All Georgia State University articles
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News
Gut bacteria composition influences rotavirus vaccine efficacy
Gut microbiota can influence rotavirus vaccine responsiveness and sometimes result in children remaining prone to rotavirus infection and severe disease despite having been vaccinated.
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Llama nanobodies deliver breakthrough in building HIV immunity
Scientists have developed a new antibody therapy that can neutralize a wide variety of HIV-1 strains. They found success in an unlikely source — llamas.
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Nanoparticle vaccines enhance cross-protection against influenza viruses
To offer cross-protection against diverse influenza virus variants, nanoparticle vaccines can produce pivotal cellular and mucosal immune responses that enhance vaccine efficacy and broaden protection, a new study reveals.
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Biotech companies leverage novel tools to develop drugs for RSV
Reporter structures that can be introduced into cells for use in drug screening assays emit fluorescent or bioluminescent light at different intensities when RSV genes are inhibited by the potential antiviral agents being tested.
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Severe lung damage caused when flu is followed by infection with measles-like virus
Infection with a measles-like virus causes catastrophic lung failure in ferrets previously infected with influenza virus or respiratory syncytial virus, according to a new study.
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Flu virus variants resistant to new antiviral drug candidate lose pathogenicity, study finds
Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, a new study has found.
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Gut microbiota influence severity of respiratory viral infection
The composition of microbiota found in the gut influences how susceptible mice are to respiratory virus infections and the severity of these infections, a new study reveals.
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Oral lipid nanoparticle drug can prevent development of colitis-associated cancer
An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by researchers in the Institute for Biomedical Sciences at Georgia State University. The findings published in the journal Pharmaceutics report the ...
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Researcher’s work on silent flagellins earns major award
Sara Clasen, a postdoctoral fellow in the Institute for Biomedical Sciences at Georgia State University, is the grand prize winner of the prestigious 2023 NOSTER & Science Microbiome Prize.
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Molnupiravir dose of human effect size-equivalent blocks Covid transmission in ferrets
Two oral drugs provide equivalent therapeutic benefit in preventing severe COVID-19 in animal models, but only molnupiravir efficiently blocked SARS-CoV-2 transmission when administered at a human effect size-equivalent dose.
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Gut microbiomes of mouse pups change for good when nursing mothers fed low-fibre diet
Researchers have found that when nursing mouse mothers are fed a low-fibre diet, their offspring’s microbiome is permanently altered, leading to gut inflammation and obesity.