All Disease Treatment & Prevention articles – Page 6
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Impact of COVID-19-related nonpharmaceutical interventions on diarrheal diseases and zoonotic salmonella
The results showed that while the detection rate of most foodborne pathogens declined in China during the pandemic there was an abnormal increase in the detection rate of non-typhoidal Salmonella.
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Antibiotics aren’t effective for most lower tract respiratory infections
Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment for lower-respiratory tract infections.
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Biofilms play key role in reducing sensitivity to ionic silver in wound pathogens.
Bacterial pathogens in wounds that have been treated with ionic silver can adapt and become less sensitive - thanks to biofilm formation.
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Mechanism of action of the hepatitis B and D virus cell entry inhibitor bulevirtide deciphered
An international research team has succeeded in deciphering the molecular structure of bulevirtide in complex with the HBV/HDV receptor NTCP at the molecular level.
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Significant decline of neutralising antibodies to monkeypox virus during the first month after vaccination
New research shows that even in men who receive two doses of mpox vaccine intradermally, their level of antibodies to the virus falls to low or zero within the first few months if they have not received a previous smallpox vaccine.
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Scientists have a new tool in the race to improve the diagnosis and prognosis of sepsis
Scientists identify unique molecular signatures of sepsis and use AI to improve diagnosis and identify patients most likely to develop severe symptoms and suffer poor outcomes.
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A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
Scientists repurposed approved drugs that they originally tested to normalize blood vessels surrounding tumors to improve drug delivery to cancer cells.
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Scientists develop an innovative compound effective against malaria and leishmaniasis
Initially designed for malaria, this drug shows high efficacy against leishmaniasis, representing a unique and promising breakthrough for the treatment of both infections.
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Implantable device delivers HIV antiviral with more potency than oral drugs
A study shows that a nanofluidic implant delivered an HIV drug that achieved more potency than other forms of drug administration (oral) and other HIV drugs.
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New understanding of the gut immune system may hold promise for Crohn’s disease patients
A team of scientists have uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn’s disease. The discovery may help define how to treat patients with severe Crohn’s disease.
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Study reveals how virus hijacks insect sperm to control disease vectors and pests
A new study reveals how viral proteins from symbiotic bacteria cause sterility in insects.
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Nanoparticles containing lupeol treat visceral leishmaniasis with scant side effects
In animal tests conducted at São Paulo State University (UNESP), the strategy reduced spleen and liver parasite numbers by 99.9%.
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Scientists reveal what makes ‘bad’ bacteria life-threatening
Researchers have discovered that a mutation allows some E. coli bacteria to cause severe disease in people while other bacteria are harmless, a finding that could help to combat antibiotic resistance.
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Valley fever expert shares ‘state-of-the-art’ knowledge about fungal disease
A new review paper focuses on how fungal diseases present in people with healthy immune systems and examines current diagnostics and treatments.
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Modified phage DNA can kill deadly pathogens
DNA modified from a bacteriophage and put inside Pseudomonas aeruginosa was found to bypass the pathogen’s defense mechanisms to assemble into virions, which sliced through the bacterium’s cell to kill it.
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Green alternative for treating Streptococcus iniae bacteria in hybrid striped bass
Scientists at the United States Department of Agriculture (USDA)’s Agricultural Research Service (ARS) have developed a green antibiotic alternative to treat the deadly pathogen Streptococcus iniae in hybrid striped bass, the fourth most farmed finfish in the United States, according to a recent study. Source: Matt McEntire, ...
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Researchers create safer form of Coxiella burnetii for scientific use
Scientists have unexpectedly discovered that the weakened form of the bacteria Coxiella burnetii (C. burnetii) not typically known to cause disease, has naturally acquired an ability to do so.
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Study uncovers how gum disease aggravates COPD
A new study shows how periodontitis, an oral disease, activates immune cells associated with aggravated progression of COPD.
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Consortium to tackle the effect of climate change on diarrheal diseases
Thanks to a Horizon Europe grant, Amsterdam UMC together with the Amsterdam Institute for Global Health and Development, is set to lead a global consortium to improve policies and interventions
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Intravaginal sponge can make candidiasis treatment more comfortable and effective
A biodegradable sponge made of chitosan, a biopolymer derived from the shells of crustaceans, releases medication slowly into the organism and makes treatment of candidiasis more comfortable and effective.