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Chemists pioneer metallodrug-antibiotic combination strategy to combat superbugs
A combination of different types of antibiotics with bismuth-based drugs, such as Pepto-Bismol, disrupts bacterial iron homeostasis, effectively restoring the bactericidal function of multiple antibiotics.
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Scientists pioneer dual trojan horse approach to combat superbugs
In the relentless battle against antibiotic-resistant superbugs, science continues to unveil ingenious strategies to address their vulnerability. Like other bacteria, superbugs have a unique weakness – their dependence on iron for growth and survival. Iron serves as an essential nutrient that bacteria utilise for various cellular processes, including DNA replication, ...