All Disease Treatment & Prevention articles – Page 2
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NewsStudy: Smartwatches could end the next pandemic
Everyday smartwatches are extremely accurate in detecting viral infection long before symptoms appear — new research shows how they could help stop a pandemic before it even begins.
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NewsNew test identifies prior infection by zika virus and all four dengue virus serotypes
An alternative approach is developed to detect and distinguish between antibodies induced by the dengue and zika virus in blood samples. The strategy can be used to orient public health policy and evaluate the efficacy of dengue vaccines.
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NewsWorld first clinical trial will study specialized ‘poop pills’ to improve treatment of advanced pancreatic cancer
A world-pioneering fecal microbiota transplantation pill will undergo a clinical trial, aiming to improve immune responses by remodifying the gut microbiome in patients with advance pancreatic cancer.
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NewsGastric bacteria ‘leaking across stomach lining’ could indicate risk of gastric cancer
A new discovery in the roles of gastric microbiota bacteria and Helicobacter pylori across the stomach lining during pre-cancerous stage of gastric cancer development could be the missing link for engineering future therapeutic intervention.
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NewsA*STAR spin-off NalaGenetics implements nationwide drug reaction screening for leprosy patients in Indonesia
NalaGenetics, a spin-off from A*STAR Genome Institute of Singapore (A*STAR GIS), will be transforming leprosy treatments in Indonesia with a nationwide genetic screening programme with their PGx1301 diagnostic kit.
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NewsDesigning self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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NewsHerpesviruses may contribute to Alzheimer’s disease via transposable elements
Researchers have outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer’s disease in aging brains, and also share two FDA-approved, commercially available drugs that reverse this pathway in a laboratory setting.
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NewsScientists invent new drug candidates to treat antibiotic-resistant bacteria
Researchers designed a new family of antibiotics that’s a variation of an existing drug called vancomycin, which is used as a last resort for extremely ill patients. The new version of vancomycin targets, bonds to and renders inactive two different parts of a molecule on the surfaces of pathogenic bacteria.
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NewsNew therapy may effectively control HIV in Uganda
Clinical trials showed an effective antiviral drug, known as lenacapavir, against HIV in Uganda, and has also been tested for drug resistance in different subtype strains.
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NewsNeonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
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NewsNovel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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NewsFungal compound could help protect against influenza
A preclinical trial uncovers how beta-glucan, a compound found in all fungal cell wall, can ‘reprogram’ immune cells to prevent lung inflammation from influenza and lower the risk of death by the host immune responses.
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NewsScientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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NewsResearchers unlock new potential porcine virus treatment
Researchers have identified a novel small molecule for the development of preventative treatment for porcine reproductive and respiratory syndrome virus (PRRSV).
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NewsMpox: a better understanding of tecovirimat resistance
Through biochemical and structural studies, researchers managed to find out how the mutation of an enzyme could affect the interactions between it and the antiviral drug against mpox virus, tecovirimat, hence leading to a better understanding in developing new therapeutic approach against all mpox strains.
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NewsMicrobiome as a potential key to better treatment: Clinical study on new therapy for Crohn’s disease
A joint research project has found that a combination of dietary therapy and fecal microbiome transfer (FMT) greatly alleviate intestinal inflammation in mice. A clinical trial on this new therapeutic approach is under way to potentially treat Crohn’s disease.
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NewsA realistic ‘micro-gut’ model reflects the relationship between gut microbes and human diseases
An innovative and more physiologically relevant 3D micro-gut model, known as Gut-Microbiome on a chip (GMoC), provides an in-depth understanding of the complex interactions between the microbial community within the gut microbiome and their impacts on human gut health.
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NewsWhy some kids get sicker: The hidden power of nose bacteria
A scoping review unravels how bacterial colonization in the respiratory tract impacts both the severity of respiratory syncytial virus (RSV) infections and long-term respiratory health in children.
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NewsAI accelerates the search for new tuberculosis drug targets
A novel biotechnology was developed to utilize artificial intelligence (AI) as a high-throughput way to identify more effective antimicrobial candidates to treat the multi-drug resistant Mycobacterium tuberculosis and understand their underlying modes of action.
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NewsFirst success in overcoming gene therapy challenges deploys nanomachines loaded with wine ingredients
Scientists have demonstrated the ability to overcome significant challenges in gene therapy using adeno-associated virus vectors (AAV) by employing a novel smart nanomachine equipped with AAV.