All Immunology articles
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Study: Experimental bird flu vaccine excels in animal models
A vaccine has demonstrated complete protection in mice against a deadly variant of the virus that causes bird flu. It focuses on the H5N1 variant known as 2.3.4.4b, which has caused widespread outbreaks in wild birds and poultry.
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Gut microbes release cancer-fighting bile acids that block hormone signals
Bacteria naturally present in the human intestine can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study.
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Researchers explore gut microbiota’s role in sleep apnea in new review
A new scientific review highlights emerging connections between gut health and sleep apnea, pointing to potential new therapeutic approaches for managing this common and serious disorder.
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Study finds immune protein modification blocks viral replication, heart inflammation
New research shows protein modifications to the immune sensor MDA5 reduce viral replication and may lead to broad-spectrum antiviral breakthroughs.
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Gut microbes could one day be deployed to tackle sleepless nights: review
Personalized pre/probiotic treatments could someday be used to support healthy sleep through stressful exam periods and menopause, a new review suggests.
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Bad breath, bad news: how gum disease could worsen liver conditions
A review discusses the close association of oral health and liver diseases, since oral pathogens and their factors can translocate to liver through the gastrointestinal tract and exacerbate chronic liver conditions in multiple ways, as supported by animal and clinical studies.
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Fiber consumption protects gut from serious bacterial infection, study suggests
Brazilian researchers have gained better understanding of the role of soluble dietary fibre in the mechanism of immune modulation and fight against gut pathogen Clostridioides difficile that causes severe diarrhoea and colon inflammation.
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COVID-19 vaccination induces long-lasting antibody B-cell responses
A research study revealed that memory B cells maintain long-lasting and stable responses prior to mRNA vaccinations for COVID-19, but updated vaccines targeting new variants could boost immunity.
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Viral ‘backbone’ underlies variation in rotavirus vaccine effectiveness
A new study has shown that full-genome differences between rotavirus strains influence vaccine effectiveness, highlighting the need for a broader approach to vaccine design.
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Tackling the ‘silent pandemic’: breakthrough study puts first long COVID treatment on horizon
Researchers have shown a new drug compound can prevent long COVID symptoms in mice – a landmark finding that could lead to a future treatment for the debilitating condition.
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Bacteria-enhanced graphene oxide nanoparticles for triple-action tumor eradication
Researchers developed graphene oxide nanoparticles that combine chemotherapy, immune activation, and photothermal heating to effectively destroy tumors. The novel GO nanocomposite is enhanced with bacterial components.
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Researchers discover way to predict treatment success for parasitic skin disease
Researchers have discovered a way to predict whether a patient suffering from cutaneous leishmaniasis will respond to the most common treatment, potentially saving patients from months of expensive, ineffective and toxic medication.
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Molecular stool test could improve detection of tuberculosis in adults with HIV
A prospective multicentre study highlights the potential of the Xpert MTB/Ultra stool test for diagnosing tuberculosis in people living with HIV.
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Molecules that fight infection also act on the brain, inducing anxiety or sociability
New research on a cytokine called IL-17 adds to growing evidence that immune molecules can influence behavior during illness.
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Researchers reveal why young plants may be more vulnerable to disease
A new study on baby plants shows that fighting disease at a young age often comes at a steep cost to growth and future evolutionary fitness—or their ability to reproduce.
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Alternative approach to Lyme disease vaccine development shows promise in pre-clinical models
An international research team finds genetically engineered Lyme bacterial proteins could offer long-standing protection against infection while requiring fewer vaccinations.
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Western diet causes inflammation, traditional African food protects
A study showed that traditional African diets, rich in fiber, fermented food and vegetables, have higher health benefits that boost immunity and reduce the risk of developing lifestyle diseases, compared to the high calorie and high saturated fats in the Western diet.
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mRNA-based COVID-19 vaccines train the ‘long-term memory’ of the innate immune system
A study showed that vaccination of multiple mRNA-based COVID-19 vaccines could induce persistent epigenetic changes in innate immune cells, leading to long-term immune responses for SARS-CoV-2 and other pathogens.
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‘It’s a shot, not a vaccine like MMR’: New skepticism prompts call for action
This ‘vaccine is not a vaccine’ is a new, previously unreported type of vaccine-specific scepticism, and it arose only during the COVID-19 pandemic. However, it might, according to the researchers, also apply to the flu vaccine.
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Susceptibility to bovine TB in cattle traced to key genes
A new study identifying genetic factors contributing to bovine tuberculosis (bTB) susceptibility has found several key genes and pathways involved in the bovine response to Mycobacterium bovis, the causative agent of the disease in cattle.