All ensitrelvir articles
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NewsScientists assess efficacy of clinical drugs targeting SARS-CoV-2 main protease
A critical player in the virus’s life cycle is the main protease (Mpro), also known as NSP5 or 3CL protease, which plays a crucial role in the cleavage and maturation of SARS-CoV-2 proteins within the host cells.
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NewsStudy finds evidence of resistance to COVID-19 drugs
Resistance to Paxlovid is already evident among viral SARS-CoV-2 variants currently circulating globally, indicating that this stand-alone drug known as a protease inhibitor could soon become less effective in treating COVID-19 infections, a new study suggests.
