All Disease Treatment & Prevention articles – Page 3
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New phage platform pinpoints viruses that can deliver a knockout blow for killer bacteria
An international group of microbial experts has launched a powerful and flexible free online genomic toolkit for more rapid development of phage therapy. They say it is capable of assessing if a phage is suitable for a targeted therapy in under 10 minutes.
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NIH-funded clinical trial will evaluate new dengue therapeutic
A clinical trial is testing an experimental treatment designed to help people suffering the effects of dengue. An investigational therapeutic will be administered to adult volunteers who have been exposed to a weakened strain that causes a mild form of the disease.
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Antibody treatment prevents severe bird flu in monkeys
A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, a new study reports.
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Study finds three new safe, effective ways to treat drug-resistant tuberculosis
An international clinical trial has found three new safe and effective drug regimens for tuberculosis that is resistant to rifampin, the most effective of the first-line antibiotics used to treat TB.
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Could faecal microbiota transplantation help patients heal after stem cell transplantation?
A study, from a part of an ongoing clinical trial, has reported the safety of oral faecal microbiota transplantation (FMT) to help patients recover from the loss of gut microbiome after allogeneic stem cell transplantation for blood cancers.
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New study highlights role of lean red meat in gut and heart health as part of a balanced healthy diet
A research has suggested that a balanced and healthy dietary pattern that includes lean red meat has a beneficial role in gut microbiota changes and cardiovascular health.
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Structural insights reveal potential drug target in trypanosome parasites
A research group has recently characterised the structural differences between human and trypanosomal nuclear cap-binding complex, a key player in cellular RNA metabolism, for future drug development of trypanosomal diseases.
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Shorter, smarter, safer: Short-course antibiotics can revolutionize healthcare
Researchers suggest that short-course antibiotic treatment could be the next game-changing strategy to treat ventilator-associated pneumonia (VAP) in various economic settings. It provides a cost-effective and practical approach that benefits both patients and the healthcare systems.
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New paper creates roadmap for the next generation of bioelectronic medicine
A new paper offers a roadmap to the future of bioelectronic medicine — which makes use of electrical signals instead of drugs to diagnose and treat disease.
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Dihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
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Scientists uncover structure of critical component in deadly Nipah virus
Through the structural and functional study of the deadly Nipah virus, a research team has identified a crucial viral component, viral polymerase complex, within its multiplication machinery, with which a part of the enzyme could potentially serve as a therapeutic target.
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Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials
A promising research study in treating high mortality late-stage cancers with a non-toxic bacterial therapy - BacID - has proven to be safe and more targeted. The newly developed treatment would undergo clinical trials with cancer patients in 2027.
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Effectiveness and safety of tenofovir amibufenamide in the treatment of chronic hepatitis B: A real-world, multicenter study
A new study aimed to evaluate the real-world effectiveness and safety of tenofovir amibufenamide (TMF) in a cohort of patients with chronic hepatitis B (CHB).
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Antibiotic treatment for drug-resistant tuberculosis found to be safe and effective in clinical trial
Two clinical trials were conducted to successfully test an oral antibiotic levofloxacin for the preventive treatment of multidrug-resistant tuberculosis (MDR-TB).
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Promising COVID-19 vaccine development in animal trials
Researchers developed a COVID-19 vaccine that deploys virus-like particles (VLPs) for immunity stimulation in mice.
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Virus that threatened humanity opens the future
Researchers have developed an innovative therapeutic platform by mimicking the intricate structures of viruses using artificial intelligence.
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New guidelines unveil advanced strategies for HIV treatment and prevention
The International Antiviral (formerly AIDS) Society-USA (IAS-USA) has published new international guidelines for the treatment and prevention of HIV, based on significant advances in antiretroviral therapies and new prevention strategies such as pre-exposure prophylaxis.
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Biomarker test could significantly reduce antibiotic use in sepsis
A major UK patient trial of a new biomarker testing protocol for sepsis, has shown it is possible to safely stop antibiotic treatment earlier than current care.
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Microbial load can influence disease associations, new model reveals
Scientists have developed a new machine-learning model to predict microbial load — the density of microbes in our guts — and used it to demonstrate how microbial load plays an important role in disease-microbiome associations.
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Research shows new method to safely remove dangerous heart infections without surgery
Doctors used a new catheter-based approach to draw out resistant pockets of infection that settle in the heart, known as right-sided infective endocarditis, without surgery.