All Disease Treatment & Prevention articles
-
NewsNew therapy may effectively control HIV in Uganda
Clinical trials showed an effective antiviral drug, known as lenacapavir, against HIV in Uganda, and has also been tested for drug resistance in different subtype strains.
-
NewsNeonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
-
NewsNovel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
-
NewsFungal compound could help protect against influenza
A preclinical trial uncovers how beta-glucan, a compound found in all fungal cell wall, can ‘reprogram’ immune cells to prevent lung inflammation from influenza and lower the risk of death by the host immune responses.
-
NewsScientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
-
NewsResearchers unlock new potential porcine virus treatment
Researchers have identified a novel small molecule for the development of preventative treatment for porcine reproductive and respiratory syndrome virus (PRRSV).
-
NewsMpox: a better understanding of tecovirimat resistance
Through biochemical and structural studies, researchers managed to find out how the mutation of an enzyme could affect the interactions between it and the antiviral drug against mpox virus, tecovirimat, hence leading to a better understanding in developing new therapeutic approach against all mpox strains.
-
NewsMicrobiome as a potential key to better treatment: Clinical study on new therapy for Crohn’s disease
A joint research project has found that a combination of dietary therapy and fecal microbiome transfer (FMT) greatly alleviate intestinal inflammation in mice. A clinical trial on this new therapeutic approach is under way to potentially treat Crohn’s disease.
-
NewsA realistic ‘micro-gut’ model reflects the relationship between gut microbes and human diseases
An innovative and more physiologically relevant 3D micro-gut model, known as Gut-Microbiome on a chip (GMoC), provides an in-depth understanding of the complex interactions between the microbial community within the gut microbiome and their impacts on human gut health.
-
NewsWhy some kids get sicker: The hidden power of nose bacteria
A scoping review unravels how bacterial colonization in the respiratory tract impacts both the severity of respiratory syncytial virus (RSV) infections and long-term respiratory health in children.
-
NewsAI accelerates the search for new tuberculosis drug targets
A novel biotechnology was developed to utilize artificial intelligence (AI) as a high-throughput way to identify more effective antimicrobial candidates to treat the multi-drug resistant Mycobacterium tuberculosis and understand their underlying modes of action.
-
NewsFirst success in overcoming gene therapy challenges deploys nanomachines loaded with wine ingredients
Scientists have demonstrated the ability to overcome significant challenges in gene therapy using adeno-associated virus vectors (AAV) by employing a novel smart nanomachine equipped with AAV.
-
NewsNew phage platform pinpoints viruses that can deliver a knockout blow for killer bacteria
An international group of microbial experts has launched a powerful and flexible free online genomic toolkit for more rapid development of phage therapy. They say it is capable of assessing if a phage is suitable for a targeted therapy in under 10 minutes.
-
NewsNIH-funded clinical trial will evaluate new dengue therapeutic
A clinical trial is testing an experimental treatment designed to help people suffering the effects of dengue. An investigational therapeutic will be administered to adult volunteers who have been exposed to a weakened strain that causes a mild form of the disease.
-
NewsAntibody treatment prevents severe bird flu in monkeys
A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, a new study reports.
-
NewsStudy finds three new safe, effective ways to treat drug-resistant tuberculosis
An international clinical trial has found three new safe and effective drug regimens for tuberculosis that is resistant to rifampin, the most effective of the first-line antibiotics used to treat TB.
-
NewsCould faecal microbiota transplantation help patients heal after stem cell transplantation?
A study, from a part of an ongoing clinical trial, has reported the safety of oral faecal microbiota transplantation (FMT) to help patients recover from the loss of gut microbiome after allogeneic stem cell transplantation for blood cancers.
-
NewsNew study highlights role of lean red meat in gut and heart health as part of a balanced healthy diet
A research has suggested that a balanced and healthy dietary pattern that includes lean red meat has a beneficial role in gut microbiota changes and cardiovascular health.
-
NewsStructural insights reveal potential drug target in trypanosome parasites
A research group has recently characterised the structural differences between human and trypanosomal nuclear cap-binding complex, a key player in cellular RNA metabolism, for future drug development of trypanosomal diseases.
-
NewsShorter, smarter, safer: Short-course antibiotics can revolutionize healthcare
Researchers suggest that short-course antibiotic treatment could be the next game-changing strategy to treat ventilator-associated pneumonia (VAP) in various economic settings. It provides a cost-effective and practical approach that benefits both patients and the healthcare systems.
