All HIV articles
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News
Simulation model shows potential affordability of preventative HIV therapy for infants
A type of cost-effective HIV neutralizing antibodies was evaluated to prevent the viral infection in infants during breastfeeding in high HIV prevalance countries. This treatment option is comparatively cheaper and has high clinical impacts in high HIV burden settings to achieve global elimination.
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Japanese plant Daphne pseudomezereum yields anti-HIV daphnane diterpenoids
Scientists have discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).
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Study yields new data on Mpox vaccine effectiveness in people with HIV
A new study has found that a single dose of the Imvanex vaccine provides protection against Mpox with 84% effectiveness. For people with HIV, however, a single dose of the vaccine fails to offer sufficient protection. All at-risk groups, especially people with HIV, should receive the second dose of the vaccine as recommended.
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Researchers develop method to identify dormant cells that carry HIV
A new method is developed that utilizes a fluorescent genetic switch to tag and trace the lineages of the HIV-infected cells, including the dormant ones. This system might help to develop target therapies for the infected immune cells.
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New study highlights gaps in HPV-related cancer prevention for people living with HIV
A new study reveals gaps in knowledge surrounding the prevention of HPV-related cancers in people living with HIV and outlines future research priorities. It highlights existing disparities in healthcare for this vulnerable population.
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New paper-based device boosts HIV test accuracy from dried blood samples
Scientists have trialled a more precise medical device to measure HIV viral loads by engineering a paper device with wax-printed patterns that create precise channels and collection spots, ensuring it consistently collects the same volume of blood.
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Machine learning framework can decipher immune system’s record of past infections
A novel machine learning framework can decipher an individual’s immune system’s record of past infections and diseases, providing a powerful tool with the potential for diagnosing autoimmune disorders, viral infections, and vaccine responses with precision.
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New therapy may effectively control HIV in Uganda
Clinical trials showed an effective antiviral drug, known as lenacapavir, against HIV in Uganda, and has also been tested for drug resistance in different subtype strains.
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Transforming HIV diagnosis: a low-cost, point-of-care detection solution
A team of researchers has developed an innovative handheld device for human immunodeficiency virus (HIV) detection that combines paper-based sample preparation with real-time isothermal amplification.
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Scientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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Eliminating HIV funding program would lead to >600k deaths in South Africa alone: warning
A new analysis finds that eliminating PEPFAR would lead to 601,000 HIV-related deaths, 565,000 new HIV infections, and would increase population-level healthcare expenditure by $1.7 billion over the next decade in South Africa alone.
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Hepatitis B is a problem for a growing number of patients on immunosuppressive medications
The American Gastroenterological Association (AGA) has unveiled an updated clinical practice guideline addressing the prevention and management of hepatitis B virus reactivation (HBVr) in patients on immunosuppressive drugs.
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New study finds social programs could reduce the spread of HIV by 29%
Researchers have found that addressing barriers to HIV care from depression, homelessness, individual and neighborhood poverty, education disparities, lack of insurance and unemployment could reduce the national HIV incidence by 29% over 10 years.
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Decoding HIV genomic tactics in viral replication
Research on HIV-1 unravels the viral and host translational regulations during viral replications through the identification of RNA structures and previously unrecognized genetic elements - this could bring potential therapeutic interventions to counter the viral manipulations.
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Chain reaction: HIV vaccines can lead to antibodies against antibodies
Scientists have discovered that repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus—knowledge that could lead to better vaccines.
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Climate change linked with worse HIV prevention and care
Researchers find that climate change and extreme weather events impact HIV prevention and care through numerous pathways, including increased HIV exposure, reduced testing, and worse health outcomes for people living with HIV.
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After lockdown, immune system reacts more strongly to viruses and bacteria
The lockdowns during the COVID-19 pandemic had a significant impact on people’s immune response to microorganisms. During the lockdown, inflammation level in the body was low, but afterwards, the immune system reacted more intensely to viruses and bacteria.
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New guidelines unveil advanced strategies for HIV treatment and prevention
The International Antiviral (formerly AIDS) Society-USA (IAS-USA) has published new international guidelines for the treatment and prevention of HIV, based on significant advances in antiretroviral therapies and new prevention strategies such as pre-exposure prophylaxis.
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Breakthrough of the Year: A drug that prevents HIV infection, providing six months of protection per shot
As its 2024 Breakthrough of The Year, Science has named the development of lenacapavir – a promising new injectable drug that prevents HIV infection. The award also recognizes related work surrounding gaining a new understanding of the structure and function of HIV’s capsid protein.
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New study highlights efficiency in detecting infectious diseases
In an effort to make large-scale disease testing faster and more affordable, researchers have developed an optimized approach to pooled testing, which could transform public health screening for infectious diseases.