All I‐A CRISPR articles
-
NewsResearchers develop an efficient host-vector system for a model archaeon by solving CRISPR-based host-plasmid conflict
The replicase gene of pRN1, an archaeal cryotic plasmid, carries a DNA segment to be targeted by the host I‐A CRISPR system, and the CRISPR-based host-plasmid conflict is responsible for instability of pRN1‐derived vectors in the archaeon Saccharolobus islandicus REY15A.
