All Disease Treatment & Prevention articles
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Oral microbes linked to increased risk of pancreatic cancer
Twenty-seven species of bacteria and fungi among the hundreds that live in people’s mouths have been collectively tied to a 3.5 times greater risk of developing pancreatic cancer, a study shows.
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Plant-derived compound has antimicrobial and anti-inflammatory effects against periodontal disease
Morin-based powder, extracted from guava leaves, apple peel, and figs, can be slowly released with the help of polymers and serve as an alternative to antibiotics.
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Blood microbial DNA distinguishes liver cancer from metastatic lesions
A simple blood test analyzing microbial DNA could help doctors tell apart primary liver cancer from colorectal cancer that has spread to the liver, according to a new study.
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Targeted delivery of microRNA sponge short-hairpin RNA via VIR-inspired biotechnical vector
The Vir-inspired Biotechnical Vector (VIBV) is a novel hybrid platform that combines viral and non-viral elements with nanotechnology to enable personalized, tumor-specific gene therapy.
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Microbiotica announces completion of recruitment in its international phase 1b trial of microbiome co-therapy
Microbiotica, a clinical-stage biopharma company developing a pipeline of oral precision microbiome medicines called live biotherapeutic products (LBPs), announces that patient recruitment is complete in its advanced melanoma (MELODY-1) trial.
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Bout of cystitis may signal presence of urogenital cancers in middle-aged adults
A bout of the common bladder infection, cystitis, may signal the presence of urogenital cancers—which affect parts of the body involved in reproduction and excretion—in middle aged adults, suggests research. The risks seem to be especially high within 3 months of infection.
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Type 2 diabetes may double risk of sepsis, large community-based study suggests
Living with type 2 diabetes (T2D) may double the risk of developing sepsis—with those aged younger than 60 years and men particularly susceptible, according to a long-term community-based study in Australia.
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Microbial allies: Bacteria help fight against cancer
An international team of scientists have discovered that microbes associated with tumours produce a molecule that can control cancer progression and boost the effectiveness of chemotherapy.
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Your genes could prune your gut bugs and protect you from disease
Researchers uncover genetic peptides that shape gut bacteria and protect against obesity and diabetes, revealing gut health is influenced by more than just diet and opening doors to personalised treatments.
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MD Anderson and Nature to co-host conference on the tumor ecosystem
The University of Texas MD Anderson Cancer Center and Springer Nature will co-host a free, in-person conference to explore the latest research on the tumor ecosystem, highlighting how its components influence cancer development, progression, diagnosis and treatment.
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Scientists report the first use of CRISPR activation to treat a cardiac disease in mice
Researchers have demonstrated for the first time that CRISPR-based gene activation (CRISPRa) can be used to treat genetic heart disease in vivo. The study paves the way for novel targeted therapies for patients with genetic cardiac disorders.
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Can a healthy gut microbiome help prevent childhood stunting?
Researchers find gut microbiome turnover in children is linked to poor growth outcomes, pointing to microbiome-based diagnostics for malnutrition.
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Frailty fuels gut imbalance and post-surgery gastrointestinal risks
Scientists found that residual intra-abdominal microbes, especially in frail patients, drive gastrointestinal complications after bladder cancer surgery.
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Scientists unveil viral mechanism behind nasopharyngeal cancer spread
Researchers have discovered that the Epstein-Barr virus (EBV), a common human virus closely linked to nasopharyngeal carcinoma (NPC), can change the 3D structure of the human genome inside cancer cells, much like assembling building blocks.
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Routine Helicobacter pylori screening does not significantly reduce upper gastrointestinal bleeding in patients after a heart attack
Routine Helicobacter pylori screening did not significantly reduce the risk of upper gastrointestinal bleeding in patients hospitalised for myocardial infarction (MI), according to new research.
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Connection among gut fungi, genetics and disease risk in humans identified
A novel genome-wide association study sheds light on the human genetic determinants of the fungal component of the human microbiome and their relation to chronic disease.
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Clinical study shows that nasal spray containing azelastine reduces risk of coronavirus infection by two-thirds
In addition to showing a marked reduction in coronavirus infections, the azelastine group also displayed fewer symptomatic SARS-CoV-2 infections, a lower overall number of confirmed respiratory infections, and, unexpectedly, a reduced incidence of rhinovirus infections, another major cause of respiratory illness.
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Unlocking how bacteria bounce back after antibiotics
A groundbreaking study has uncovered how Escherichia coli (E. coli) persister bacteria survive antibiotics by protecting their genetic instructions. The work offers new hope for tackling chronic, recurring infections.
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Therapeutic vaccination against HPV-related tumors: Nanoparticles make the difference
Researchers have developed a therapeutic vaccination concept that can mobilize the immune system to target cancer cells. Virus peptides coupled to silica nanoparticles can elicit effective T-cell responses against HPV-related tumors. In a mouse model, the nanoparticle-based vaccine was able to partially or completely suppress HPV-related tumors.
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Researchers uncover relationship between gut fungi, human genetic variation and disease risk
A study uncovers evidence of the first ternary relationships between human genetic variation, variation in gut mycobiome, and risk of developing chronic disease.