All HIV articles – Page 3
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Novel vaccine concept generates immune responses that could produce multiple types of HIV broadly neutralizing antibodies
Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals’ immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs). The findings, published in Nature Immunology, are an encouraging, incremental step in developing a preventive HIV vaccine. ...
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Researchers deliver boost for HIV vaccine research
Scientists have developed a comprehensive platform for HIV vaccine research capable of both preclinically validating next-step boost immunogens and providing new insights into the basic biology of the antibody response.
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A trial HIV vaccine triggered elusive and essential antibodies in humans
An HIV vaccine candidate triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.
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Advances in priming B cell immunity against HIV pave the way to future HIV vaccines, new studies show
Scientists have made several advances in the design of a class of HIV vaccines that could offer broad protection against the virus, according to four new research papers published this week.
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Scientists trace source and spread of HIV variant in Indonesia
A new study traces where the dominant HIV variant in Indonesia came from and how it spread from there, offering insights of possible value to the development of treatments against the disease.
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Keto diet boosts lifesaving antifungal drug in mice
In animal tests, researchers have found that taking fluconazole in combination with a low-carb, high-fat keto diet worked significantly better at killing the fungus behind fungal meningitis than taking the medication alone.
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GPS-like system shows promise as HIV vaccine strategy to elicit critical antibodies
Researchers have developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against HIV.
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US geographic region results in vastly different anal cancer risk for people with HIV
A new study that followed a cohort of more than 110,000 people establishes significant disparities in the risk of anal cancer for people with HIV, depending on the region of the country they live in.
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Global study reveals stark differences between females and males in major causes of disease burden
Globally, there are substantial differences between females and males (aged 10 and older) when it comes to health, with limited progress in bridging these health gaps over the past 30 years, according to a new study.
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Program receives grant to study causes of death in adults with HIV in Africa
A new grant will allow the CHAMPS network to leverage its laboratory capacity and partnerships in Africa to identify and document causes of death among adults who were living with HIV.
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Closing the U.S./Mexico border during COVID-19 increased HIV transmission
When the border crossing separating San Diego, California, from Tijuana, Mexico, was closed during the COVID-19 pandemic, drug tourism from San Diego to Tijuana continued, providing a flow of people in both directions.
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Celebrity weight-loss drug helps people with HIV fight fatty liver, study shows
Scientists have found that a medication used to treat diabetes and obesity – and touted on social media for weight loss – can be a powerful weapon against a type of fatty liver disease in people with HIV.
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Study highlights importance of early interventions to combat HIV
Researchers have investigated the impact of treatment initiation timing on the characteristics of HIV reservoirs, a major obstacle to eradicating the virus.
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Perinatal transmission of HIV can lead to cognitive deficits
Perinatal transmission of HIV to newborns is associated with serious cognitive deficits as children grow older, according to a detailed analysis of 35 studies.
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COVID-19 increases the risk of severe cardiovascular problems in people with HIV
A study has revealed that people living with HIV who have experienced an episode of COVID-19 face a significant increase in the risk of cardiovascular diseases in the year following infection.
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New study uncovers why boys born to mothers with HIV are at greater risk of health problems and death in infancy
Researchers have found that children of women with HIV infection have an increased risk of immune abnormalities following exposure to maternal HIV viraemia, immune dysfunction, and co-infections during pregnancy.
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HIV epidemic cannot be ended without stopping former prisoners and other patients from being lost to care
A field implementation programme reveals challenges of locating and re-engaging former prisoners and other individuals living with HIV who drop out of care.
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Study confirms how RNA chemical modifications benefit HIV-1
A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus’s ability to survive and thrive after infecting host cells, a new study has found.
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ChatGPT could help reduce vaccine hesitancy and provide helpful advice on STIs
A pilot study shows the potential for using AI chatbots to assist public health campaigns in reducing vaccine hesitancy as well as providing helpful advice on STIs and access to care.
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Scientists ID pro-aging ‘sugar signature’ in the blood of people living with HIV
Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH).