All Immunology articles
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Machine learning framework can decipher immune system’s record of past infections
A novel machine learning framework can decipher an individual’s immune system’s record of past infections and diseases, providing a powerful tool with the potential for diagnosing autoimmune disorders, viral infections, and vaccine responses with precision.
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Researchers ID key immune differences that make one West African ethnic group less susceptible to malaria
Researchers have uncovered how genetic and lifestyle factors influence immune responses to malaria in children from two large West African ethnic groups. Children showed key differences in immune cell activity offering greater protection.
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Fungal compound could help protect against influenza
A preclinical trial uncovers how beta-glucan, a compound found in all fungal cell wall, can ‘reprogram’ immune cells to prevent lung inflammation from influenza and lower the risk of death by the host immune responses.
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Mass polio vaccination campaign to continue in the Gaza Strip
The emergency polio outbreak response in the Gaza Strip is continuing, with a mass vaccination campaign scheduled from 22 to 26 February 2025. The novel oral polio vaccine type 2 (nOPV2) will be administered to over 591,000 children under 10 years of age.
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Scientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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Evolutionary tradeoffs: Research explores the role of iron levels in COVID-19 infections
Iron has been found to be essential to both human physiology and pathogen replication. The richer the iron availability, the more likely to be susceptible to infections, such as COVID-19. A balance of iron levels is thus critical for homeostasis and preventing pathogenic infections.
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Fungus ‘hacks’ natural immune system causing neurodegeneration in fruit flies
A fungus, called Beauveria bassiana, is found to manipulate the innate immunity of the fruit flies to attack their own brain cells, causing the penetration into the blood-brain barriers and eventually neurodegeneration.
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Scientists harness microbiota as ally for predicting individual sensitivity to food additives
Researchers developed a human microbiota modelling system capable of predicting each person’s sensitivity to an emulsifier, using a simple stool sample, paving the way for a personalised nutrition approach based on the gut microbiota.
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Harvard Pilgrim Health Care Institute announces launch of Center for Sepsis Epidemiology and Prevention Studies (SEPSIS)
The new Center for Sepsis Epidemiology and Prevention Studies (SEPSIS) is a pioneering center of excellence dedicated to advancing understanding, prevention, and management of sepsis, a life-threatening condition caused by a dysregulated immune response to infection.
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From Spanish flu to today: how immune cells keep up with a changing virus
In a breakthrough for influenza research, scientists have discovered immune cells that can recognise influenza (flu) viruses even as they mutate, raising hopes for a longer-lasting vaccine and a universal protection against future flu pandemics.
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Breakthroughs in TB vaccine and drug development pave way for global health advancements
An international team of researchers unveils groundbreaking progress in TB vaccine development and therapeutic innovations, offering hope to curb the disease’s devastating impact.
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Bat genome signposts new potential pathway to fight viruses with genomic characterization
A promising discovery has been made from a study that deciphers how bats are more resistant to viral infections than human using genome annotations of transposable elements in bats to pave a way for adapting the bats’ immunity against future viral outbreaks.
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First success in overcoming gene therapy challenges deploys nanomachines loaded with wine ingredients
Scientists have demonstrated the ability to overcome significant challenges in gene therapy using adeno-associated virus vectors (AAV) by employing a novel smart nanomachine equipped with AAV.
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Study shows some species are susceptible to broad range of viruses
A study of fruit flies shows some species are highly susceptible to a wide range of viruses. But fly species that were resistant to one virus were generally resistant to others – including very different types of virus.
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New method offers faster response to new virus variants
Researchers present a promising approach for swift identification of mutations that are crucial for the immune escape that enables the rapid adaptation of vaccines to new virus variants. It is based on a previously established method called mutational scanning.
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Infant gut bacteria and food allergies: the good, the bad, and the ugly
A research study delves into the associations between neonatal gut microbiota compositions and food allergies, in order to find a way to improve infants’ immunities.
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Scientists probe honeybee antiviral defense mechanisms
Scientists are investigating honeybee antiviral defense mechanisms with the goal of developing strategies to reduce honeybee colony deaths.
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Why you shouldn’t scratch an itchy rash: New study explains
New research uncovers how scratching aggravates inflammation and swelling in a mouse model of a type of eczema called allergic contact dermatitis.
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Antibody treatment prevents severe bird flu in monkeys
A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, a new study reports.
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Researchers in Brazil discover a gene that may afford protection against COVID-19
During the pandemic, health worker Maria Tereza Malheiros Sapienza’s curiosity was aroused by her immunity to SARS-CoV-2, even though her husband was infected twice. A new study reveals that an overexpression of IFIT3 protein was responsible.