All Immunology articles
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New treatment targets link between viral infection and Alzheimer’s disease
A unique mechanism triggering Alzheimer’s disease draws attention: viral infection—while ALT001 is confirmed to alleviate neuroinflammation and suppress viral replication.
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Particles carrying multiple vaccine doses could reduce the need for follow-up shots
Researchers are working to develop microparticles that can release their payload weeks or months after being injected. This could lead to vaccines that can be given just once, with several doses that would be released at different time points.
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Two HIV vaccine trials show proof of concept for pathway to broadly neutralizing antibodies
A new study combining data from two separate phase 1 clinical trials shows that a targeted vaccine strategy can successfully activate early immune responses relevant to HIV, and, in one trial, further advance them.
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Scientists find two brain biomarkers in long COVID sufferers may be what’s causing brain fog
A new study that compares inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows those with cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.
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Yellow fever vaccination: how strong immune responses are triggered
Researchers have shown how specific immune cells are activated by the vaccine – an important starting point for the development of new vaccines.
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Scientist awarded $500,000 Gruber Genetics Prize for pioneering discoveries in bacterial immune systems
The 2025 Gruber Genetics Prize is being awarded to geneticist and molecular biologist Rotem Sorek, Ph.D., of the Weizmann Institute of Science, for his discoveries in the immune system of bacteria.
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Researchers reveal lipid-based communication between body and gut microbes
A new study shows how a host protein can specifically recognize bacterial lipids, thus triggering beneficial immune responses. It also highlights a new way the body actively shapes the gut microbiome by communicating with microbes to maintain balance.
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‘Loop’hole: HIV-1 hijacks human immune cells using circular RNAs
In a groundbreaking discovery, researchers have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body’s natural defenses and use it to support its survival and replication.
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Scientists reveal key bacterial immune mechanism
Researchers have uncovered a pivotal mechanism by which bacteria defend themselves against viral infection. Cyclic dinucleotides (CDNs), synthesized during activation of the cyclic oligonucleotide-based anti-phage signaling system (CBASS) immune mechanism, trigger the filamentous assembly of phospholipase effectors, which execute the downstream immune response.
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New study offers insights into designing safe, effective nasal vaccines
Researchers found that nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, even without the help of immune-boosting ingredients known as adjuvants. The findings, researchers suggest, may offer critical insights into developing safer, more effective nasal vaccines in the future.
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New discovery explains why men are more affected by severe COVID-19
Researchers have found another piece of the puzzle that explains why there are differences in immune responses in women and men when they get sick with COVID-19. This discovery has implications for treatment strategies for severe COVID-19.
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New vaccine protects against swine, human and bird flu
Annual flu shots could become a thing of the past under a new vaccine strategy. A new study describes a vaccine that protects against H1N1 swine flu and can also protect against influenza in humans and birds.
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COVID-19 caused by the Omicron variant in lung transplant recipients: a single center case series
A new study investigates the risk factors for developing severe disease in lung transplant patients as a result of the Omicron variant of Covid-19.
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Heart rhythm disorder traced to bacterium lurking in our gums
A new study finds that a gum disease bacterium can slip into the bloodstream and infiltrate the heart. There, it drives scar tissue buildup—known as fibrosis—distorting the heart’s architecture, interfering with electrical signals, and raising the risk of atrial fibrillation (AFib).
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Researchers reveal how fungi ‘manipulate’ the course of tumors
In pancreatic ductal adenocarcinoma (PDA), the abnormal colonization of fungal communities has become a research hotspot. New research indicates that Malassezia is not only a ’marker’ in the tumor microenvironment but also a potential driver of cancer development.
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Forever chemicals influence cellular immune response to coronavirus
A new study shows that PFAS influence the cellular immune response to coronavirus and also reveals sex-specific differences as to how the immune system reacts to the virus.
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Predictive AI model can help build vaccines for future versions of a virus
Researchers have created an AI tool called EVE-Vax that can predict and design viral proteins likely to emerge in the future. For SARS-CoV-2, panels of these “designer” proteins triggered similar immune responses as real-life viral proteins that emerged during the pandemic.
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Scientists engineer antibody against flu with sticky staying power
Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a mature flu fighter with the broad binding capacity of a more general immune system defender. Source: NIAID Colorized transmission ...
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Viruses under the super microscope: How influenza viruses communicate with cells
Scientists have characterized a new model of influenza A infection: binding to MHC class II complexes as an alternative receptor and the associated dynamic reorganization of the cell surface.
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Silver nanoparticles produced by fungus could be used to prevent and treat COVID-19
Silver nanoparticles produced by the fungus Trichoderma reesei could become important allies in the prevention and treatment of COVID-19. Tests on hamsters showed that they not only inhibited the infection but also reduced the viral load in the lungs.