All Disease Treatment & Prevention articles
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NewsSimulation model shows potential affordability of preventative HIV therapy for infants
A type of cost-effective HIV neutralizing antibodies was evaluated to prevent the viral infection in infants during breastfeeding in high HIV prevalance countries. This treatment option is comparatively cheaper and has high clinical impacts in high HIV burden settings to achieve global elimination.
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NewsUpdated guidelines for pediatric Mycoplasma pneumoniae infection
In light of the rise in antibiotic resistance, new guidelines are released with detailed recommendations of diagnosis and treatment strategies for pediatric Mycoplasma pneumoniae pneumonia (MPP), along with the means to manage severe complications.
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NewsResearchers discover Achilles heel of Lyme disease pathogen
Researchers discovered and investigated an unique enzyme used in the pathway specific to Borrelia burgdorferi, the parasite that causes Lyme disease. The enzyme serves as the ideal genus-specific target for therapeutic intervention.
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NewsFDA-approved dialysis drug may help fight against antimicrobial resistance
In account of the imminent threat of antimicrobial resistance (AMR), a study revealed that the FDA-approved sevelamer, which is used to treat chronic kidney disease undergoing dialysis, is successful in the removal of other off-target antibiotics (vancomycin and daptomycin) from the gut.
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NewsResearch uncovers new strategy to reduce tissue damage from flesh-eating bacteria
A new study reveals a novel approach to mitigating tissue damage caused by Streptococcus pyogenes, the flesh-eating bacterium responsible for severe infections such as necrotizing fasciitis.
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NewsCurrent antivirals likely less effective against severe infection caused by bird flu virus in cows’ milk
Scientists found that in a preclinical model, two FDA–approved flu antivirals generally did not successfully treat severe H5N1 infections. Meanwhile, the route of infection, whether through the eye, the nose or the mouth, significantly impacts effectiveness.
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NewsNIH-sponsored trial of Lassa vaccine opens
A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.
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NewsNew CRISPR-based diagnostic test detects multidrug-resistant pathogens in blood without amplification
A highly sensitive amplification-free CRISPR-based diagnostic test is developed to rapidly detect pathogens, including multidrug-resistant bacteria, at low concentrations in blood samples.
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NewsOlder adults might be more resistant to bird flu infections than children
Previous exposures to seasonal flu strains could prime the immune system to produce antibodies against the current version of H5N1 avian influenza virus in older adults, whilst children would benefit more from H5N1 vaccinations.
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NewsFirst coronavirus similar to MERS is found in bats in South America
A novel coronavirus, which shares high genetic similarities with MERS-CoV, was identified in bats in the state of Ceará, Brazil. Experiments to find out whether it can infect humans are set to take place in collaboration with Hong Kong University.
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NewsCOVID-19 discovery opens door to new treatments for chronic lung problems
A discovery was made to understand how severe viral infections, like COVID-19 and flu could destroy the ability of immune cells to repair the tissue damage in lungs, causing long COVID and other chronic lung diseases.
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NewsTecovirimat is safe but ineffective as treatment for clade II mpox
The antiviral drug tecovrimat used without other antivirals did not reduce the time to clinical resolution of clade II mpox lesions or improve pain control among adults in an international clinical trial.
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NewsDrug may prevent COVID-19 in exposed people within households, major trial finds
An international clinical trial of the oral antiviral drug, ensitrelvir, which has been proved to prevent COVID-19 cases, was conducted and found to be very effective. The drug will be awaiting for approval before becoming widely available.
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NewsNew immune mechanism revealed in the cellular trash
The enzyme, proteasomes known for its protein degradation and recycling system, has found to serve another useful purpose that provides promising alternatives for strengthening immune defenses against deadly diseases.
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NewsPrevalence of neutralizing antibodies to AAV2 and AAV9 in individuals with Niemann-Pick disease
A new study shows that more than half of individuals with Niemann-Pick disease, type C1 (NPC1) who were tested lacked neutralizing antibodies against either adeno-associated virus (AAV) 2 or AAV9.
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NewsNew discovery and grant to accelerate Strep A vaccine efforts
With a large sum of research funding and multinational contributions, the world’s only Strep A human challenge model will be used to resolve logistical issues and speed up the development of a successful Strep A vaccine.
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NewsEarly-life gut microbes may protect against diabetes, research in mice suggests
A research discovered that the colonization of a fungus called <i>Candida dubliniensis</i> in the early life gut microbiome of mice, is able to promote growth of pancreatic beta cells in the presence of macrophages to restore blood insulin level and improve metabolic functions, thus reducing risks of type 1 diabetes.
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NewsA 'Trojan Horse' approach to develop new antimalarial drugs
Researchers have discovered a key process whereby malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment.
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NewsNew antibodies show potential to defeat all SARS-CoV-2 variants
Researchers discovered that a paired combination of antibodies binding to the two domains of the SARS-CoV-2 viral particle showed promising results in elimination of all virus variants caused in the COVID-19 pandemic.
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NewsStudy: Smartwatches could end the next pandemic
Everyday smartwatches are extremely accurate in detecting viral infection long before symptoms appear — new research shows how they could help stop a pandemic before it even begins.