All Gut Microbiome articles – Page 13
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Gut bacteria metabolite shows promise for fighting inflammatory bowel disease
A new study highlights the molecular mechanisms underlying the anti-inflammatory effects of KetoC, a gut bacteria-generated linoleic acid metabolite, using mouse models.
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Key role found for gut epithelial cells in the defense against deadly diarrheal infections
A newly identified subset of intestinal epithelial cells act as both the major target and a key responder in a mouse model of gut infection by the bacteria Citrobacter rodentium.
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Engineers develop innovative microbiome analysis software tools
Since the first microbial genome was sequenced in 1995, scientists have reconstructed the genomic makeup of hundreds of thousands of microorganisms and have even devised methods to take a census of bacterial communities on the skin, in the gut, or in soil, water and elsewhere based on bulk samples, leading ...
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Microbiome studies help explore treatments for genetic disorders
Researchers have discovered a collection of molecular tools to rewrite DNA through an even more efficient and precise genome editing process. They are investigating the clinical development of a group of enzymes for sub-retinal injections.
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Researchers discover compounds produced by gut bacteria that can treat inflammation
Researchers have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues.
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Research on how chickens fight salmonella offers clues to help other animals and humans
A paper published this spring is the culmination of decades of research that has uncovered the secrets of the chicken’s microbiome and changed the way the poultry industry tackles salmonella.
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Study reveals worrying links between bacteremia and probiotic use
Researchers using whole-genome sequencing found that all identified Clostridium butyricum bacteremia strains were probiotic derivatives.
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Father’s gut microbes affect the next generation
A study shows that disrupting the gut microbiome of male mice increases the risk of disease in their future offspring.
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Cranberry extracts could boost microbiota and counter cardiometabolic diseases
Cranberry extracts appear to improve intestinal microbiota and help prevent chronic diseases such as diabetes and cardiovascular diseases, according to a study that reported beneficial effects after only four days of use.
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Social connections and environmental contact spread different gut bacteria in wild mice
New research has revealed that the social connections of wild mice have a strong influence on the microbes found in their guts.
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Microbiome researchers challenge the state of the art in colon cancer biomarker discovery
For the first time, researchers from VIB-KU Leuven, UZ Leuven, Janssen Pharmaceutica and multiple international collaborators have introduced quantitative methods and extensive confounder control to discover microbiome biomarkers in colorectal cancer development. Source: VIB Dr. Raul Yhossef Tito-Tadeo, first author and postdoc at the Raes Lab (left) and ...
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Scientists reveal interaction mechanism between intestinal microbial environment and tumor immune microenvironment
Scientists have unveiled the mechanism of tumor immune evasion mediated by the microorganism C. scindens in colorectal cancer. Additionally, they developed a phage-based intervention method.
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Nonalcoholic fatty liver disease: changes in gut microbiota and blood lipids
This study aimed to explore differences in the gut microbial community and blood lipids between normal livers and those affected by NAFLD using 16S ribosomal deoxyribonucleic acid sequencing.
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Gut microbiome continually evolves as pregnancy progresses
A new study reveals the patterns of microbial dysbiosis associated with different pregnancy complications, providing an theoretical basis for elucidating the baseline characteristics of the microbiome in pregnant women.
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Cocktails of antibiotics, probiotics and prebiotics hold promise in treating a common form of irritable bowel syndrome
Personalised “cocktails” of antibiotics, probiotics and prebiotics hold great promise in the treatment of a common form of irritable bowel syndrome (IBS), a new study suggests.
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Vitamin D availability enhances antitumor microbes in mice
Dietary vitamin D modulates the gut microbiome to enhance the response to cancer immunotherapies, according to a new study in mice.
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Paclitaxel-induced immune dysfunction and activation of transcription factor AP-1 facilitate Hepatitis B virus replication
A study finds that Paclitaxel treatment directly promotes HBV replication and transcription, leading to HBV reactivation in HBV stable expression cell models, HBV natural infection cell models, and HBV transgenic mouse models.
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Major genetic meta-analysis reveals how antibiotic resistance in babies varies according to mode of birth, prematurity, and where they live
Meta-analysis of genetic studies from 10 countries finds infants born by C-section have more antibiotic resistance genes; antibiotic use and prematurity also fuel resistance.
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Artificial sweetener has potential to damage gut
New research has discovered that neotame, one of the new generation of artificial sweeteners, is capable of damaging the human intestine and causing illness.
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Gut microbiota acts like an auxiliary liver
Microbes in the mammalian gut can significantly change their hosts’ amino acid and glucose metabolism, acting almost like an extra liver, according to a new preclinical study.