All Computational Biology articles
-
NewsStudy evaluates airborne transmission risk of mpox compared to COVID-19 and smallpox
Scientists have found that the inhaled infectious dose of mpox is at least 100 times lower than that of SARS-CoV-2 and smallpox, making efficient respiratory aerosol transmission highly unlikely in its current form - but future viral evolution could alter this dynamic.
-
NewsScientists ID natural products targeting SARS-CoV-2 - including caffeine
Researchers used computational methods to identify potential inhibitors of SARS-CoV-2 spike proteins, revealing promising natural compounds for guiding antiviral drug development, including caffeine.
-
NewsSimulation model shows potential affordability of preventative HIV therapy for infants
A type of cost-effective HIV neutralizing antibodies was evaluated to prevent the viral infection in infants during breastfeeding in high HIV prevalance countries. This treatment option is comparatively cheaper and has high clinical impacts in high HIV burden settings to achieve global elimination.
-
NewsMovie reveals DNA unzipping mechanism with implications for viral and cancer treatments
A detailed unwinding mechanism of the double-stranded DNA has been uncovered for the first time using cutting-edge technology, revealing how cells begin the crucial process of copying their genetic material.
-
NewsNew model predicts how bacteria navigate obstacles to spread
A scientist has developed the first analytical model for predicting how bacteria spread in environments filled with obstacles. This model will help inform strategies for curbing bacterial infections or for designing better drug delivery.
-
NewsA study identifies ‘surprising’ cause of sargassum blooms in the Caribbean
A group of interantional researchers identified the cause of sargassum blooms in the tropical Atlantic Ocean using computer modelling. They have modelled the ocean currents, wind pattern and the growth conditions that help them thrive in the region.
-
NewsNew automated method increases the efficiency of bioactive natural product discovery
In light of the technological advancement in machine learning and bioinformatics tools, researchers developed a fully-automated and integrated platform that enables them to easily identify bioactive natural products in Streptomyces.
-
NewsResearchers develop innovative tool for rapid pathogen detection
A powerful pipeline was developed for more efficient and accurate primer design in qPCR that accelerates the diagnostic tests for infectious diseases and facilitates researches in rapidly evolving pathogens.
-
NewsNew insights into phage–bacteria interactions in the gut microbiome
Researchers studied the interactions between bacteria and phages within the gut microbiome and highlighted the significance of the phage community to shape the microbiome that contributes to host health and diseases.
-
NewsMpox: a better understanding of tecovirimat resistance
Through biochemical and structural studies, researchers managed to find out how the mutation of an enzyme could affect the interactions between it and the antiviral drug against mpox virus, tecovirimat, hence leading to a better understanding in developing new therapeutic approach against all mpox strains.
-
NewsWe know what you ate: Detailed protein maps assess intestinal health
A new method has been designed to map the near-exact molecular details of the human and bacterial protein regulations within the host-gut microbiome interactions. These proteins could be used for medical and dietary intervention to maintain intestinal health.
-
NewsNew computer models open door to far more targeted antibiotics
A powerful computer-modelling approach has been developed to give the antibiotics a laser-like precision for targeting specific types of bacteria among specific parts of the human body.
-
NewsMapping evolution of E. coli virulence factor offers refined drug target
Researchers have presented evidence that targeting the K1 capsule can be used as the basis of treatment, paving the way to prevent serious E. coli infections.
-
NewsComputer model of influenza virus shows universal vaccine promise
Researchers have created an atomic-level computer model of the H1N1 virus that reveals new vulnerabilities, suggesting possible strategies for the design of future vaccines and antivirals against influenza.
-
NewsScientists create computer simulation based on digital microbes
Researchers at University of Galway associated with APC Microbiome Ireland, a world-leading SFI Research Centre, have created a resource of over 7,000 digital microbes – enabling computer simulations of how drug treatments work and how patients may respond. The resource is a milestone in scientific understanding of human response to ...
-
NewsResearcher creates world first computational reconstruction of virus in entirety
An Aston University researcher has created the first ever computer reconstruction of a virus, including its complete native genome.