All Editorial articles – Page 75
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Newer hepatitis B vaccine shows promise as booster for health care workers
A new study compares the effectiveness of Heplisav-B, a new hepatitis vaccine, vs. standard hepatitis B vaccines as a booster in previously vaccinated individuals.
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Evaluating DNA impurities in recombinant adeno-associated virus
A new study indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as single-stranded DNA.
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Biogenic construction: The new era of civil engineering
Inspired by the concept of harmonious coexistence between humans and nature, a new concept, biogenic construction, for civil engineering is proposed in a new paper.
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New study reveals a safer alternative for long-term hepatitis B treatment
Researchers have studied the effects of switching from long-term tenofovir disoproxil fumarate to the antiviral besifovir dipivoxil maleatein (BSV) in patients with chronic hepatitis B. Switching to BSV may improve patient kidney and bone health.
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Many patients with chlamydia and gonorrhea are not receiving CDC-recommended treatment in primary care
Many patients with chlamydia and gonorrhea in primary care settings do not receive the recommended treatment, a new study reveals. This gap in care may contribute to ongoing STI transmission and adverse health outcomes, particularly among marginalized populations.
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Rapid and accurate diagnosis of urinary tract infections using targeted next-generation sequencing
A study shows that tNGS demonstrates advantages in rapid and accurate UTI diagnosis, particularly in detecting polymicrobial infections and analyzing antibiotic resistance genes. It shows promise as an effective complementary tool for UTI diagnostics.
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Breaking antibiotic-resistant bacteria’s protective shields opens door for immune system response
Researchers have made progress in uncovering how Streptococcus pneumoniae constructs its capsule, which serves as a protective shield. This capsule is a primary target for vaccine development.
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Study evaluates airborne transmission risk of mpox compared to COVID-19 and smallpox
Scientists have found that the inhaled infectious dose of mpox is at least 100 times lower than that of SARS-CoV-2 and smallpox, making efficient respiratory aerosol transmission highly unlikely in its current form - but future viral evolution could alter this dynamic.
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‘Low-sugar’ vaccine can provide broad immunity against coronavirus variants
A universal vaccine for coronaviruses removes sugar molecules from an area of a coronavirus spike protein that rarely mutates and creates effective and plentiful antibodies to inactivate the virus.
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UKHSA highlights pathogens of greatest risk to public health in bid to boost preparedness
The UK Health Security Agency (UKHSA) has today published its view on the pathogen families that could pose the greatest risk to public health, in a bid to focus and guide preparedness efforts against these threats.
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Scientists ID natural products targeting SARS-CoV-2 - including caffeine
Researchers used computational methods to identify potential inhibitors of SARS-CoV-2 spike proteins, revealing promising natural compounds for guiding antiviral drug development, including caffeine.
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New study sheds light on how bacteria ‘vaccinate’ themselves with genetic material from dormant viruses
Scientists have gained understanding on how bacteria defend themselves from phages, through gaining “memories” from predecessor dormant phages. The study will inform new phage therapies for bacterial infections that confer resistance to antibiotics.
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Simulation model shows potential affordability of preventative HIV therapy for infants
A type of cost-effective HIV neutralizing antibodies was evaluated to prevent the viral infection in infants during breastfeeding in high HIV prevalance countries. This treatment option is comparatively cheaper and has high clinical impacts in high HIV burden settings to achieve global elimination.
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Movie reveals DNA unzipping mechanism with implications for viral and cancer treatments
A detailed unwinding mechanism of the double-stranded DNA has been uncovered for the first time using cutting-edge technology, revealing how cells begin the crucial process of copying their genetic material.
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Green recipe: Engineered yeast boosts D-lactic acid production
An optimal combination of genetic “recipe” in a yeast strain achieves high yields of D-lactic acid production from methanol, advancing eco-friendly and sustainable biomanufacturing.
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Influenza of avian origin confirmed in a sheep in Yorkshire
The UK’s Chief Veterinary Officer has confirmed a case of influenza of avian origin (H5N1) in a single sheep in Yorkshire following repeat positive milk testing.
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Bartonella and babesia found in brain tissue of child with seizures
In a new case study, researchers have found Bartonella henselae, Babesia odocoilei and Babesia divergens-like MO-1 DNA in brain tissue samples from a young child with seizures and suspected Rasmussen’s encephalitis.
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Origin of life: How microbes laid the foundation for complex cells
Researchers examining links between Asgard archaea and eukaryotes have shown that Asgard tubulins form similar microtubules, albeit smaller than those in their eukaryotic relatives. Unlike actin, these tubulin proteins appear in very few species of Asgard archaea.
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Antibody-based therapy is several steps closer to treat lethal mucormycosis
A new paper discusses the use of monoclonal antibodies to target a key fungal cell surface protein, CotH, which enables the Mucorales fungus to invade human cells and cause mucormycosis, which has high mortality rates in people with weakened immune systems.
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New model predicts how bacteria navigate obstacles to spread
A scientist has developed the first analytical model for predicting how bacteria spread in environments filled with obstacles. This model will help inform strategies for curbing bacterial infections or for designing better drug delivery.