All Immunology articles – Page 15
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B cell deficient patients gain protective T cell immunity after SARS-CoV-2 vaccination, infection
Researchers found that vaccinated B cell-deficient individuals had significantly reduced risk of moderate and severe disease in comparison to those who were not vaccinated, despite an absence of anti-spike antibody responses.
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Researchers ID opportunities to improve future HIV vaccine candidates
An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study.
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Multiple sclerosis: Possible basis for vaccine researched
Researchers have shown that the risk of MS is particularly high in people with a combination of certain host factors and variants of the Epstein-Barr virus (EBV).
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Study reveals how the immune system fights to keep herpes at bay
A recent study, conducted using lab-engineered cells, unveils the precise maneuvers used by host and herpes simplex virus (HSV) in the fight for dominance of the cell.
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Risk of death reduces after COVID-19 vaccine but protection wanes after six months
The risk of death from COVID-19 decreases significantly after vaccination but this protection diminishes after six months, providing evidence for continued booster doses, a new study has found.
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Mpox vaccine triggers equally strong immune response in smaller doses
Delivering the two-dose mpox vaccine in smaller than the usual FDA-approved doses produced a detectable immune response. This also occurred regardless of whether people were living with or without HIV.
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Patients can pause immune-suppressing medicines for COVID-19 booster vaccine
A major clinical trial shows that people with inflammatory conditions are able to improve the antibody response from a COVID-19 booster vaccination by interrupting their treatment for two weeks immediately after having the vaccine.
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T cells tackle new ‘Pirola’ SARS-CoV-2 variant
Scientists harness bioinformatics to predict how T cells may adapt to fighting the highly mutated Pirola variant.
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Covid persistence in lungs linked to failure of innate immunity
A new study shows that SARS-CoV-2 is found in the lungs of certain individuals for up to 18 months after infection, and that its persistence appears to be linked to a failure of innate immunity (the first line of defense against pathogens).
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Fungus-fighting protein could help overcome severe autoimmune disease and cancer
A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS) and type 1 diabetes.
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Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses
Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body, and have found a way to prevent ‘off-target’ immune responses.
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Very early antiretroviral therapy within hours of birth could suppress HIV in newborns
A study of more than 50 babies through 2 years old supports evidence that giving antiretroviral therapy (ART) to newborns with HIV within the first days of life can safely suppress amounts of HIV in the blood to undetectable levels.
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Broccoli molecule could shape immune defense against Cryptosporidium
Researchers have discovered that a common dietary supplement could protect against chronic Cryptosporidium infections which are particularly prevalent in children under two and in areas with poorer sanitation.
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Pathogens use force to breach immune defenses, study finds
Researchers have discovered a previously unknown process by which pathogens enter a cell with physical force, breaching the body’s immune defenses that prevent infection.
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Scientists boost vaccines with machine learning to drive more effective treatments
Machine learning guided the discovery of new immune pathway-enhancing molecules and found one particular small molecule that could outperform the best immunomodulators on the market.
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Fourth dose of COVID vaccine boosts protection in patients with rheumatic disease
A new study suggests that the recommendation for patients receiving disease-modifying antirheumatic drugs to receive a fourth dose of the mRNA vaccine has saved lives and reduced hospitalizations among patients in this high-risk group.
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Study uncovers mediators of persistent HIV viremia
Researchers examining people with non-suppressible HIV viremia (NSV) despite receiving antiretroviral therapy (ART) have found large reservoirs of proviruses inserted into transcriptionally active regions of immune cell genomes.
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Alert immune system in respiratory tract protects children from severe Covid
Scientists have discovered that the immune system in the upper respiratory tract is much more alert and active in children before infection than in adults and is therefore better equipped to fight the virus.
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Scientists find an unusual weapon against human cytomegalovirus
Instead of targeting the virus with antiviral treatments, the researchers focused on strengthening the immune system to fight the virus on its own.
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Bat immune genes protect against COVID and cancer
Bats have acquired remarkable traits throughout their evolution. They’re the only mammals that can fly, and they live much longer than other animals their size. But perhaps most impressive is their robust immune system. It protects bats from viruses that wreak havoc in humans, like COVID-19 or Ebola, and also ...