All Clostridioides difficile articles
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NewsStudy expands understanding of how fecal microbiota transplants may work to restore gut health
In a novel study that identified male chromosome genetic material in the intestines of female patients undergoing fecal transplants, researchers say they have significantly expanded scientific understanding of how some of these transplants may succeed and work.
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NewsResearchers hope to develop novel drugs for gastrointestinal disorders by fermenting feces
In a new study, researchers have been cultivating ‘good viruses’ from feces. The goal is to replace fecal capsules now being used in so-called fecal transplants and improve this life-saving treatment through standardization.
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NewsmRNA vaccine created to prevent and treat C. difficile
The vaccine is the first mRNA vaccine against C. difficile and would be the first vaccine in general to successfully ward off the bacterial infection.
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NewsLachnospiraceae could be key to successful fecal transplants
Fecal microbiota transplants are a magic bullet for patients with recurring infections from Clostridioides difficile (C. diff), but researchers are only beginning to understand why.
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NewsHospitals that are understaffed for infection prevention and control have higher rates of infection, study says
Inadequate infection prevention and control staffing levels are associated with higher rates of healthcare-associated infections, according to a new study published today in the American Journal of Infection Control. The study, conducted by the APIC Center for Research, Practice & Innovation, summarizes a pilot project to evaluate ...
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News Scientists discover superbug’s rapid path to antibiotic resistance
Researchers have discovered how a hospital superbug Clostridioides difficile (C.diff) can rapidly evolve resistance to vancomycin. In less than two months the bacteria could develop resistance to 32 times the initial antibiotic concentration.
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NewsStudy identifies protein that affects health of gut microbiota and response to bacterial infection
A new study shows how the presence of a specific protein called IL-22BP affects the composition of the gut microbiota and the body’s response to bacterial infection.
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CareersA conversation at the forefront of human microbiome research
Yang Yue and Professor Alan Walker discuss everything from precision medicine and the omics approach, to challenges in the road ahead and the future of microbiome research.
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NewsDiagnostic stewardship approach to C. diff reduces unnecessary testing
Revised rules for when Clostridioides difficile tests could be ordered helped to reduce inappropriate testing by 20%, which in turn can help rein in the overtreatment of patients.
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NewsNew antibiotic kills pathogenic bacteria, but spares healthy gut microbes
Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.
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NewsViolin resin effective against deadly pathogens - even in dirty conditions
A form of resin used to treat violin strings could double as an effective disinfectant against some of the world’s most deadly diseases, a new study shows.
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NewsNew weapon against the super tough C diff bacteria shows promise
A researcher has demonstrated that a newer generation tetracycline antibiotic, Omadacycline, may be a promising tool in combating the resilient bacteria Clostridioides difficile (C diff), which causes an infection often picked up in hospitals.
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NewsChlorine disinfectant is no more effective than water at killing off hospital superbug
Research explores the impact of using recommended chlorine chemicals to tackle Clostridioides difficile, the most common cause of antibiotic associated sickness in healthcare settings globally.
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NewsNovel C. diff structures are required for infection and offer new therapeutic targets
Iron storage ‘spheres’ inside the bacterium C. diff — the leading cause of hospital-acquired infections — could offer new targets for antibacterial drugs to combat the pathogen.
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NewsResearcher awarded $1.9m to develop model to test phages in the gut
Bryan Hsu, an assistant professor of biological sciences at Virginia Tech, has received a five-year $1.9 million award to develop a model to test the role of lytic bacteriophages, or phages as they are commonly called, in the mammalian gut.
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CareersThe lure of microbes: Getting to know some of the new junior editors at Letters in Applied Microbiology
Applied Microbiology International has just appointed 14 junior editors to its flagship journal Letters in Applied Microbiology (LAM) - so we got to know some of the new crew.
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NewsAcademic-private partnership aims to reduce toxic effects of deadly C. diff
The Center for One Health Research and Nectagen Inc. have received a nearly $275,000 grant to study whether synthetic proteins developed by Nectagen can reduce the toxicity of the digestive bacterium.
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News‘Hospital pathogen’ widespread in Vietnam’s environment
A pathogen considered to be a cause of hospital infection is widespread in Vietnam, turning up in farm soil and pig faeces as well as hospital beds and toilet floor surfaces, with 70% of isolates found to be resistant to at least one class of antimicrobials.
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NewsInter-species interactions may stymie antibiotics
A new study suggests that between-species interactions within the gut microbiome may impact the efficacy of antibiotics aimed at treating C. difficile infections.
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NewsSensor controls how dormant bacteria reawaken
Researchers have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.
