapon is ability to infect non-immune cells
The parasites that cause visceral leishmaniasis appear to have a secret weapon, new research suggests - they can infect non-immune cells and persist in those uncommon environments.
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Contagious omicron strain replicates early in infection
New research used engineered mice to compare SARS-COV-2 omicron subvariants and found one of them – BA.5 – was more virulent likely due to its ability to rapidly replicate early during infection.
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COVID-19 could hold key to spotting viruses with pandemic potential
Certain SARS-CoV-2 variants of concern are evolving to do a better job of shutting down human innate immune responses, according to new research.
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Proteins in breast milk found to be essential for a baby’s healthy gut
A new study shows variation in the protein composition of breast milk between mothers explains much of the variation in the abundance of key beneficial microbes in the gut of their babies.
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Hypervirulent bacteria emerging in healthy people
New ’hypervirulent’ strains of the bacterium Klebsiella pneumoniae have emerged in healthy people in community settings, prompting researchers to investigate how the human immune system defends against infection.
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Study IDs secret of stealthy invader essential to ruinous rice disease
The virulence of a rice-wrecking fungus — and deployment of ninja-like proteins that help it escape detection by muffling an immune system’s alarm bells — relies on genetic decoding quirks that could prove central to stopping it.
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Energy depleting mechanism immunizes bacteria against phages
Researchers have described a new family of proteins that deplete cells of their energy, thereby protecting the cells from invaders. The previously unknown immune mechanism is used by many living creatures, from bacteria to bees.
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Common cold virus exposure may help usher in immunity to Covid
Exposure to common cold-causing coronaviruses may contribute to pre-existing immunity to COVID-19, according to a new study.
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Spike protein mutants with low binding affinity usher in new Covid vaccine
Researchers have succeeded in producing a new vaccine against the SARS-CoV-2 coronavirus by identifying spike protein mutants that lack binding affinity.
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Interferon could help reduce the spread of COVID-19
Results of an innovative clinical trial have shown that the drug interferon could help reduce the spread of COVID-19 from a positive person to their household contacts, with the study helping to inform treatment options for a future pandemic.
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Immune systems develop ‘silver bullet’ defences against common bacteria
Immune systems develop specific genes to combat common bacteria such as those found in food, new research shows.
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High-res map of the human placenta reveals COVID virus hideouts
Researchers have developed a high-resolution map of the human placenta visualizing an array of different immune microenvironments in healthy placentas from uninfected pregnancies, and those from pregnancies affected by COVID infections.
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Researchers reveal how Leishmania parasite uses immune cells as Trojan Horse
A new study found that the parasite targets a receptor on the surface of the neutrophil to gain access to the cell, and once inside the parasite resists the neutrophils’ pathogen-killing molecules.