All Early Career Research articles
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Pregnancy enhances natural immunity to block severe flu
Scientists discover a natural flu defense mechanism that activates in the nasal cavity during pregnancy.
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Satellite evidence bolsters case that climate change caused mass elephant die-off
New analysis showing carcass distribution and algae in watering holes points to climate-induced poisoning of over 300 African elephants.
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Bacteria ditch tags to dodge antibiotics
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to new research. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of antibiotic resistance.
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Photodynamic therapy with annatto colorant found to be effective against bad breath
A study by researchers working in Brazil shows that antimicrobial photodynamic therapy in which blue light targets annatto colorant is a feasible and effective option for treatment of halitosis in mouth-breathing children.
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A new tool to predict the most effective phage cocktail
Researchers have developed a simple and effective new tool that recommends the best possible phage cocktail for a given patient. Paving the way for personalized phage therapies to treat antibiotic-resistant bacterial infections.
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Hot water best for sanitizing in-shell pecans, sanitizers prevent cross-contamination
To identify best practices for microbial safety in the pecan market, scientists conducted a study to evaluate methods of sanitizing pecans against Shiga toxin-producing E. coli, also known as STEC.
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Probiotic may counteract fire-retardant chemical damage
A mouse study reports that probiotic supplementation can reduce the negative impacts of polybrominated diphenyl ethers, or PBDEs - fire-retardant chemicals - on neurodevelopment, behavior, and metabolism.
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Gut feelings: Social connections change our microbiomes
Friends tend to share common interests, tastes, lifestyles, and other traits, but a new Yale-led study demonstrates that similarities among buddies can also include the makeup of the microbes lining their guts. The study, published Nov. 20 in the journal Nature, examined the relationship between the structure ...
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Seemingly ‘broken’ genes in coronaviruses may be essential for viral survival
Some coronaviruses, including Covid-19 have extra ‘accessory’ genes in addition to the usual minimal viral set and researchers have found that some of these viral genes have stuck around even though they don’t produce a working protein.
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Understanding neonatal infectious diseases in low- and middle-income countries
Researchers have conducted an in-depth study on the epidemic status, secular trends, and risk factors of 15 common neonatal infectious diseases across low- and middle-income countries (LMICs) from 1990 to 2019.
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Antibacterial material restores the efficacy of antibiotics against resistant bacteria
Research shows that resistant bacteria can regain susceptibility to antibiotics when the treatment is combined with a material equipped with antibacterial peptides.
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Funding boost to bring engineering biology technologies to market
Part of a £2.8 million UKRI seed corn fund has been awarded to the Environmental Biotechnology Innovation Centre (EBIC) to bridge the gap between research and market-ready products and technologies, with comprehensive support and resources for researchers.
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Rule-breaking tuberculosis bacteria challenge growth norms
The rod-shaped tuberculosis (TB) bacterium is the first single-celled organism ever observed to maintain a consistent growth rate throughout its life cycle, a new study reports, hinting at why the pathogen so readily outmaneuvers our immune system and antibiotics.
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Promise in fighting drug-resistant pathogens innovative study shows
A new study has developed an innovative approach to combat antibiotic-resistant bacteria by tagging them with a chimeric agent that activates the immune system towards them.
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Microbial load can influence disease associations, new model reveals
Scientists have developed a new machine-learning model to predict microbial load — the density of microbes in our guts — and used it to demonstrate how microbial load plays an important role in disease-microbiome associations.
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Multidrug-resistant bacterium posing a global public health threat is detected in Northeast Brazil
A strain of Klebsiella pneumoniae that is resistant to all available antibitoics has been detected in Brazil after previously being detected in the United States.
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Breaking down bacterial barriers using bovine gut enzyme
A team of scientists has devised a way to break down biofilms which limit the entry of drugs and help bacteria become resistant to antibiotics, using an enzyme from the cow’s digestive tract.
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Nasal swab tests predict COVID-19 disease severity
New reserach is providing a more precise prediction of COVID-19 severity that can be found by looking at autoantibodies in the nasal cavity, leading to more personalized treatment plans.
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Microbes in mouth reflect lifestyle choices
A new study in Nepal reveals that oral microbiomes differ among traditional foragers, agriculturalists and industrialists, and with behaviors like smoking and diet.
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Infant gut microbiota development predicts future health
Infants’ gut microbiota development follows one of five predictable trajectories, significantly influenced by infant exposures, according to a new study. These are strong indicators of later health outcomes, including allergies, growth patterns, and infections.