All Immunology articles – Page 12
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Experts developing immune-enhancing therapies to target tuberculosis
Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body’s own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.
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Lower dose of mpox vaccine is safe and generates six-week antibody response equivalent to standard regimen
A dose-sparing intradermal mpox vaccination regimen was safe and generated an antibody response equivalent to that induced by the standard regimen at six weeks (two weeks after the second dose), according to new findings.
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Study confirms effectiveness of bivalent COVID-19 vaccine
A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to a new study.
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Experimental NIH malaria monoclonal antibody protective in Malian children
One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country’s six-month malaria season, according to the results of a mid-stage clinical trial.
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Vitamin D availability enhances antitumor microbes in mice
Dietary vitamin D modulates the gut microbiome to enhance the response to cancer immunotherapies, according to a new study in mice.
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Researchers use AI to improve Alzheimer’s treatment through the ‘gut-brain axis’
Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer’s disease.
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Pathogens deploy speargun nanomachine to spread unrecognized in the body
Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.
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Gut bacteria can change their ‘software’ in reaction to inflammation
New research reveals an ingenious adaptation strategy used by gut microbes, allowing them to dynamically reprogram gene expression based on local conditions like inflammation or viral attacks.
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Researchers uncover new reasons to target neutrophils for tuberculosis therapy
Using cell models of infection, scientists examined the cross-talk between two lung immune cells: the macrophage and the neutrophil.
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Small protein plays big role in chronic HIV infection
Using a mouse model of neuroHIV, researchers studied the effects of interferon-β (IFNβ), a small protein involved in cell signaling and integral to the body’s natural defense mechanism against viral infections.
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Study shows Mpox (monkeypox) antibodies wane within a year of vaccination
New research shows that the antibodies produced by Modified Vaccinia virus Ankara - Bavarian Nordic (MVA-BN) vaccination against mpox wane significantly within a year of receiving the vaccination.
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Significant decline of neutralising antibodies to monkeypox virus during the first month after vaccination
New research shows that even in men who receive two doses of mpox vaccine intradermally, their level of antibodies to the virus falls to low or zero within the first few months if they have not received a previous smallpox vaccine.
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Study maps main genes involved in immune response to infection by dengue virus
Researchers compared data for the immune response induced by natural infection and vaccines. They identified the key factors in the development of long-lasting immunity.
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Gut bacteria make neurotransmitters to shape the newborn immune system
Investigators discovered that unique bacteria colonize the gut shortly after birth and make the neurotransmitter serotonin to educate gut immune cells. This prevents allergic reactions to food and the bacteria themselves during early development.
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Gut bacteria important for overcoming milk allergy
Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences in Japan have discovered a link between gut bacteria and the success of milk-allergy oral immunotherapy. Published in the scientific journal Allergology International, the study found that Bifidobacterium—a genus of beneficial bacteria in the ...
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Tryptophan in diet and gut bacteria team up to protect against E. coli infection
Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure, according to a new study.
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Study shows important role gut microbes play in airway health in persons with cystic fibrosis
Findings from a new study conducted by a team of researchers at Dartmouth’s Geisel School of Medicine and published in the journal mBio, reflect the important role that the gut microbiome (communities of bacteria) plays in the airway health of persons with cystic fibrosis. Source: CDC/ Dr. ...
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New understanding of the gut immune system may hold promise for Crohn’s disease patients
A team of scientists have uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn’s disease. The discovery may help define how to treat patients with severe Crohn’s disease.
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Scientists show how COVID mRNA vaccines reshape immune memory after each dose
Researchers show that T cells can reshape their memory and maintain diversity against different COVID variants in response to successive mRNA vaccinations.