All Editorial articles – Page 30
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Immune ‘dysregulation’ present prior to infection predicts severe responses
A study shows that a common gene signature of immune health or dysfunction predicts severe outcomes from infection, and is present in people with known risk factors such as being a smoker or having a high body mass index, even before they encounter a pathogen.
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Enzymes from fungi can help extract plant components for biofuels and bioplastics
Plant cell wall components such as cellulose are abundant sources of carbohydrates that are widely used in biofuels and bioproducts. Investigators have found that a combination of fungal enzymes can efficiently degrade plant biomass to allow for extraction.
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War, trade and agriculture spread rice disease across Africa
Since the mid-1800s, human activities have rapidly facilitated the spread of rice yellow mottle virus (RYMV), a pathogen that infects rice, far and wide across Africa, according to a new study.
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Researchers to harness the power of fungi for water filters
A groundbreaking project exploring the power of fungi to combat agricultural pollution is making significant strides, with researchers looking to begin live field trials later this year.
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Nominations for the 2025 Horizon Awards now open
Applied Microbiology International has announced the launch of nominations for the 2025 Horizon Awards, which celebrate the brightest minds in the field and promote the research, group, projects, products and individuals who help shape the future of applied microbiology.
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International comparison reveals gender differences in antimicrobial resistance
A recent study analysed the DNA map of more than 14,000 gut metagenomes in a global dataset and found differences in antibiotic resistance between genders. In high-income countries, women had more antibiotic resistance genes than men.
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Researchers examine the impact of mycoestrogen exposure on birth outcomes
Exposure to mycotoxins – a broad group of harmful substances produced by mold – during pregnancy may impact placental function, which could result in lower birthweight in humans.
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Depression linked to a less diverse oral microbiome
A study found that people with less diversity in their oral microbiomes were more likely to have symptoms of depression. Smoking, drinking, and dental care also influenced the relationship between the oral microbiome and depression.
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Machine learning method helps bring diagnostic testing out of the lab
A new point-of-care biosensing method, dubbed LOCA-PRAM, improves the accessibility of biomarker detection by eliminating the need for technical experts to perform the image analysis.
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Study validates DenovAI’s platform for programmable de novo-designed protein therapeutics
Researchers introduce a new class of experimentally validated AI-driven protein design tools that have the potential to accelerate drug development.
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Paper-based devices diagnose malaria in asymptomatic people
Devices made with cheap strips of paper have outperformed two other testing methods in detecting malaria infection in asymptomatic people in Ghana – a diagnostic advance that could accelerate efforts to eliminate the disease, researchers say.
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Scientists team up to identify infectious diseases using AI and hyperspectral imaging
A collaboration will expand patented technology to detect viral signatures in animals. ESS Protect – Animal will offer rapid, non-invasive, and contactless screening for bovine respiratory disease (BRD) using hyperspectral imaging and advanced machine learning.
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Illuminated changes: Enhancing D-lactic acid output with UV irradiation
Researchers have developed a Komagataella phaffii (K. phaffii) yeast strain that can efficiently produce D-lactic acid, a raw material for pharmaceuticals and bioplastics, from methanol.
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Immune tolerance to gut microbes is initiated by a key bacterial sensor
A study has found that the body’s immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING—normally considered a trigger for inflammation.
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AI could accelerate protein engineering – key for developing new medicines
An AI approach developed by researchers from the University of Sheffield and AstraZeneca could make it easier to design proteins needed for new treatments.
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Scientists decipher HIV-1 transcription initiation and elongation from single-molecule imaging data
Scientists have developed a dual-driven framework based on single-molecule imaging data and stochastic dynamic modeling to infer HIV-1 transcription dynamics.
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Launch of first-in-human clinical trial of next-generation rotavirus vaccine delivered via dissolvable microarray technology
Scientists have announced the first clinical trial of a novel rotavirus vaccine, CC24, delivered via dissolvable microarray technology, is now enrolling participants.
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Excessive use of disinfectants in intensive care patients may increase the risk of antibiotic-resistant infections
An international study has, for the first time, revealed a strong and direct link between the rise of antibiotic-resistant bacteria and universal disinfection procedures applied to patients in intensive care units.
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AFYREN begins new phase of industrial strategy as first plant AFYREN NEOXY achieves continuous production
Greentech company AFYREN offering industrial customers bio-based, low-carbon products through fermentation technology based on a circular model, announced its first plant has achieved continuous production, enabling acceleration of commercialization.
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Gut microbes may help in recognizing and treating pancreatic cancer
A new international cooperation study indicates that in the future pancreatic cancer may be detected at an early stage with the help of gut microbes. Gut microbes may also offer solutions for therapy development.