All Crohn’s disease articles
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News
Possible trigger of Crohn’s disease discovered: Dysfunctional mitochondria disrupt gut microbiome
Disruptions of mitochondrial functions have an influence on Crohn’s disease, a connection now revealed by researchers who showed that defective mitochondria in mice trigger symptoms of chronic intestinal inflammation and influence the microbiome.
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$5.6 million grant awarded to target treatments for IBS, Crohn’s and Ulcerative colitis
An “out-of-the-box” study has been awarded a $5.6 million NIH grant to target treatments for IBS, Crohn’s, Ulcerative Colitis and more.
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Study reveals possible triggers for inflammatory bowel disease
A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD develops.
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New understanding of the gut immune system may hold promise for Crohn’s disease patients
A team of scientists have uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn’s disease. The discovery may help define how to treat patients with severe Crohn’s disease.
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Deep dive into the gut unlocks new disease treatments
Researchers say it’s not only possible to map just what species are in the gut microbiome but how they interact and how that can affect the whole body.
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Oral lipid nanoparticle drug can prevent development of colitis-associated cancer
An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by researchers in the Institute for Biomedical Sciences at Georgia State University. The findings published in the journal Pharmaceutics report the ...
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Microgel treatment helps ‘good’ gut bacteria and clears out the ‘bad’
Researchers have developed a microgel delivery system for probiotics that keeps ‘good’ bacteria safe while actively clearing out ‘bad’ ones.
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Sleep supplement impairs action of gut microbiota
Despite its antioxidant effects and role in regulating sleep cycles, tests show melatonin can worsen inflammation of the intestine and impair the action of gut microbiota.
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Stool transplants more effective than antibiotics for treating recurring, life-threatening gut infections
A new Cochrane Review has found that, compared with standard antibiotic treatment, stool transplantation can increase the number of people recovering from Clostridioides difficile infection from 40% to 77%.
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News
Probiotic ‘backpacks’ could treat inflammatory bowel diseases
Researchers have devised specialised nano-particles that can neutralise molecules linked to inflammatory bowel disease (IBD), and can be attached to beneficial probiotic bacteria targeting the gut.